Faculty of Medicine: Recent submissions
Now showing items 1-20 of 1992
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Malnutrition is a risk factor for tuberculosis disease among household contacts: A case-control study in Uganda
(IJID regions, 2024)Objective: Household contacts (HHCs) of persons with tuberculosis (TB) including rifampicin-resistant or multi drug-resistant TB (RR/MDR-TB) are at risk for TB infection. We investigated whether index patient-level clinical ... -
Self-Rated Competence of Ugandan Healthcare Workers to Obtain Informed Consent for Autopsy
(The American journal of tropical medicine and hygiene, 2024)We examined the self-rated competence of Ugandan healthcare workers (HCWs) in obtaining informed consent for autopsies, considering the challenges of low autopsy acceptance rates globally. In September and October 2023, ... -
The silent threat: investigating the incidence and clinical characteristics of pre-eclampsia and eclampsia in women from tertiary care hospitals of the Democratic Republic of Congo
(Annals of Medicine and Surgery, 2024)Background: Pre-eclampsia and eclampsia are medical conditions that can cause severe complications, such as maternal and foetal morbidity and mortality. This study aimed to assess the incidence and characteristics of ... -
The Future of Kidney Care in Low- and Middle-Income Countries: Challenges, Triumphs, and Opportunities
(Kidney360, 2024)CKD affects about 850 million people worldwide and is projected to be the fifth leading cause of death by 2040. Individuals from low- and middle-income countries (LMICs) bear the bulk of CKD. They face challenges including ... -
Point-of-care urine tenofovir testing to predict HIV drug resistance among individuals with virologic failure
(AIDS, 2023)Objective: We sought to evaluate the utility of a point-of-care (POC) urine tenofovir (TFV) assay, developed to objectively assess adherence, to predict HIV drug resistance (HIVDR) in people failing first-line antiretroviral ... -
FOXP3serum concentration; a likely predictor of CIN and cervical cancer: Secondary analysis from a case control study at a clinic in South western Uganda
(Gynecologic Oncology Reports, 2024)Biomarkers including Forkhead/ winged-helix transcription factor boxP3 have been proposed in immune-histochemical techniques to diagnose cervical lesions, but can be objectively quantified and measured in blood using methods ... -
Impact of supportive supervision visits on the availability of World Health Organization infection prevention and control core components in health facilities in Southwestern Uganda
(Infection Prevention in Practice, 2024)Background: In sub-Saharan Africa, the provision of infection prevention and control (IPC) measures are often limited by resource constraints. Aim: To determine the association of supportive supervision activities with the ... -
Malnutrition and unsuccessful tuberculosis treatment among people with multi-drug resistant tuberculosis in Uganda: A retrospective analysis
(Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2024)Rationale: Multi-drug-resistant tuberculosis (MDR-TB) poses a significant public health challenge to the control and successful eradication of TB globally. Suboptimal treatment outcomes are common among persons with ... -
Evolution of Spatial Risk of Malaria Infection After a Pragmatic Chemoprevention Program in Response to Severe Flooding in Rural Western Uganda
(The Journal of Infectious Diseases, 2024)Background: Malaria epidemics result from extreme precipitation and flooding, which are increasing with global climate change. Local adaptation and mitigation strategies will be essential to prevent excess morbidity and ... -
Perceived Public Participation and Health Delivery in Local Government Districts in Uganda
(International Journal of Environmental Research and Public Health, 2024)Citizen participation is a crucial aspect of the national health system, empowering individuals to contribute to improving local health services through Health Committees (HCs). HCs promote the participation of citizens ... -
Frequency of fungal pathogens in autopsy studies of people who died with HIV in Africa: a scoping review
(Clinical Microbiology and Infection, 2023)Background: Fungal infections are common in HIV-infected individuals and significantly contribute to mortality. However, a substantial number of cases are undiagnosed before death. Objective: To determine the frequency ... -
Influences on Adherence to Antiretroviral Therapy (ART) in Early-Stage HIV Disease: Qualitative Study from Uganda and South Africa
(AIDS and Behavior, 2020)Realization of optimal treatment and prevention benefits in the era of universal antiretroviral therapy (ART) and “U=U” (undetectable = untransmittable) requires high adherence at all stages of HIV disease. This article ... -
Seemingly Unrelated Regression analysis of the Cost and Health-Related Quality of Life Outcomes of the REVAMP randomised clinical trial
(Value in health regional issues, 2023)Objective: To evaluate the nine-month cost and health-related quality of life outcomes of resistance versus viral load testing strategies to manage virological failure in low-middle income countries. Methods: We analysed ... -
Healthcare Workers’ Perspectives on the Utilization of the International HIV Dementia Scale for the Screening HIV-Associated Neurocognitive Disorders: A Qualitative Study at TASO Centres in Central and Southwestern Uganda
(HIV/AIDS-Research and Palliative Care, 2024)Introduction: HIV-associated neurocognitive disorders (HAND) are becoming a significant public health concern in the continuum of human immune virus (HIV) treatment. These disorders range from subtle cognitive impairments ... -
Correlates of HIV treatment adherence selfefficacy among adolescents and young adults living with HIV in southwestern Uganda
(PLOS Global Public Health, 2024)Adherence to antiretroviral therapy (ART) among adolescents and young adults living with HIV (AYLHIV) in sub-Saharan Africa is sub-optimal compared to younger children and older adults. Adherence self-efficacy is one of ... -
Area-Based Socio demographic Factors Associated with Latent Tuberculosis Infection in a Low-Prevalence Setting
(The American Journal of Tropical Medicine and Hygiene, 2023)More than 1 million children and adolescents in the United States are estimated to have latent tuberculosis (TB) infection.1 For the most part, efforts to identify pediatric TB infection in the United States rely upon ... -
Fertility awareness and teenage pregnancy in rural western Uganda: a community-based cross-sectional study
(African Health Sciences, 2023)Background: Teenage pregnancy (pregnancy among girls aged 13-19 years) is prevalent in Uganda but data about the associated factors are limited. Objective: To determine the prevalence and factors associated with teenage ... -
Coping strategies of school-going adolescents during the COVID-19 pandemic in the climate vulnerable Manafwa watershed, Uganda
(BMC psychology, 2024)Background: The COVID-19 pandemic disrupted daily life, economies, and health, prompting strict government measures, including nationwide lockdowns and school closures in Uganda, resulting in significant academic setbacks ... -
Provider perceptions of young people living with HIV and unhealthy alcohol use in Southwestern Uganda: a qualitative study
(Addiction Science & Clinical Practice, 2024)Background: Unhealthy alcohol use is a common public health problem in HIV care settings in Africa and it affects the HIV continuum of care. In Uganda and other low-income countries, HIV care providers are a key resource ... -
Community readiness and acceptance for the implementation of a novel malaria vaccine among at-risk children in sub-saharan Africa: a systematic review protocol
(Malaria Journal, 2024)Background: The World Health Organization novel malaria vaccine for at-risk children has the potential to greatly reduce the current malaria burden in sub-Saharan Africa. However, most studies have reported contradictory ...