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Association between HRP–2/pLDH rapid diagnostic test band positivity and malaria– related anemia at a peripheral health facility in Western Uganda
(journal of global health, 2015-12)
The detection of severe malaria in resource–constrained settings is often difficult because of requirements for laboratory infrastructure and/or clinical expertise. The aim of this study, therefore, was to explore the ...
Improving the Specificity of Plasmodium falciparum Malaria Diagnosis in High- Transmission Settings with a Two-Step Rapid Diagnostic Test and Microscopy Algorithm
(Journal of Clinical Microbiology, 2017)
Poor specificity may negatively impact rapid diagnostic test (RDT)-based diagnostic strategies for malaria. We performed real-time PCR on a subset of subjects who had undergone diagnostic testing with a multiple-antigen ...
Impact of rapid diagnostic tests for the diagnosis and treatment of malaria at a peripheral health facility in Western Uganda:
(Malaria Journal, 2015)
Background
The World Health Organization recommends that all suspected malaria cases receive a
parasitological diagnosis prior to treatment with artemisin in-based combination therapy. A recent meta-analysis of clinical ...
Practical Implications of the Non-Linear Relationship between the Test Positivity Rate and Malaria Incidence
(PLOS ONE, 2016)
Background: The test positivity rate (TPR), defined as the number of laboratory-confirmed malaria tests per 100 suspected cases examined, is widely used by malaria surveillance programs as one of several key indicators of ...
Private sector drug shops frequently dispense parenteral anti-malarials in a rural region of Western Uganda
(Malaria Journal, 2018)
Background: Malaria is a leading cause of paediatric morbidity and mortality in Uganda. More than half of febrile children in rural areas initially seek care at private clinics and drug shops. These shops are generally ...
Use of a Dual-Antigen Rapid Diagnostic Test to Screen Children for Severe Plasmodium falciparum Malaria in a High-Transmission, Resource-Limited Setting
(Clinical Infectious Diseases, 2017)
Background. In rural areas, many patients with malaria seek care at peripheral health facilities or community case management programs. While this strategy is effective for the management of uncomplicated malaria, severe ...
Severe Flooding and Malaria Transmission in the Western Ugandan Highlands:
(Journal of infectious diseases, 2016)
Background. There are several mechanisms by which global climate change may impact malaria transmission. We sought to assess how the increased frequency of extreme precipitation events associated with global climate change ...
Permethrin‑treated baby wraps for the prevention of malaria: results of a randomized controlled pilot study in rural Uganda
(Malaria Journal, 2022)
Background: Progress against malaria has stalled and may even be slipping backwards in high-burden countries. This is due to a range of factors including insecticide resistance and mosquito feeding behaviours that limit ...
Reuse of malaria rapid diagnostic tests for amplicon deep sequencing to estimate Plasmodium falciparum transmission intensity in western Uganda
(Scientific reports, 2018)
Molecular techniques are not routinely employed for malaria surveillance, while cross-sectional,
community-based parasite surveys require significant resources. Here, we describe a novel use of
malaria rapid diagnostic ...