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Incidence of postpartum infection, outcomes and associated risk factors at Mbarara regional referral hospital in Uganda
(BMC pregnancy and childbirth, 2018)
Background: There is a paucity of recent prospective data on the incidence of postpartum infections and associated risk factors in sub-Saharan Africa. Retrospective studies estimate that puerperal sepsis causes approximately ...
Antimicrobial-resistant infections among postpartum women at a Ugandan referral hospital
(PLOS ONE, 2017)
Puerperal sepsis causes 10% of maternal deaths in Africa, but prospective studies on incidence, microbiology and antimicrobial resistance are lacking.
Methods
We performed a prospective cohort study of 4,231 Ugandan women ...
Placental Decidual Arteriopathy and Vascular Endothelial Growth Factor A Expression Among Women With or Without Human Immunodeficiency Virus
(The Journal of Infectious Diseases, 2021)
Background. Women with human immunodeficiency virus (HIV) (WHIV) are at higher risk of adverse birth outcomes. Proposed mechanisms for the increased risk include placental arteriopathy (vasculopathy) and maternal vascular ...
Altered Maternal Antibody Profiles in Women With Human Immunodeficiency Virus Drive Changes in Transplacental Antibody Transfer
(Clinical Infectious Diseases, 2022)
Background: Human immunodeficiency virus (HIV)–exposed, uninfected (HEU) children have a higher risk of severe infection, but the causes are poorly understood. Emerging data point to altered antibody transfer in women with ...
Placental decidual arteriopathy and vascular endothelial growth factor A (VEGF-A) expression among women with and without HIV
(The Journal of Infectious Diseases, 2021)
Background: Women with HIV (WHIV) are at higher risk of adverse birth outcomes. Proposed mechanisms for the increased risk include placental arteriopathy (vasculopathy) and maternal vascular malperfusion (MVM) due to ...
Chronic Placental Inflammation Among Women Living With HIV in Uganda
(ournal of Acquired Immune Deficiency Syndromes, 2020)
Background: HIV-exposed, uninfected (HEU) children have poorer early-life outcomes than HIV-unexposed children. The determinants of adverse health outcomes among HEU children are poorly understood but may result from chronic ...
HIV Infection and risk of postpartum infection, complications and mortality in rural Uganda
(AIDS Care, 2018)
HIV infection may increase risk of postpartum infection and infection-related mortality. We hypothesized that postpartum infection incidence and attributable mortality in Mbarara, Uganda would be higher in HIV-infected ...
Antenatal Care Visit Attendance Frequency and Birth Outcomes in Rural Uganda: A Prospective Cohort Study
(Maternal and Child Health Journal, 2021)
Objectives Antenatal care (ANC) is designed to improve pregnancy outcomes by providing screening and treatment for preventable and treatable diseases. However, data are lacking on whether ANC affects stillbirth risk. We ...