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Lowenstein-Jensen Selective Medium for Reducing Contamination in Mycobacterium tuberculosis Culture
(JCM, 214-07)
We compared Mycobacterium tuberculosis sputum culture recovery and contamination rates between Lowenstein-Jensenmedium(LJ)containing the following decontaminants and LJalone:(i)PANTA(n 299),(ii) Selectatab-MB(n 299),and(iii) ...
MinION Whole-Genome Sequencing in Resource-Limited Settings: Challenges and Opportunities
(Current Clinical Microbiology Reports, 2022-11)
Purpose of Review The introduction of MinION whole-genome sequencing technology greatly increased and simplified complete genome sequencing in various fields of science across the globe. Sequences have been generated from ...
Anti-Mycobacterial Activity of Medicinal Plant Extracts Used in the Treatment of Tuberculosis by Traditional Medicine Practitioners in Uganda
(Pharmacology & Pharmacy, 2023)
Tuberculosis (TB) remains a public health challenge and one of the leading causes of death worldwide. TB is preventable and curable. However, treatment of tuberculosis has continued to be difficult as a result of rapid ...
Unravelling patient pathways in the context of antibacterial resistance in East Africa
(Research square, 2022)
Background: A key factor driving the development and maintenance of antibacterial resistance (ABR) is individuals’ use of antibiotics (ABs) to treat illness. It is therefore crucial to understand the dynamics of patient ...
Good Utilization, Low Completion Rates of Early Infant HIV Diagnostic Services at a District Hospital in Rural South Western Uganda
(Research square, 2022-03-02)
Introduction: Early Infant Diagnosis (EID) using DNA PCR has been utilized in the diagnosis of HIV
worldwide. This study aimed to determine the utilization of EID using DNA PCR.
Methods: A mixed methods study involving ...
Paenibacillus spp infection among infants with postinfectious hydrocephalus in Uganda: an observational case-control study
(The Lancet Microbe, 2023)
Background: Paenibacillus thiaminolyticus is a cause of postinfectious hydrocephalus among Ugandan infants. To determine whether Paenibacillus spp is a pathogen in neonatal sepsis, meningitis, and postinfectious hydrocephalus, ...
Cryptococcus neoformans Genotypic Diversity and Disease Outcome among HIV Patients in Africa
(Journal of Fungi, 2022)
Cryptococcal meningoencephalitis, a disease with poor patient outcomes, remains the most prevalent invasive fungal infection worldwide, accounting for approximately 180,000 deaths each
year. In several areas of sub-Saharan ...
Prevalence of Nasal Carriage of Methicillin Resistant Staphylococcus aureus among Patients, Health Care Workers and Patients’ Care Takers at Kabale Regional Referral Hospital, South Western Uganda
(Research square, 2023)
Background: Methicillin Resistant Staphylococcus aureus (MRSA) is a type of Gram-positive bacterium that is genetically different from other strains of Staphylococcus aureus by virtue its capability to overcome the actions ...
Umbilical Stump Colonization and Antibiotic Susceptibility Patterns of Bacteria from Umbilical Stumps of Neonates Admitted at Holy Innocents Children’s Hospital, Mbarara, South Western Uganda
(Research square, 2023)
Introduction: Every year a million deaths of neonates occur worldwide due to bacteria that has ascended through the umbilical stump leading to serious infection. An umbilical stump that has just separated is known to be ...