Browsing Research Article by Title
Now showing items 62-81 of 123
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Human Health Risk Assessment of Heavy Metals in Kampala (Uganda) Drinking Water
(Journal of Food Research, 2022)Levels of aluminium, arsenic, cadmium, chromium, copper, iron, mercury, manganese, nickel, lead and zinc in tap water, groundwater-fed protected spring and bottled water were determined. The cancer and non-cancer risks ... -
Human Health Risk Assessment of Heavy Metals in Kampala (Uganda) Drinking Water
(Journal of Food Research, 2022)Levels of aluminium, arsenic, cadmium, chromium, copper, iron, mercury, manganese, nickel, lead and zinc in tap water, groundwater-fed protected spring and bottled water were determined. The cancer and non-cancer risks ... -
Hypoglycemic, Antihyperglycemic, and Toxic Effects of Physalis peruviana L. Aqueous and Methanolic Leaf Extracts in Wistar Rats
(Journal of Experimental Pharmacology, 2022)Background: Physalis peruviana L. (Solanaceae) is a plant widely used in traditional medicine systems to manage various diseases, including diabetes mellitus, which remains a global health problem in developing and developed ... -
Identification of Antimicrobial Peptides Isolated From the Skin Mucus of African Catfish, Clarias gariepinus (Burchell, 1822)
(Frontiers in microbiology, 2021)Antimicrobial peptides (AMPs) constitute a broad range of bioactive compounds in diverse organisms, including fish. They are effector molecules for the innate immune response, against pathogens, tissue damage and infections. ... -
Impact of Sex: Determination of Alcohol Neuroadaptation and Reinforcement
(ALCHOLISM,Clinical and experimental Research, 2006-01-25)his article represents the proceedings of a symposium at the Research Society on Alcoholism meeting in Santa Barbara, California. The organizers/chairs were Kristine M. Wiren and Deborah A. Finn. Following a brief introduction ... -
In vitro anti-tuberculous study on the combination of extracts of stem-bark of Erythrina abyssinica Lam. ex DC and conventional drugs
(Journal of Pharmacognosy and Phytochemistry, 2019)Background: Tuberculosis (TB) caused by Mycobacterium tuberculosis remains an important public health issue worldwide and TB patients are reported to use conventional drugs concurrently with medicinal plants. This study ... -
In-vitro antihelminthic activity of alcoholic extract from Paullinia pinnata Linn against Ascaris suum
(Revista Cubana de Plantas Medicinales, 2018)Introduction: Medicinal plants are used both for the treatment of certain conditions and to preserve health and vitality. According to estimates by the World Health Organization, 80% of the world population, excluding ... -
Inappropriate usage of selected antimicrobials: Comparative residue proportions in rural and urban beef in Uganda
(PloS one, 2019)Introduction In most developing countries like Uganda, antimicrobials including β-lactams and tetracyclines are used indiscriminately in livestock. When livestock get sick and treatment is necessary, some producers and ... -
Infections
(African Health Sciences, 2011-09)Background: Medicinal plants in Uganda and other developing countries have been scientifically demonstrated to have medicinal benefits but few or none have been translated to products for clinical use. Most herbal products ... -
Influence of hormonal status on behavioral responses to an acute ethanol challenge during ethanol withdrawal in male and female rats
(Pharmacology, Biochemistry and Behavior, 2008)We previously reported significant sex differences in ethanol withdrawal (EW) recovery as well as in sensitivity to GABAA receptor modulators during EW. The aim of the present study was to determine if hormonal status ... -
An investigation into the number and nature of the urgent care consultations managed and referred by community pharmacists in South-East England
(Primary Health Care Research & Development, 2020)Background: Community pharmacies are recognised as an under-utilised, accessible resource that could support the urgent care agenda. This study aimed to provide a snapshot of the number and nature of urgent care requests ... -
Laboratory and simulated semi-field larvicidal efficacy of Aframomum angustifolium (Sonn.) K. Schum and Tagetes patula essential oils against Anopheles gambiae
(Journal of Natural Pesticide Research, 2024)Introduction: Malaria is a vector-borne, important public health problem spread by mosquitoes in tropical regions. The use of synthetic insecticides for mosquito control has been linked to insecticide resistance and ... -
Ligand-protein interactions of plant-isolated (9z,12z)-octadeca-9,12-dienoic acid with B-ketoacyl-Acp synthase (KasA) in potential anti-tubercular drug designing
(Scientific African, 2021)Mycobacterium tuberculosis remains one of the world’s contributors to mortality. With the emergence of SARS-CoV-2 coinfections, patients with TB are predisposed to being more heavily weighed down by COVID-19 disease and ... -
Ligand-protein interactions of plant-isolated (9z,12z)-octadeca-9,12-dienoic acid with B-ketoacyl-Acp synthase (KasA) in potential anti-tubercular drug designing
(Scientific African, 2020)Mycobacterium tuberculosis remains one of the world’s contributors to mortality. With the emergence of SARS-CoV-2 coinfections, patients with TB are predisposed to being more heavily weighed down by COVID-19 disease and ... -
The meaning of caring for patients with cancer among traditional medicine practitioners in Uganda: A grounded theory approach
(PLOS Global Public Health, 2023)Traditional medicine practitioners (TMPs) are a critical part of healthcare systems in many sub-Saharan African countries and play vital roles in caring for patients with cancer. Despite some progress in describing TMPs’ ... -
Microbial and physical evaluation of selected cough syrups sold at peripheral drug outlets in Bushenyi District, South Western Uganda
(African Journal of Pharmacy and Pharmacology, 2023)Syrups, being non-sterile liquid pharmaceutical formulations, are prone to microbial contamination. The most common microbial contaminants are bacteria and fungi. Contamination of oral liquid pharmaceuticals makes them ... -
Mitigating the burden of adverse drug reactions in older inpatients: short commentary
(Aging Communications, 2022)Studies have consistently identified older age as a predictor of adverse drug reaction (ADR) and the related adverse. The safety data collected during the premarketing phase is lacking due to the omission of distinctive ... -
New Putative Antimicrobial Candidates: In silico Design of Fish-Derived Antibacterial Peptide-Motifs
(Frontiers in Bioengineering and Biotechnology, 2020)Antimicrobial resistance remains a great threat to global health. In response to the World Health Organizations’ global call for action, nature has been explored for novel and safe antimicrobial candidates. To date, fish ... -
Off‑label antibiotic use among paediatric in‑patients: a mixed‑method prospective study at a tertiary hospital in southwestern Uganda
(International Journal of Clinical Pharmacy, 2020)Background: The off-label use of drugs to treat children is a global practice attributed to the traditional exclusion of children from clinical trials mainly due to practical and ethical reasons. Off-label drug use carries ... -
Overview of processed excipients in ocular drug delivery: Opportunities so far and bottlenecks
(Heliyon, 2023-12-23)Ocular drug delivery presents a unique set of challenges owing to the complex anatomy and physiology of the eye. Processed excipients have emerged as crucial components in overcoming these challenges and improving the ...