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SARS-CoV-2 vaccine development
(Coronavirus Drug Discovery, 2022)
Vaccine development is the entire process involved in the designing of a vaccine to the post release study period. Vaccines work against viruses, bacteria, fungi and parasites. The design in which an antiviral vaccine is ...
Pharmacognostic and phytochemical studies as an invaluable approach for correct identification of medicinal plants: The case of Artemisia vulgaris L. substituted for Artemisia annua L. in Western Uganda
(TMR Integrative Medicine, 2023)
Different parts of Artemisia vulgaris L. (A. vulgaris) are ethno-medicinally used as an emmenagogue and for the treatment of ailments such as malaria fever, ulcers, and cancer. However, anecdotal evidence shows that the ...
Chromatographic, Mass and Cytotoxicity analysis of Isolates from Eichhornia crassipes’ Roots and Leaves against HepG2 and MCF7 cell lines
(Cogent Biology, 2021)
Cancers remain one of the leading causes of death in the world. However, known conventional cancer medicines remain scarce, expensive and out of reach to many patients. To provide an alternative for the expensive therapies, ...
Fundamental Methods in Drug Permeability, pKa, LogP and LogDx Determination
(Journal of Drug Research and Development, 2018)
Potential drug molecular leads from plants are usually tested for their efficacy in bioactivity assays in preclinical trials. This is followed by testing for the properties of the molecular structures, if they can be ...
Safety and Efficacy of Medicinal Plants Used to Manufacture Herbal Products with Regulatory Approval in Uganda: A Cross-Sectional Study
(Evidence-Based Complementary and Alternative Medicine, 2022)
Introduction: Uganda National Drug Authority requires phytochemical screening, freedom from microbial contamination, and evidence of safety and efficacy of the constituent plants to register herbal products. Since Uganda ...
Therapeutic potentials of Vachellia nilotica (L.) extracts in Hepatitis C infection: A review
(Scientific African, 2021)
Hepatitis C Virus (HCV) infection represents a huge burden on healthcare systems world- wide. Vachellia nilotica ( V. nilotica ) is a widely used plant specie in folk medicine for viral diseases and in some communities for ...
Ethnotherapeutic Uses and Phytochemical Composition of Physalis peruviana L.: An Overview
(The Scientific World Journal, 2021)
Background: Plant-derived medicines are widespread and continue to increase in traditional and modern medicine, especially in developing countries. Physalis peruviana L. is among the most used plants in conventional ...
Ethno medical knowledge and traditional use of Aristolochia bracteolata Lam. for malaria among local communities in Jubek State of South Sudan: A cross-sectional survey
(Journal of Ethnopharmacology, 2009)
Ethnopharmacological relevance: The recognized challenges to access conventional antimalarial medicines could have contributed to the extensive use of Aristolochia bracteolata Lam. (Aristolochiaceae) to manage malaria in ...
Antidiabetic Medicinal Plants Used in Democratic Republic of Congo: A Critical Review of Ethnopharmacology and Bioactivity Data
(Frontiers in Pharmacology, 2021-10-27)
Several studies have been conducted and published on medicinal plants used to manage Diabetes Mellitus worldwide. It is of great interest to review available studies from a country or a region to resort to similarities/d ...
Potential benefits of antiviral African medicinal plants in the management of Viral infections
(Frontiers in Pharmacology, 2021-12-24)
Background: Viruses cause various human diseases, some of which become pandemic
outbreaks. This study synthesized evidence on antiviral medicinal plants in Africa which
could potentially be further studied for viral ...