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High Mobility Group Box 1 (HMGB1) and HIV-Associated Kaposi’s Sarcoma in Africa
(Academia.edu, 2015)
Other than Kaposi’s sarcoma-associated herpesvirus (KSHV) and CD4+ T cell lymphopenia, the mechanisms responsible for KS are poorly understood. Additional mechanisms must exist in sub-Saharan Africa given that only a ...
Food insecurity, depression and the modifying role of social support among people living with HIV/AIDS in rural Uganda
(Social science & medicine, 2012)
Depression is common among people living with HIV/AIDS and contributes to a wide range of worsened HIV-related outcomes, including AIDS-related mortality. Targeting modifiable causes of depression, either through primary ...
How Does Antiretroviral Treatment Attenuate the Stigma of HIV? Evidence from a Cohort Study in Rural Uganda
(AIDS and Behavior, 2013)
Program implementers and qualitative researchers have described how increasing availability of
HIV antiretroviral therapy (ART) is associated with improvements in psychosocial health and internalized stigma. To determine ...
Variation in HIV-1 Nef function within and among viral subtypes reveals genetically separable antagonism of SERINC3 and SERINC5
(PLoS pathogens, 2020)
HIV Nef counteracts cellular host restriction factors SERINC3 and SERINC5, but our understanding of how naturally occurring global Nef sequence diversity impacts these activities is
limited. Here, we quantify SERINC3 and ...
Timing of Antiretroviral Therapy and Systemic Inflammation in Sub-Saharan Africa: Results From the META Longitudinal Cohort Study
(The Journal of infectious diseases, 2019)
Chronic inflammation predicts complications in persons with human immunodeficiency virus infection. We compared D-dimer, soluble CD14, and interleukin 6 levels before and 12 months after antiretroviral therapy (ART) ...
How Does Antiretroviral Treatment Attenuate the Stigma of HIV? Evidence from a Cohort Study in Rural Uganda
(AIDS and Behavior, 2013)
Program implementers and qualitative researchers have described how increasing availability of HIV antiretroviral therapy (ART) is associated with improvements in psychosocial health and internalized
stigma. To determine ...
GPS-measured distance to clinic, but not self-reported transportation factors, are associated with missed HIV clinic visits in rural Uganda
(AIDS, 2013)
Objective—Studies of the association between transportation barriers and HIV-related health
outcomes have shown both positive and negative effects, possibly because a reliable, validated
measure of transportation barriers ...
Ideal Cardiovascular Health and Carotid Atherosclerosis in a Mixed Cohort of HIV-Infected and Uninfected Ugandans
(2017)
Preventable cardiovascular disease (CVD) risk factors are responsible for the majority of CVD-related deaths, and are increasingly recognized as a cause of morbidity and mortality for HIV-infected persons taking antiretroviral ...
Association of Gut Intestinal Integrity and Inflammation with Insulin Resistance in Adults Living with HIV in Uganda
(AIDS Patient Care and STDs, 2019)
We conducted a cross-sectional study of 148 HIV+ on HIV antiretroviral therapy and 149 HIV- adults in Mbarara, Uganda, to estimate the association between HIV infection and homeostasis model assessment of insulin resistance ...
Genotypic and Mechanistic Characterization of Subtype- Specific HIV Adaptation to Host Cellular Immunity
(Journal of virology, 2018)
The extent to which viral genetic context influences HIV adaptation to human leukocyte antigen (HLA) class I-restricted immune pressures remains incompletely understood. The Ugandan HIV epidemic, where major pandemic group ...