Browsing Research articles by Title

Now showing items 1-20 of 38

    • Bilateral Candida keratitis in an HIV patient with asymptomatic genitourinary candidiasis in Uganda 

      Arunga, Simon; Kwaga, Teddy; Leck, Astrid; Hu, Victor H.; Burton, Matthew J. (Medical Mycology Case Reports, 2018-07-17)
      A 35-year-old male presented with Candida keratitis in the left eye. He was HIV positive with a CD4 of 352 cells/ μL. The eye quickly deteriorated, despite intensive antifungal treatment and was eviscerated. Five months ...

    • Changing ophthalmic practice during the COVID-19 pandemic in Uganda 

      Kanji, Raheel Rizwan; Arunga, Simon (Community Eye Health, 2020)

    • Chlorhexidine gluconate 0.2% as a treatment for recalcitrant fungal keratitis in Uganda: a pilot study 

      Arunga, Simon; Mbarak, Tumu; Ebong, Abel; Mwesigye, James; Kuguminkiriza, Dan; Ahmed, Abeer H A Mohamed; Hoffman, Jeremy John; Leck, Astrid; Hu, Victor; Burton, Matthew (Arunga, S., Mbarak, T., Ebong, A., Mwesigye, J., Kuguminkiriza, D., Mohamed, A., ... & Burton, M. (2021). Chlorhexidine gluconate 0.2% as a treatment for recalcitrant fungal keratitis in Uganda: a pilot study. BMJ open ophthalmology, 6(1), e000698., 2021-07-05)
      Objective: Fungal keratitis is a major ophthalmic public health problem, particularly in low-income and middle-income countries. The options for treating fungal keratitis are limited. Our study aimed to describe the ...

    • The clinical presentation and outcome of Mooren’s ulcer at Ruharo Eye Centre, Southwestern Uganda; a hospital based retrospective study 

      D, Kavuma; Simon, Arunga (Journal of Ophthalmology of Eastern Central and Southern Africa, 2016-12)
      Objective: To describe the clinical presentation, management, and treatment outcomes of Mooren’s ulcer in Uganda. Methods: We reviewed records of all patients diagnosed with Mooren’s ulcer at Ruharo Eye Centre from January ...

    • Corneal endothelial cell density and associated factors among adults at a regional referral hospital in Uganda: a crosssectional study 

      Namwase, Shamiim ;  Ruvuma, Sam; Onyango, John ; Kwaga, Teddy ; Ebong, Abel ;  Atwine, Daniel;  Mukunya, David; Arunga, Simon  (BMC ophthalmology, 2024)
      Background: To assess the prevalence of low corneal endothelial cell density and correlates of corneal endothelial cell density among adults attending Mbarara University and Referral Hospital Eye Centre in Uganda. Methods: ...

    • Delay Along the Care Seeking Journey of Patients with Microbial Keratitis in Uganda 

      Arunga, Simon; Kintoki, Guyguy M.; Gichuhi, Stephen; Onyango, John; Newton, Rob; Leck, Astrid; Macleod, David; Hu, Victor H.; Burton, Matthew J. (Ophthalmic epidemiology, 2019)
      Purpose: To describe the care seeking journey and causes of delay among patients with Microbial Keratitis in Uganda. Methods: A prospective cohort of patients presenting with microbial keratitis at the two main eye units ...

    • Delay in accessing definitive care for patients with microbial keratitis in Nepal 

      Hoffman, Jeremy J.; Yadav, Reena; Sanyam, Sandip Das; Chaudhary, Pankaj; Roshan, Abhishek; Singh, Sanjay K.; Mishra, Sailesh K.; Arunga, Simon; Hu, Victor H.; Macleod, David; Leck, Astrid; Burton, Matthew J. (Frontiers in medicine, 2022)
      Background: The aim of this study was to describe the health-seeking journey for patients with microbial keratitis (MK) in Nepal and identify factors associated with delay. Methods: Prospective cohort study where MK ...

    • Diagnosis of Fungal Keratitis in Low-Income Countries: Evaluation of Smear Microscopy, Culture, and In Vivo Confocal Microscopy in Nepal 

      Hoffman, Jeremy J.; Yadav, Reena; Sanyam, Sandip Das; Chaudhary, Pankaj; Roshan, Abhishek; Singh, Sanjay Kumar; Arunga, Simon; Hu, Victor H.; Macleod, David; Leck, Astrid; Burton, Matthew J. (Journal of Fungi, 2022)
      Clinically diagnosing fungal keratitis (FK) is challenging; diagnosis can be assisted by investigations including in vivo confocal microscopy (IVCM), smear microscopy, and culture. The aim of this study was to estimate the ...

    • Diurnal intraocular pressure fluctuation in black adult primary open angle glaucoma patients attending Ruharo Eye Centre, South- Western Uganda 

      Simon, Arunga; FM, Bwetsia; L, Aliraki (Journal of Ophthalmology of Eastern Central and Southern Africa, 2014-07)
      Objective: To study the general diurnal intraocular pressure (IOP) fluctuation in black adult patients with Primary Open Angle Glaucoma attending Ruharo Eye Centre; to determine their IOP fluctuation range and determine ...

