Browsing Research Article by Title
Now showing items 21-40 of 123
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Concomitant herbal medicine and Antiretroviral Therapy (ART) use among HIV patients in Western Uganda: A cross-sectional analysis of magnitude and patterns of use, associated factors and impact on ART adherence
(AIDS Care, 2012)Use of herbal medicines among patients receiving Anti-Retroviral Therapy (ART) remains by far an un characterised phenomenon in Africa and Uganda specifically. We evaluated the use of herbal medicines among patients on ART ... -
Confronting the complexities of antimicrobial management for Staphyloccous aureus causing bovine mastitis: an innovative paradigm
(Irish Veterinary Journal, 2024)Globally, Mastitis is a disease commonly affecting dairy cattle which leads to the use of antimicrobials. The majority of mastitis etiological agents are bacterial pathogens and Staphylococcus aureus is the predominant ... -
Correction: Potential Cost-Effectiveness of Prenatal Distribution of Misoprostol for Prevention of Postpartum Hemorrhage in Uganda
(PLOS ONE, 2016-03-21)The correct sentences are “In the base-case analysis, misoprostol distribution lowered the expected incidence of PPH by 1.2% (95% credibility interval (CrI): 0.55%, 1.95%), mortality by 0.08% (95% CrI: 0.04%, 0.13%) and ... -
COVID-19 vaccine hesitancy: assessing the prevalence, predictors, and effectiveness of a community pharmacy based counseling interventio
(BMC Public Health, 2024)Background: Coronavirus disease (COVID-19) vaccine hesitancy is a global challenge. In low- and middle-income countries (LMICs), the problem has persisted despite vaccine availability and decreasing infections. In Uganda, ... -
D-optimal mixture design optimized solid formulation containing fruits extracts of Momordica charantia and Abelmoschus esculentus
(PLoS ONE, 2022-06-24)Fruit extracts of Momordica charantia L. (Cucurbitaceae) and Abelmoschus esculentus (L.) Moench (Malvaceae) have shown promising antidiabetic activities in clinical trials. However, they remain underutilized due to ... -
Determination of the abortifacient activity of the aqueous extract of Phytolacca dodecandra (L’Her) leaf in Wistar rats
(African Journal of Pharmacy and Pharmacology, 2015)Throughout history women have tried to control their fertility using herbal remedies; traditionally Phytolacca dodecandra leaves have been used as an abortifacient. The objective of this study was to determine the ... -
Development and Validation of ‘Prediction of Adverse Drug Reactions in Older Inpatients (PADROI)’ Risk Assessment Tool
(Clinical Interventions in Aging, 2022)Background: Adverse drug reactions (ADR) detection and prediction methods in hospitalized older adults remain imprecise. The identification of the risk factors for ADRs in this group of patients is crucial to develop ... -
Dietary Content and Potential Health Risks of Metals in Commercial Black Tea in Kampala (Uganda)
(Journal of Food Research, 2017)Tea (Camellia sinensis (L.) Kuntze) is among the most widely consumed non-alcoholic beverages. It is a rich source of essential dietary elements mainly potassium and manganese. Tea may also contain toxic metals such as ... -
Differences in Symptom Severity and Quality of Life among Patients with Cancer Using Conventional Therapies with/ without Herbal Medicines in Uganda: A Cross-Sectional Study
(Asian Pacific Journal of Cancer Prevention, 2023)Objective: Patients with cancer experience numerous symptoms related to cancer and treatment side effects that reduce their quality of life (QOL). Although herbal medicine (HM) is used to manage such symptoms by patients ... -
Dioscorea bulbifera, a highly threatened African medicinal plant, a review
(Cogent Biology, 2019-06)Dioscorea bulbifera bulbils are used in the treatment of Piles, dysentery, syphilis, ulcers, cough, leprosy, diabetes, asthma, and cancer. It is a raw material for contraceptives, and it is one of the most consumed yam ... -
Documentation and Phytochemical Screening of Most Commonly used Nutri-Medicinal Plants by Pregnant Women in Kyeizooba, Bushenyi District, Western Uganda
(Journal of Pharmacognosy & Natural Products, 2020-01)Nutri-medicinal plants are widely used as a remedy for some ailments among pregnant women worldwide. There are different medicinal plants used by pregnant women in Uganda depending on the culture and knowledge of these ... -
Dried-leaf Artemisia annua: A practical malaria therapeutic for developing countries?
(World journal of pharmacology,, 2014)Artemisinin from the plant Artemisia annua (A. annua) L., and used as artemisinin combination therapy (ACT), is the current best therapeutic for treating malaria, a disease that hits children and adults especially in ... -
Dried-leaf Artemisia annua: A practical malaria therapeutic for developing countries?
(World journal of pharmacology, 2014-12)Artemisinin from the plant Artemisia annua (A. annua) L, and used as artemisinin combination therapy (ACT), is the current best therapeutic for treating malaria, a disease that hits children and adults especially in ... -
Drug-like properties of anticancer molecules elucidated from Eichhornia crassipes
(Journal of Pharmacognosy and Phytochemistry, 2018)Eichhornia crassipes is reported to have molecules that are active against liver, cervical, breast cancers and melanoma cells. This systematic review was conducted according to Cochrane hand book of systematic review and ... -
Drug-related problems and associated factors among patients with kidney dysfunction at a tertiary hospital in southwestern Uganda: a prospective observational study
(BMC nephrology, 2023)Background: Kidney dysfunction is a common, progressive condition that is increasingly becoming a global public health issue. Because the kidneys are the major route for drug excretion, impaired renal function can change ... -
Effect of Ethanol Leaf Extract of Khat (Catha edulis forsk) on Prefrontal Cortex Oxidative Markers and Hematological Profile of Wistar Rats
(Journal of Scientific Research & Reports, 2021)Aim: This study evaluated the effect of ethanol leaf extract of Catha edulis on the prefrontal cortex oxidative markers and hematological profile of Wistar rats. Study Design: The study design was experimental. Place ... -
Effect of high-dose rifampicin on efavirenz pharmacokinetics: drug–drug interaction randomized trial
(Journal of Antimicrobial Chemotherapy, 2020-01)Background: High-dose rifampicin is considered to shorten anti-TB treatment duration but its effect on antiretroviral metabolism is unknown. Objectives: To assess the effect of doubling the rifampicin dose (to 20 mg/kg/day, ... -
Effects of aqueous root bark extract of Citropsis articulata (Swingle & Kellerman) on sexual function in male rats
(Academic Journals, 2014-11-11)About 80% of the world’s population uses herbal medicine for the treatment of various health conditions. Erectile dysfunction is one of the conditions commonly treated using traditional herbs on large scale. In this ... -
Effects of Commercial Boifertilizers on Growth and Yield of Antimalarial Compounds of Artemi sia Annua
(International Journal of Plant & Soil Science, 2023)Introduction: Artemisia annua is a medicinal plant grown by Ugandan farmers in Kabale and Kabarole. It is particularly used in preparation of antimalarial herbal teas used to control and prevent malaria. The content of ... -
Effects of Physalis peruviana L. (leaf crude extracts) on blood glucose and functional biomarkers in streptozotocin-nicotinamide-induced diabetic rats
(Die Pharmazie-An International Journal of Pharmaceutical Sciences, 2024)Promoting antidiabetic phytomedicines necessitates evidence-based preclinical investigations, particularly in animal models. The present study investigated the validity of using the streptozotocin-nicotinamide-induced type ...