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Supervised versus unsupervised intake of sixdose artemether-lumefantrine for treatment of acute, uncomplicated Plasmodium falciparum malaria in Mbarara, Uganda: a randomised trial.
(Lancet, 2005)
Background: The six-dose regimen of artemether-lumefantrine is effective and is among combination therapies prioritised to replace antimalarials that no longer work in Africa. However, its effectiveness has not been assessed ...
Prevalence and specificities of red blood cell alloantibodies in transfused Ugandans with different diseases
(Vox sanguinis, 2010)
Background and Objectives Alloantibody formation against red blood cell (RBC) antigens is a common complication of transfusion therapy. However, the prevalence of RBC alloimmunization is hardly known in Black Africans. In ...
Dried-leaf Artemisia annua: A practical malaria therapeutic for developing countries?
(World journal of pharmacology, 2014-12)
Artemisinin from the plant Artemisia annua (A. annua) L, and used as artemisinin combination therapy (ACT), is the current best therapeutic for treating malaria, a disease that hits children and adults especially in ...
Malaria is an uncommon cause of adult sepsis in south-western Uganda
(Malaria Journal, 2013-05-01)
Background: Malaria is often considered a cause of adult sepsis in malaria endemic areas. However, diagnostic limitations can make distinction between malaria and other infections challenging. Therefore, the objective of ...
Population pharmacokinetics of artemether and dihydroartemisinin in pregnant women with uncomplicated plasmodium falciparum malaria in uganda
(Malaria Journal, 2012-08-22)
Background: Malaria in pregnancy increases the risk of maternal anemia, abortion and low birth weight.
Approximately 85.3 million pregnancies occur annually in areas with Plasmodium falciparum transmission.
Pregnancy ...
Artesunate and sulfadoxine-pyrimethamine combinations for the treatment of uncomplicated Plasmodium falciparum malaria in Uganda: a randomized, double-blind, placebo-controlled trial
(ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 2003)
Drug-resistant malaria is spreading in Africa. The few available drugs might be safeguarded if combined
with an artemisinin derivative. We investigated the efficacy, safety, and tolerability of 2 combinations of
artesunate ...
Dried-leaf Artemisia annua: A practical malaria therapeutic for developing countries?
(World journal of pharmacology,, 2014)
Artemisinin from the plant Artemisia annua (A. annua) L., and used as artemisinin combination therapy (ACT), is the current best therapeutic for treating malaria, a disease that hits children and adults especially in ...
Permethrin‑treated baby wraps for the prevention of malaria: results of a randomized controlled pilot study in rural Uganda
(Malaria Journal, 2022)
Background: Progress against malaria has stalled and may even be slipping backwards in high-burden countries. This is due to a range of factors including insecticide resistance and mosquito feeding behaviours that limit ...
Are rapid diagnostic tests more accurate in diagnosis of malaria compared to microscopy?
(Malaria Journal, 2010)
Background
Prompt, accurate diagnosis and treatment with artemisinin combination therapy remains vital to current malaria control. Blood film microscopy the current standard test for diagnosis of malaria has several ...
Reuse of malaria rapid diagnostic tests for amplicon deep sequencing to estimate Plasmodium falciparum transmission intensity in western Uganda
(Scientific reports, 2018)
Molecular techniques are not routinely employed for malaria surveillance, while cross-sectional,
community-based parasite surveys require significant resources. Here, we describe a novel use of
malaria rapid diagnostic ...