Browsing by Author "Haberer, Jessica E."
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Alzheimer’s Disease and Related Dementias: A Qualitative Assessment of Perceived Training Needs of Primary Healthcare Providers in Rural Southwestern Uganda
Atuhaire, Clara Decent; Obua, Celestino; Rukundo, Godfrey Zari; Haberer, Jessica E.; Wakida, Edith K. (Research square, 2019-09-20)Background: Alzheimer’s disease and related dementias (ADRD)are the third leading cause of years lived with disability, yet patients presenting with ADRD rarely receive proper care at primary healthcare centres (PHC). PHC ... -
Antiretroviral Therapy Adherence Interruptions are Associated with Systemic Inflammation among Ugandans who Achieved Viral Suppression
Musinguzi, Nicholas; Jose, Castillo-Mancilla; Morrow, Mary; Byakwaga, Helen; Mawhinney, Samantha; Burdo, Tricia H.; Boum, Yap; Muzoora, Conrad; Bwana, Bosco M.; Siedner, Mark J.; Martin, Jeffrey N.; Hunt, Peter W.; Bangsberg, David R.; Haberer, Jessica E. (Journal of acquired immune deficiency syndromes, 2019)Background: Residual systemic inflammation, which is associated with non-AIDS clinical outcomes, may persist despite viral suppression. We assessed the effect of antiretroviral (ART) adherence interruptions on systemic ... -
Assessment of HIV antiretroviral therapy adherence by measuring drug concentrations in hair among children in rural Uganda
Olds, Peter K.; Kiwanuka, Julius P.; Nansera, Denis; Huang, Yong; Bacchetti, Peter; Jin, Chengshi; Gandhi, Monica; Haberer, Jessica E. (AIDS Care, 2015)Current tools for measuring medication adherence have significant limitations, especially among pediatric populations. We conducted a prospective observational study to assess the use of antiretroviral (ARV) drug levels ... -
Association between obesity and combination antiretroviral therapy (cART) adherence among persons with early-stage HIV infection initiating cART
Musinguzi, Nicholas; Stanford, Fatima Cody; Boatin, Adeline A.; Orrell, Catherine; Asiimwe, Stephen; Siedner, Mark; Haberer, Jessica E.; on behalf of the META team (International Journal of Obesity, 2021)Background: Obesity is common among people living with HIV (PLWH) and early-stage infection, yet associations with combination antiretroviral (cART) adherence are unclear. Methods: Among PLWH initiating cART in Uganda ... -
Attenuated HIV-1 Nef But Not Vpu Function in a Cohort of Rwandan Long-Term Survivors
Umviligihozo, Gisele; Mann, Jaclyn K.; Jin, Steven W.; Mwimanzi, Francis M.; Hsieh, Hua-Shiuan A.; Sudderuddin, Hanwei; Lee, Guinevere Q.; Byakwaga, Helen; Muzoora, Conrad; Hunt, Peter W.; Martin, Jeff N.; Haberer, Jessica E.; Karita, Etienne; Allen, Susan; Hunter, Eric; Brumme, Zabrina L.; Brockman, Mark A. (Frontiers in virology, 2022)HIV-1 accessory proteins Nef and Vpu enhance viral pathogenesis through partially overlapping immune evasion activities. Attenuated Nef or Vpu functions have been reported in individuals who display slower disease progression, ... -
Beyond HIV-serodiscordance: Partnership communication dynamics that affect engagement in safer conception care
Matthews, Lynn T.; Burns, Bridget F.; Bajunirwe, Francis; Kabakyenga, Jerome; Bwana, Mwebesa; Ng, Courtney; Kastner, Jasmine; Kembabazi, Annet; Sanyu, Naomi; Kusasira, Adrine; Haberer, Jessica E.; Bangsberg, David R.; Kaida, Angela (PLoS ONE, 2017-09-07)Introduction We explored acceptability and feasibility of safer conception methods among HIV-affected couples in Uganda. Methods We recruited HIV-positive men and women on antiretroviral therapy (ART) (`index') from ... -
Brief report: No association found between traditional healers use and delayed antiretroviral initiation in rural Uganda
