Browsing Research Article by Issue Date
Now showing items 21-40 of 98
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Less Noise, More Hacking: How to Deploy Principles from MIT’s Hacking Medicine to Accelerate Health Care
(International Journal of Technology Assessment in Health Care, 2014)Medical technology offers enormous potential for scalable medicine to improve the quality and access in health care while simultaneously reducing cost. However, current medical device innovation within companies often only ... -
Caregiver Perceptions and Motivation for Disclosing or Concealing the Diagnosis of HIV Infection to Children Receiving HIV Care in Mbarara, Uganda: A Qualitative Study
(2014-03-25)Background: Disclosure of the diagnosis of HIV to HIV-infected children is challenging for caregivers. Despite current recommendations, data suggest that levels of disclosure of HIV status to HIV-infected children receiving ... -
The development and implementation of a theory-informed, integrated mother-child intervention in rural Uganda
(Social Science & Medicine, 2015)Rationale: A randomised cluster effectiveness trial of a parenting intervention in rural Uganda found benefits to child development among children 12e36 months, relevant parenting practices related to stimulation, hygiene ... -
Understanding the role of age in HIV disclosure rates and patterns for HIV-infected children in southwestern Uganda
(AIDS care, 2015)Highly active antiretroviral therapy has enabled HIV-infected children to survive into adolescence and adulthood, creating need for their own HIV diagnosis disclosure. Disclosure has numerous social and medical benefits ... -
Reasons for non-timely completion of the routine infant immunization schedule by children in rural South West Uganda
(Canadian Journal of Public Health, 2015)Many Ugandan children still die of vaccine-preventable diseases like pneumococcal pneumonia, rotavirus diarrhea and measles.1 Fewer children in low-income countries like Uganda complete their routine infant immunization ... -
Post-discharge mortality prediction in under 5s with acute infectious diseases: a prospective cohort study
(The Lancet Global Health, 2015)Background: Acute infectious diseases are an important contributor to under-5 mortalities. Mortality following discharge is an important but poorly recognised contributor to overall mortality. The identification of at-risk ... -
Explaining Antiretroviral Therapy Adherence Success Among HIV-Infected Children in Rural Uganda: A Qualitative Study
(AIDS and Behavior, 2015)High adherence is critical for achieving clinical benefits of HIV antiretroviral therapy (ART) and particularly challenging for children. We conducted 35 qualitative interviews with caregivers of HIV-infected Ugandan ... -
Know Your Audience: Predictors of Success for a Patient-Centered Texting App to Augment Linkage to HIV Care in Rural Uganda
(Journal of medical Internet research, 2015)Background: Despite investments in infrastructure and evidence for high acceptability, few mHealth interventions have been implemented in sub-Saharan Africa. Objective: We sought to (1) identify predictors of uptake of ... -
Assessment of HIV antiretroviral therapy adherence by measuring drug concentrations in hair among children in rural Uganda
(AIDS Care, 2015)Current tools for measuring medication adherence have significant limitations, especially among pediatric populations. We conducted a prospective observational study to assess the use of antiretroviral (ARV) drug levels ... -
Effects of a parenting intervention to address maternal psychological wellbeing and child development and growth in rural Uganda: a community-based, cluster-randomised trial
(The Lancet Global Health, 2015-07-03)Background: Parenting interventions have been implemented to improve the compromised developmental potential among 39% of children younger than 5 years living in low-income and middle-income countries. Maternal wellbeing ... -
Inhaled Nitric Oxide as an Adjunctive Treatment for Cerebral Malaria in Children: A Phase II Randomized Open-Label Clinical Trial
(Published by Oxford University Press on behalf of the Infectious Diseases Societyof America., 2015-07-22)Background. Children with cerebral malaria (CM) have high rates of mortality and neurologic sequelae. Nitric oxide (NO) metabolite levels in plasma and urine are reduced in CM. Methods. This randomized trial assessed the ... -
Prevalence and Predictors of Functional Vitamin K Insufficiency in Mothers and Newborns in Uganda
(Nutrients, 2015-10-16)Vitamin K deficiency bleeding (VKDB) in infancy is a serious but preventable cause of mortality or permanent disability. Lack of epidemiologic data for VKDB in sub-Saharan Africa hinders development and implementation of ... -
Prospective study of the mental health consequences of sexual violence among women living with HIV in rural Uganda
(Journal of interpersonal violence, 2016)The association between sexual violence and depression is well known, but the temporal aspects of the association have not been well established. We analyzed data from a cohort of 173 HIV-positive women in rural Uganda who ... -
Detection Yield and Tolerability of String Test for Diagnosis of Childhood Intrathoracic Tuberculosis
(The Pediatric infectious disease journal, 2016)Background: Difficulty to obtain sputum in children complicates diagnosis of intrathoracic tuberculosis (TB). The intragastric string test (ST) used for retrieval of enteric pathogens might be an alternative specimen ... -
The PAediatric Risk Assessment (PARA) Mobile App to Reduce Postdischarge Child Mortality: Design, Usability, and Feasibility for Health Care Workers in Uganda
(JMIR mHealth and uHealth, 2016)Background: Postdischarge death in children is increasingly being recognized as a major contributor to overall child mortality. The PAediatric Risk Assessment (PARA) app is an mHealth tool developed to aid health care ... -
Pediatric out-of-hospital deaths following hospital discharge
(African Health Sciences, 2016)Background: Out-of-hospital death among children living in resource poor settings occurs frequently. Little is known about the location and circumstances of child death following a hospital discharge. Objectives: This ... -
Selecting candidate predictor variables for the modelling of post-discharge mortality from sepsis: a protocol development project
(African health sciences, 2016)Background: Post-discharge mortality is a frequent but poorly recognized contributor to child mortality in resource limited countries. The identification of children at high risk for post-discharge mortality is a critically ... -
Scheduled Follow-Up Referrals and Simple Prevention Kits Including Counseling to Improve Post-Discharge Outcomes Among Children in Uganda: A Proof-of-Concept Study
(Global Health: Science and Practice, 2016)Background: Recurrent illness following hospital discharge is a major contributor to childhood mortality in resource poor countries. Yet post-discharge care is largely ignored by health care workers and policy makers due ... -
Maternal Attitudes about Objectively Monitored Bednet Use in Rural Uganda
(Malaria Research and Treatment, 2016)Insecticide-treated bednets (ITNs) are a mainstay of malaria prevention, yet poor adherence poses a major barrier to effective prevention. Self-reports of bednet use suffer from recall and social desirability biases. We ... -
Pediatric in-Hospital Death from Infectious Disease in Uganda: Derivation of Clinical Prediction Models
(PLoS ONE, 2016-03-10)Background: Pediatric hospital mortality from infectious diseases in resource constrained countries remains unacceptably high. Improved methods of risk-stratification can assist in referral decision making and resource ...