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Severe Flooding and Malaria Transmission in the Western Ugandan Highlands:
(Journal of infectious diseases, 2016)
Background. There are several mechanisms by which global climate change may impact malaria transmission. We sought to assess how the increased frequency of extreme precipitation events associated with global climate change ...
Anemia was an Uncommon Complication of Severe Malaria in a High-Transmission Rural Area of Western Uganda
(The American journal of tropical medicine and hygiene, 2018)
The clinical epidemiology of severe malaria among patients presenting to peripheral health centers has not been well described. We conducted a prospective, observational cohort study to describe the epidemiology and clinical ...
Who Stays and Who Goes: Predictors of Admission among Patients Presenting with Febrile Illness and a Positive Malaria Rapid Diagnostic Test in a Rural Ugandan Health Center
(The American journal of tropical medicine and hygiene, 2018)
Not much is known about clinical decision-making in rural, low-resource settings regarding fever, a common reason for presentation to care. In this prospective cohort study of patients presenting with febrile illness to a ...
Female sex and cardiovascular disease risk in rural Uganda: a cross-sectional, population-based study
(BMC cardiovascular disorders, 2019)
Background: Sex-based differences in cardiovascular disease (CVD) burden are widely acknowledged, with male sex considered a risk factor in high-income settings. However, these relationships have not been examined in sub- ...
Timing of Antiretroviral Therapy and Systemic Inflammation in Sub-Saharan Africa: Results From the META Longitudinal Cohort Study
(The Journal of infectious diseases, 2019)
Chronic inflammation predicts complications in persons with human immunodeficiency virus infection. We compared D-dimer, soluble CD14, and interleukin 6 levels before and 12 months after antiretroviral therapy (ART) ...
Inflammatory biomarkers prior to antiretroviral therapy as prognostic markers of 12-month mortality in South Africa and Uganda
(AIDS, 2019)
Objective: The aim of this study was to determine the utility of biomarkers of immune activation, systemic inflammation and coagulopathy prior to antiretroviral therapy to predict mortality during the first year of ...
Antenatal Care Visit Attendance Frequency and Birth Outcomes in Rural Uganda: A Prospective Cohort Study
(Maternal and Child Health Journal, 2021)
Objectives Antenatal care (ANC) is designed to improve pregnancy outcomes by providing screening and treatment for preventable and treatable diseases. However, data are lacking on whether ANC affects stillbirth risk. We ...
Prevalence and Correlates of Cardiovascular Autonomic Neuropathy Among Patients with Diabetes in Uganda: A Hospital-Based Cross-sectional Study
(Global Heart, 2020)
Background: Cardiovascular autonomic neuropathy (CAN) is a common complication in individuals with diabetes mellitus (DM) but often overlooked in clinical practice. The burden and correlates of CAN have not been extensively ...
Postural changes in blood pressure among patients with diabetes attending a referral hospital in southwestern Uganda: a cross‑sectional study
(BMC Cardiovascular Disord, 2021)
Background: Orthostatic hypotension (OH) and orthostatic hypertension (OHT) are often unrecognized in clinical care for diabetic individuals, yet they are associated with increased risk for adverse cardiovascular outcomes. ...
High prevalence of prolonged QTc interval among individuals in ambulatory diabetic care in southwestern Uganda
(International Journal of Diabetes in Developing Countries, 2021)
Background: Heart rate-corrected QT (QTc) interval is associated with increased risk for cardiovascular events and mortality among individuals with diabetes mellitus (DM). Little is known about the epidemiology of prolonged ...