Horwitz, Russell H.; Tsai, Alexander C.; Maling, Samuel; Bajunirwe, Francis; Haberer, Jessica E.; Emenyonu, Nneka; Muzoora, Conrad; Hunt, Peter W.; Martin, Jeff N; Bangsberg, David R. (AIDS and Behavior, 2013)Traditional healer and/or spiritual counselor (TH/SC) use has been associated with delays in HIV testing. We examined HIV-infected individuals in southwestern Uganda to test the hypothesis that TH/SC use was also associated ... -
CD4R cell count at antiretroviral therapy initiation and economic restoration in rural Uganda
Venkataramani, Atheendar S.; Thirumurthy, Harsha; Haberer, Jessica E.; II, Yap Boum; Siedner, Mark J.; Kembabazi, Annet; Hunt, Peter W.; Martin, Jeffrey N.; Bangsberg, David R.; Tsai, Alexander C. (Aids, 2014)Objective: To determine whether earlier initiation of antiretroviral therapy (ART) is associated with better economic outcomes. Design: Prospective cohort study of HIV-positive patients on ART in rural Uganda. Methods: ... -
Challenges in using mobile phones for collection of antiretroviral therapy adherence data in a resource-limited setting
Haberer, Jessica E.; Kiwanuka, Julius; Nansera, Denis; Wilson, Ira B.; Bangsberg, David R (AIDS and Behavior, 2010-12)Frequent antiretroviral therapy adherence monitoring could detect incomplete adherence before viral rebound develops and thus potentially prevent treatment failure. Mobile phone technologies make frequent, brief adherence ... -
A combination SMS and transportation reimbursement intervention to improve HIV care following abnormal CD4 test results in rural Uganda: a prospective observational cohort study
Siedner, Mark J.; Santorino, Data; Lankowski, Alexander J.; Kanyesigye, Michael; Bwana, Mwebesa B.; Haberer, Jessica E.; Bangsberg, David R. (BMC medicine, 2015)Background: Up to 50 % of HIV-infected persons in sub-Saharan Africa are lost from care between HIV diagnosis and antiretroviral therapy (ART) initiation. Structural barriers, including cost of transportation to clinic and ... -
Community-based management and care of people with dementia: A training needs assessment among village health teams in Uganda based on WHO guidelines
Karungi, Christine; Obua, Celestino; Rukundo, Godfrey Zari; Maling, Samuel; Haberer, Jessica E.; Wakida, Edith K. (Research square, 2019-10-28)Background: Dementia is a public health problem worldwide with approximately 47 million people living with the disease. Although the symptoms are known and named, dementia remains a hidden problem in low and middle income ... -
Comparison of Self-Reported Alcohol Consumption to Phosphatidylethanol Measurement among HIV-Infected Patients Initiating Antiretroviral Treatment in Southwestern Uganda
Bajunirwe, Francis; Haberer, Jessica E.; Hunt, Peter; Mocello, Rain; Martin, Jeffrey N.; Bangsberg, David R.; Hahn, Judith A.; Boum, Yap (PLoS ONE, 2014-12-01)Background: Alcohol consumption among HIV-infected patients may accelerate HIV disease progression or reduce antiretroviral therapy adherence. Self-reported alcohol use is frequently under-reported due to social desirability ... -
Contraceptive use following unintended pregnancy among Ugandan women living with HIV
Jarolimova, Jana; Kabakyenga, Jerome; Bennett, Kara; Muyindike, Winnie; Kembabazi, Annet; Martin, Jeffrey N.; Hunt, Peter W.; Boum, Yap; Haberer, Jessica E.; Bangsberg, David R.; Kaida, Angela; Matthews, Lynn T. (PLoS ONE, 2018-10-25)Background: Preventing unintended pregnancy is critical for women living with HIV (WLWH) to safely achieve their reproductive goals. Family planning services should support WLWH at risk of repeat unintended pregnancies. ... -
Correction to: Ugandan Study Participants Experience Electronic Monitoring of Antiretroviral Therapy Adherence as Welcomed Pressure to Adhere
Campbell, Jeffrey I.; Eyal, Nir; Musiimenta, Angella; Burns, Bridget; Natukunda, Sylvia; Musinguzi, Nicholas; Haberer, Jessica E. (AIDS and Behavior, 2020)In the original publication of the article, the number of “EAM Users” with education level of “University/vocational” in Table is listed as 5 [12.5%], where it should be listed as 3 [7.5%]. The corrected Table 1 is listed ... -
