Browsing Research Articles by Title
Now showing items 142-161 of 224
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No Association Found Between Traditional Healer Use and Delayed Antiretroviral Initiation in Rural Uganda
(AIDS and Behavior, 2013)Traditional healer and/or spiritual counselor (TH/SC) use has been associated with delays in HIV testing. We examined HIV-infected individuals in southwestern Uganda to test the hypothesis that TH/SC use was also associated ... -
Non-R5-tropic HIV-1 in Subtype A1 and D Infections Were Associated with Lower Pre-therapy CD4 Count But Not with PI/(N)NRTI Therapy Outcomes in Mbarara, Uganda
(AIDS, 2016)Background: Previous studies suggest that infection with non-R5-tropic subtype B HIV-1, compared to R5, is associated with a more rapid decline in CD4 count, but does not affect PI/(N)NRTI therapy outcome. Here, we explored ... -
Obstructive lung disease and quality of life after cure of multi-drug-resistant tuberculosis in Uganda: a cross-sectional study
(Tropical medicine and health, 2020)Background: Pulmonary multi-drug-resistant tuberculosis (MDR TB) alters lung architecture and involves lengthy treatment duration, high pill burden, drug adverse effects, travel restrictions, and stigma. Literature about ... -
One-year incidence and standardized mortality rates for esophageal squamous cell carcinoma in Uganda
(2021)Background: Little is known about the survival of patients with esophageal squamous cell cancer in resource limited settings. Objectives: We sought to determine the incidence of one-year all-cause mortality and ... -
Opportunities to harness technology to deliver HIV Prevention / healthy sexuality programming to sexual and gender minority adults living in East Africa
(Springer Nature, 2020-10-29)Debido a la estigmatización y discriminación contra lesbianas, gays, bisexuales, transgénero y otras personas de minorías sexuales y de género en África Oriental, hay limitadas investigaciones sobre salud sexual centradas ... -
Optimisation of the Medical Education Partnership Initiative to address African health-care challenges
(Lancet Glob Health, 2015)The Medical Education Partnership Initiative (MEPI) is an innovative and potentially transformative 5-year programme, established by the US Government in 2010, to increase the number of doctors to meet crucial human resource ... -
Optimizing Network Connectivity for Mobile Health Technologies in sub-Saharan Africa
(PLoS ONE, 2012)Background: Mobile health (mHealth) technologies hold incredible promise to improve healthcare delivery in resource limited settings. Network reliability across large catchment areas can be a major challenge. We performed ... -
Outcomes of patients with severe infection in Uganda according to adherence to the World Health Organization's Integrated Management of Adolescent and Adult Illness fluid resuscitation guidelines
(Journal of Critical Care, 2017)Purpose: We determined outcomes in hospitalized patients in Uganda with World Health Organization's Integrated Management of Adolescent and Adult Illness (IMAI) defined septic shock (IMAI-shock) or severe respiratory ... -
Outpatient Cryptococcal Antigen Screening Is Associated With Favorable Baseline Characteristics and Improved Survival in Persons With Cryptococcal Meningitis in Uganda
(Clinical Infectious Diseases, 2023)Background: It is unknown whether persons with symptomatic cryptococcal meningitis detected during routine blood cryptococcal antigen (CrAg) screening have better survival than persons presenting with overt meningitis. ... -
Patient choice improves self-efficacy and intention to complete tuberculosis preventive therapy in a routine HIV program setting in Uganda
(PLoS One, 2021)A 12-dose weekly regimen of rifapentine plus isoniazid (3HP) is recommended for the prevention of active tuberculosis (TB); however, it is unclear whether 3HP should be provided by directly observed therapy (DOT) or ... -
Patient-provider experiences with chronic non-communicable disease care during COVID-19 lockdowns in rural Uganda: A qualitative analysis
(Plos one, 2023)Non-communicable diseases (NCDs) are a growing health burden in Sub-Saharan Africa and especially Uganda, where they account for over one third of all deaths. During the COVID-19 pandemic, public health control measures ... -
Perceived barriers and facilitators to antiretroviral therapy adherence among youth aged 15-24 years at a regional HIV clinic in SouthWestern Uganda: a qualitative study
(African Health Sciences, 2022)Introduction: South-Western region has the second highest HIV prevalence in Uganda. Youth aged 15-24 have shown poor adherence to antiretroviral therapy compared to the older cohorts. Previous studies from other regions ... -
Performance of a histidine-rich protein 2 rapid diagnostic test, paracheck pf ® , for detection of malaria infections in Ugandan pregnant women
(The American Society of Tropical Medicine and Hygiene, 2012)Improved laboratory diagnosis is critical to reduce the burden of malaria in pregnancy. Peripheral blood smears appear less sensitive than Plasmodium falciparum histidine-rich protein 2–based rapid diagnostic tests (RDTs) ... -
Persistently elevated intracranial pressure in cryptococcal meningitis– 76 therapeutic lumbar punctures
(Medical Mycology Case Reports, 2023)Cryptococcal meningitis still remains the most common form of adult meningitis in sub-Saharan Africa, due to the burden of HIV/AIDS. Increased intracranial pressure (ICP) is a major complication of cryptococcosis and ... -
Point-of-Care C-Reactive Protein Testing to Facilitate Implementation of Isoniazid Preventive Therapy for People Living with HIV
(Journal of acquired immune deficiency syndromes, 2014)Background—Symptom-based tuberculosis screening identifies less than one-third of eligible HIV-infected patients as candidates for isoniazid preventive therapy (IPT). We evaluated whether testing for C-reactive protein ... -
Point-of-Care Diagnosis and Prognostication of Cryptococcal Meningitis With the Cryptococcal Antigen Lateral Flow Assay on Cerebrospinal Fluid
(Oxford University Press, 2013)The cryptococcal antigen (CRAG) lateral flow assay (LFA) had 100% sensitivity and specificity on cerebrospinal fluid samples. Pretreatment LFA titers correlated with quantitative cultures (R2 = 0.7) and predicted 2- and ... -
Population attributable fraction of esophageal squamous cell carcinoma due to smoking and alcohol in Uganda
(BMC Cancer, 2016)Background: Despite the high rates and regional variation of esophageal squamous cell carcinoma (ESCC) in East Africa, the contributions of smoking and alcohol to the ESCC burden in the general population are unknown. ... -
Population Pharmacokinetics and Significant Under-Dosing of Anti-Tuberculosis Medications in People with HIV and Critical Illness
(Antibiotics, 2021)Critical illness from tuberculosis (TB) bloodstream infection results in a high case fatality rate for people living with human immunodeficiency virus (HIV). Critical illness can lead to altered pharmacokinetics and ... -
Positive Deviance for Dual-Method Promotion among Women in Uganda: A Qualitative Study
(International journal of environmental research and public health, 2020-07-12)Dual-method use is the most reliable form of protection against unintended pregnancies and human immunodeficiency virus/sexually transmitted infections (HIV/STIs). Although dual-method use remains uncommon among women in ... -
Post-traumatic stress disorder among persons with HIV who engage in heavy alcohol consumption in southwestern Uganda
(BMC psychiatry, 2021)Background: We aimed to describe the prevalence of PTSD symptoms and its associated factors in persons living with HIV (PLWH) in Uganda who engage in heavy alcohol use. Methods: We analyzed baseline data from the Drinkers ...