    • Emergency management: microbial keratitis 

      Arunga, Simon; Burton, Matthew; Arinda, Gilbert (Community eye health, 2018)

    • Epidemiology of Microbial Keratitis in Uganda: A Cohort Study 

      Arunga, Simon; Kintoki, Guyguy M.; Mwesigye, James; Ayebazibwe, Bosco; Onyango, John; Bazira, Joel; Newton, Rob; Gichuhi, Stephen; Lecka, Astrid; Macleod, David; Hua, Victor H.; Burton, Matthew J. (Ophthalmic epidemiology, 2020)
      Purpose: To describe the epidemiology of Microbial Keratitis (MK) in Uganda. Methods: We prospectively recruited patients presenting with MK at two main eye units in Southern Uganda between December 2016 and March 2018. ...

    • Experiences and Perceptions of Ophthalmic Simulation-Based Surgical Education in Sub-Saharan Africa 

      Annoh, Roxanne; Banks, Lena Morgon; Gichuhi, Stephen; Buchan, John; Makupa, William; Otiti, Juliet; Arunga, Simon; Burton, Matthew J.; Dean, William H. (. Journal of surgical education, 2021)
      BACKGROUND: Simulation-based surgical education (SBSE) can positively impact trainee surgical competence. However, a detailed qualitative study of the role of simulation in ophthalmic surgical education has not previously ...

    • Eye care where there are no ophthalmologists: the Uganda experience 

      Magyezi, Joseph; Arunga, Simon (Community Eye Health, 2020)

    • Going beyond the means: Exploring the role of bias from digital determinants of health in technologies 

      Charpignon, Marie-Laure; Carrel, Adrien; Jiang, Yihang; Kwaga, Teddy; Cantada, Beatriz; Hyslop, Terry; Cox, Christopher E.; Haines, Krista; Koomson, Valencia; Dumas, Guillaume; Morley, Michael; Dunn, Jessilyn; Wong, An- Kwok Ian (PLOS Digital Health, 2023)
      Background: In light of recent retrospective studies revealing evidence of disparities in access to medical technology and of bias in measurements, this narrative review assesses digital determinants of health (DDoH) in ...

    • HIV and the eye 

      Gichuhi, Stephen; Arunga, Simon (Community eye health, 2020)

    • How to make fluorescein strips 

      Arinda, Gilbert; Arunga, Simon (Community Eye Health Journal, 2018)
      Fluorescein strips are an essential diagnostic tool in eye care. They are useful for performing a number of procedures, such as measuring intraocular pressure, assessing dry eye and detecting corneal abrasions. Unfortunately, ...

    • The impact of microbial keratitis on quality of life in Uganda 

      Arunga, Simon; Wiafe, Geoffrey; Habtamu, Esmael; Onyango, John; Gichuhi, Stephen; Leck, Astrid; Macleod, David; Hu, Victor; Burton, Matthew (BMJ Open Ophthalmology, 2019-12-23)
      Background: Microbial keratitis (MK) is a frequent cause of sight loss in sub-Saharan Africa. However, no studies have formally measured its impact on quality of life (QoL) in this context. Methods: As part of a nested ...

    • The impact of simulation-based trabeculectomy training on resident core surgical skill competenc 

      Annoh, Roxanne; Buchan, John; Gichuhi, Stephen; Philippin, Heiko; Arunga, Simon; Mukome, Agrippa; Admassu, Fisseha; Lewis, Karinya; Makupa, William; Otiti-Sengeri, Juliet; Kim, Min; MacLeod, David; Burton, Matthew J.; Dean, William H. (Journal of glaucoma, 2023)
      Purpose: To measure the impact of trabeculectomy surgical simulation training on core surgical skill competency in resident ophthalmologists. Methods: This is a post-hoc analysis of the GLAucoma Simulated Surgery (GLASS) ...

    • Improving survival of retinoblastoma in Uganda 

      Waddell, Keith M; Kagame, Kenneth; Ndamira, Andrew; Twinamasiko, Amos; Picton, Susan V; Simmons, Ian G; Revill, Paul; Johnston, W Tom; Newton, Robert (British Journal of Ophthalmology, 2015-01-21)
      Background: Diagnostic delay results in relatively high mortality among children with retinoblastoma in Uganda, where treatment was limited to surgery and, for some, radiotherapy. In order to improve outcomes, a simple ...

    • Intense Simulation-Based Surgical Education for Manual Small-Incision Cataract Surgery 

      Dean, William H.; Gichuhi, Stephen; Buchan, John C.; Makupa, William; Mukome, Agrippa; Otiti-Sengeri, Juliet; Arunga, Simon; Mukherjee, Subhashis; Kim, Min J.; Harrison-Williams, Lloyd; MacLeod, David; Cook, Colin; Burton, Matthew J. (JAMA Ophthalmology, 2020-11-05)
      Importance: Cataracts account for 40% of cases of blindness globally, with surgery the only treatment. Objective: To determine whether adding simulation-based cataract surgical training to conventional training results ...