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Improving the Specificity of Plasmodium falciparum Malaria Diagnosis in High- Transmission Settings with a Two-Step Rapid Diagnostic Test and Microscopy Algorithm
(Journal of Clinical Microbiology, 2017)
Poor specificity may negatively impact rapid diagnostic test (RDT)-based diagnostic strategies for malaria. We performed real-time PCR on a subset of subjects who had undergone diagnostic testing with a multiple-antigen ...
Quality of care in integrated community case management services in Bugoye, Uganda:a retrospective observational study
(Malaria Journal, 2018)
Background: Village health workers (VHWs) in fve villages in Bugoye subcounty (Kasese District, Uganda) provide
integrated community case management (iCCM) services, in which VHWs evaluate and treat malaria, pneumonia, ...
Private sector drug shops frequently dispense parenteral anti-malarials in a rural region of Western Uganda
(Malaria Journal, 2018)
Background: Malaria is a leading cause of paediatric morbidity and mortality in Uganda. More than half of febrile children in rural areas initially seek care at private clinics and drug shops. These shops are generally ...
Severe Flooding and Malaria Transmission in the Western Ugandan Highlands:
(Journal of infectious diseases, 2016)
Background. There are several mechanisms by which global climate change may impact malaria transmission. We sought to assess how the increased frequency of extreme precipitation events associated with global climate change ...
Anemia was an Uncommon Complication of Severe Malaria in a High-Transmission Rural Area of Western Uganda
(The American journal of tropical medicine and hygiene, 2018)
The clinical epidemiology of severe malaria among patients presenting to peripheral health centers has not been well described. We conducted a prospective, observational cohort study to describe the epidemiology and clinical ...
Impact of rapid diagnostic tests for the diagnosis and treatment of malaria at a peripheral health facility in Western Uganda: an interrupted time series analysis
(Malaria journal, 2015)
Background: The World Health Organization recommends that all suspected malaria cases receive a parasitological diagnosis prior to treatment with artemisinin-based combination therapy. A recent meta-analysis of clinical ...
Who Stays and Who Goes: Predictors of Admission among Patients Presenting with Febrile Illness and a Positive Malaria Rapid Diagnostic Test in a Rural Ugandan Health Center
(The American journal of tropical medicine and hygiene, 2018)
Not much is known about clinical decision-making in rural, low-resource settings regarding fever, a common reason for presentation to care. In this prospective cohort study of patients presenting with febrile illness to a ...
Three-band (HRP-2/pLDH) rapid diagnostic tests for the diagnosis of severe P. falciparum malaria in Western Uganda
(2014)
Mortality among children with severe malaria who receive care at referral centers ranges from 10-30%, and is likely higher among
those presenting to peripheral health facilities.
Using verbal autopsies to estimate under-5 mortality at household level in a rural area of southwestern Uganda: a cross-sectional study
(The Lancet Global Health,, 2018)
In rural Uganda, pediatric deaths that occur outside of health facilities often go unnoticed by the health system, and information on their magnitude and causes remains limited. We aimed to assess the causes of mortality ...