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Adherence to a six-dose regimen of Artemether-lumefantrine for Treatment of uncomplicated plasmodium falciparum malaria in Uganda

FOGG, CAROLE; BAJUNIRWE, FRANCIS; PIOLA, PATRICE; BIRARO, SAMUEL; CHECCHI, FRANCESCO; KIGULI, JAMES; NAMIIRO, PROSCOVIA; MUSABE, JOY; KYOMUGISHA, AGNES; GUTHMANN, JEAN-PAUL (The American Society of Tropical Medicine and Hygiene, 2004)

Measuring baseline levels of adherence and identifying risk factors for non-adherence are important steps before the introduction of new antimalarials. In Mbarara in southwestern Uganda, we assessed adherence to ...

Assessment of three new parasite lactate dehydrogenase (pan-pLDH) tests for diagnosis of uncomplicated malaria

Fogga, Carole; Twesigye, Rogers; Batwala, Vincent; Piola, Patrice; Nabasumba, Carolyn; Kiguli, James; Mutebi, Frederick; Hook, Christa; Guillerm, Martine; Moody, Anthony; Guthmann, Jean-Paul (Transactions of the Royal Society of Tropical Medicine and Hygiene, 2008)

A study to assess the diagnostic capabilities of three parasite lactate dehydrogenase (pan-pLDH) tests, Vistapan®, CarestartTM and Parabank®, was conducted in Uganda. An HRP2 test, Paracheck-Pf®, and a Giemsa-stained blood ...

Ethno medical knowledge and traditional use of Aristolochia bracteolata Lam. for malaria among local communities in Jubek State of South Sudan: A cross-sectional survey

Mathew, Lina S.; Peter, Emanuel L.; Weisheit, Anke; Tolo, Casim Umba; Deng, Arop L.; Ogwang, Patrick Engeu (Journal of Ethnopharmacology, 2009)

Ethnopharmacological relevance: The recognized challenges to access conventional antimalarial medicines could have contributed to the extensive use of Aristolochia bracteolata Lam. (Aristolochiaceae) to manage malaria in ...

Supervised versus unsupervised intake of sixdose artemether-lumefantrine for treatment of acute, uncomplicated Plasmodium falciparum malaria in Mbarara, Uganda: a randomised trial.

P, Piola; C, Fogg; F, Bajunirwe; S, Biraro; F, Grandesso; E, Ruzagira; J, Babigumira; I, Kigozi; J, Kiguli; J, Kyomuhendo; L, Ferradini; W R J R J, Taylor; F, Checchi; J P, Guthmann (Lancet, 2005)

Background: The six-dose regimen of artemether-lumefantrine is effective and is among combination therapies prioritised to replace antimalarials that no longer work in Africa. However, its effectiveness has not been assessed ...

Artesunate and sulfadoxine-pyrimethamine combinations for the treatment of uncomplicated Plasmodium falciparum malaria in Uganda: a randomized, double-blind, placebo-controlled trial

Priotto, Gerardo; Kabakyenga, Jerome; Pinoges, Loretxu; Ruiz, Aria; Eriksson, Therese; Coussement s, Frangois; Ngambe, Tharcise; Taylor, Walter R. J.; Perea, William; Guthmann, Jean-Paul; Olliaro, Piero; Legros, Dominique (ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2003)

Drug-resistant malaria is spreading in Africa. The few available drugs might be safeguarded if combined with an artemisinin derivative. We investigated the efficacy, safety, and tolerability of 2 combinations of artesunate ...

The Analgesic and Antiplasmodial Activities and Toxicology of Vernonia amygdalina

Njan, Anoka A.; Adzu, Bulus; Agaba, Amon G.; Byarugaba, Dominic; Llera, Silvia Díaz; Bangsberg, David R. (Journal of medicinal food, 2008)

Vernonia amygdalina possesses several bioactive compounds and is used in traditional medicines of southwestern Uganda, along with other regions. Its analgesic potential has not been investigated thus far. The present study ...