CYP2B6 Genetic Polymorphisms, Depression, and Viral Suppression in Adults Living with HIV Initiating Efavirenz-Containing Antiretroviral Therapy Regimens in Uganda: Pooled Analysis of Two Prospective Studies
Chang, Jonathan L.; Lee, Sulggi A.; Tsai, Alexander C.; Musinguzi, Nicholas; Muzoora, Conrad; Bwana, Bosco; II, Yap Boum; Haberer, Jessica E.; Hunt, Peter W.; Martin, Jeff; Bangsberg, David R.; Kroetz, Deanna L.; Siedner, Mark J. (AIDS research and human retroviruses, 2018)Single-nucleotide polymorphisms (SNPs) in CYP2B6 have been shown to predict variation in plasma efavirenz concentrations, but associations between these SNPs and efavirenz-mediated depression and viral suppression are less ... -
D-dimer levels and traditional risk factors are associated with incident hypertension among HIV-infected individuals initiating antiretroviral therapy in Uganda
Okello, Samson; Asiimwe, Stephen B.; Kanyesigye, Michael; Muyindike, Winnie R.; Boum, Yap; Mwebesa, Bosco Bwana; Haberer, Jessica E.; Huang, Yong; Williams, Kenneth; Burdo, Tricia H; Tracy, Russell P.; Bangsberg, David R.; Mocello, Rain; Martin, Jeffrey N; Hunt, Peter W.; Siedner, Mark J. (Journal of acquired immune deficiency syndromes, 2016)Objectives-We sought to describe blood pressure changes after antiretroviral therapy (ART) initiation and evaluate the association of markers of inflammation with incident hypertension in a cohort of HIV-individuals in ... -
Declining Prevalence of Probable Depression Among Patients Presenting for Antiretroviral Therapy in Rural Uganda: The Role of Early Treatment Initiation
Chan, Brian T.; Weiser, Sheri D.; Boum, Yap; Haberer, Jessica E.; Kembabazi, Annet; Hunt, Peter W.; Martin, Jeffrey N.; Mocello, A. Rain; Bangsberg, David R.; Tsai, Alexander C. (AIDS and Behavior, 2015)Little is known about trends in depression at antiretroviral therapy (ART) initiation among people living with HIV (PLHIV) in low- and middle-income countries. We used data from an ongoing cohort of treatment-naıve PLHIV ... -
Depression and suicidal ideation among HIV-infected adults receiving efavirenz versus nevirapine in Uganda: a prospective cohort study
Chang, Jonathan L.; Tsai, Alexander C.; Musinguzi, Nicholas; Haberer, Jessica E.; Boum, Yap; Muzoora, Conrad; Bwana, Mwebesa; Martin, Jeffrey N.; Hunt, Peter W.; Bangsberg, David R.; Siedner, Mark J. (Annals of internal medicine, 2018)Background: There is conflicting evidence about potential adverse neuropsychiatric effects of efavirenz and limited data from sub-Saharan Africa, where efavirenz is used as first-line therapy and 70% of people living with ... -
Depression During Pregnancy and the Postpartum Among HIV-Infected Women on Antiretroviral Therapy in Uganda
Kaida, Angela; Matthews, Lynn T.; Ashaba, Scholastic; Tsai, Alexander C.; Kanters, Steve; Robak, Magdalena; Psaros, Christina; Kabakyenga, Jerome; Boum, Yap; Haberer, Jessica E.; Martin, Jeffrey N.; Hunt, Peter W.; Bangsberg, David R. (Journal of acquired immune deficiency syndromes (1999), 67(Suppl 4), S179., 2014-12)Background: Among HIV-infected women, perinatal depression compromises clinical, maternal, and child health outcomes. Antiretroviral therapy (ART) is associated with lower depression symptom severity but the uniformity of ... -
Digital monitoring technologies could enhance tuberculosis medication adherence in Uganda: Mixed methods study
Musiimenta, Angella; Tumuhimbise, Wilson; Mugaba, Aaron T.; Muzoora, Conrad; Houghb, Mari Armstrong; Bangsberg, David; Davis, J. Lucian; Haberer, Jessica E. (Journal of clinical tuberculosis and other mycobacterial diseases, 2019)Background: Effective administration of tuberculosis therapy remains challenging. The recommended strategy of direct observed therapy is challenging and its implementation has been limited in many settings. Digital adherence ...