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Improving the Specificity of Plasmodium falciparum Malaria Diagnosis in High- Transmission Settings with a Two-Step Rapid Diagnostic Test and Microscopy Algorithm
(Journal of Clinical Microbiology, 2017)
Poor specificity may negatively impact rapid diagnostic test (RDT)-based diagnostic strategies for malaria. We performed real-time PCR on a subset of subjects who had undergone diagnostic testing with a multiple-antigen ...
Severe Flooding and Malaria Transmission in the Western Ugandan Highlands:
(Journal of infectious diseases, 2016)
Background. There are several mechanisms by which global climate change may impact malaria transmission. We sought to assess how the increased frequency of extreme precipitation events associated with global climate change ...
Impact of rapid diagnostic tests for the diagnosis and treatment of malaria at a peripheral health facility in Western Uganda: an interrupted time series analysis
(Malaria journal, 2015)
Background: The World Health Organization recommends that all suspected malaria cases receive a parasitological diagnosis prior to treatment with artemisinin-based combination therapy. A recent meta-analysis of clinical ...
Who Stays and Who Goes: Predictors of Admission among Patients Presenting with Febrile Illness and a Positive Malaria Rapid Diagnostic Test in a Rural Ugandan Health Center
(The American journal of tropical medicine and hygiene, 2018)
Not much is known about clinical decision-making in rural, low-resource settings regarding fever, a common reason for presentation to care. In this prospective cohort study of patients presenting with febrile illness to a ...