Department of Internal Medicine: Recent submissions
Now showing items 241-258 of 258
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Timing of Antiretroviral Therapy after Diagnosis of Cryptococcal Meningitis
(2014-06-26)Background Cryptococcal meningitis accounts for 20 to 25% of acquired immunodeficiency syndrome–related deaths in Africa. Antiretroviral therapy (ART) is essential for survival; however, the question of when ART should ... -
Community perceptions about dementia in southwestern Uganda
(BMC Geriatrics, 2020)Background: With the increasing number of people surviving into older age in Africa, dementia is becoming a public health concern. Understanding the social dynamics of dementia in resource-limited settings is critical ... -
Incidence and predictors of early loss to follow up among patients initiated on protease inhibitor-based second-line antiretroviral therapy in southwestern Uganda
(AIDS Research and Therapy, 2021-03-20)Abstract Background: Good adherence to antiretroviral therapy (ART) and retention in care are essential for the efectiveness of an HIV care program. With the current increase in numbers of people living with HIV taking ... -
Head and Neck Squamous Cell Carcinoma in Western Uganda: Disease of Uncertainty and Poor Prognosis
(Sage, 2018)Objectives Patients with head and neck squamous cell carcinoma (HNSCC) have symptoms that masquerade as benign conditions, resulting in late presentations. The objective is to describe characteristics and stages of patients ... -
Post-traumatic stress disorder, psychiatric comorbidities and associated factors among refugees in Nakivale camp in southwestern Uganda
(Springer Nature, 2020)Background: Armed conflict in Africa has led to displacement of over 24.2 million people, more than 1.4 million of whom are living in Uganda. Studies show that refugees living in Ugandan refugee settlements are at increased ... -
Prevalence, correlates for early neurological disorders and association with functioning among children and adolescents with HIV/ AIDS in Uganda
(Springer Nature, 2019)Background: The aim of this study was to determine the prevalence of neurological disorders and their associated correlates and relations with clinical and behavioural problems among children and adolescents with HIV/AIDS ... -
Perceived stigma and associated factors among children and adolescents with epilepsy in south western Uganda
(Elsevier, 2018)Purpose: To determine the prevalence of perceived stigma and its associated factors among children and adolescents with epilepsy in southwestern Uganda. Methods: We conducted a cross sectional study at a large referral ... -
Development and validation of a 20-item screening scale to detect major depressive disorder among adolescents with HIV in rural Uganda
(Elsevier Ltd, 2018)Background: Depression is a major cause of disability among children and adolescents and is associated with elevated risks for substance abuse, HIV transmission risk behavior, and suicide. Among adolescents living with HIV ... -
Prevalence and correlates for ADHD and relation with social and academic functioning among children and adolescents with HIV/AIDS in Uganda
(Springer Nature, 2017)Background: Aim of this study was to determine the prevalence of attention-deficit/hyperactivity disorder (ADHD), its associated correlates and relations with clinical and behavioural problems among children and adolescents ... -
Knowledge of integrated management of childhood illnesses community and family practices (C-IMCI) and association with child undernutrition in Northern Uganda
(Bio Med Central public health, 2014)Background: Childhood undernutrition is a major challenge in Uganda with a prevalence of wasting and stunting at 5% and 33%, respectively. Community and family practices of the Integrated Management of Childhood ... -
Prevalence and factors associated with depression symptoms among school‑going adolescents in Central Uganda
(Bio Med Central, 2016)Background: Depression in adolescents constitutes a global public health concern. However, data on its prevalence and associated factors are limited in low income countries like Uganda. Methods: Using a cross-sectional ... -
Valued experiences of graduate students in their role as educators in undergraduate training in Ugandan medical schools
(Springer Nature, 2017)Background: In most medical schools, graduate students, sometimes referred to as graduate teaching assistants, often participate in the training of undergraduate students. In developing countries like Uganda, are ... -
The Kynurenine Pathway of Tryptophan Catabolism, CD4+ T-Cell Recovery, and Mortality Among HIV-Infected Ugandans Initiating Antiretroviral Therapy
(Oxford University Press, 2014)Background. Human immunodeficiency virus (HIV) infection–induced indoleamine 2,3-dioxygenase-1 (IDO) expression in activated monocytes and dendritic cells catabolizes tryptophan to kynurenine and other downstream catabolites ... -
The Dynamic Relationship Between Social Support and HIV-Related Stigma in Rural Uganda
(Springer, 2014)Abstract Background Cross-sectional studies show that human immunodeficiency virus (HIV) stigma is negatively correlated with social support. Purpose The purpose of this study is to examine the bidirectional relationship ... -
Point-of-Care Diagnosis and Prognostication of Cryptococcal Meningitis With the Cryptococcal Antigen Lateral Flow Assay on Cerebrospinal Fluid
(Oxford University Press, 2013)The cryptococcal antigen (CRAG) lateral flow assay (LFA) had 100% sensitivity and specificity on cerebrospinal fluid samples. Pretreatment LFA titers correlated with quantitative cultures (R2 = 0.7) and predicted 2- and ... -
The Effect of Therapeutic Lumbar Punctures on Acute Mortality From Cryptococcal Meningitis
(2014)Introduction. Cryptococcal meningitis is the most common cause of adult meningitis in sub-Saharan Africa. Raised intracranial pressure (ICP) is common in cryptococcosis. Prior studies suggest elevated ICP is associated with ... -
Determinants of Mortality in a Combined Cohort of 501 Patients With HIV-Associated Cryptococcal Meningitis
(Oxford University Press, 2013)Background. Cryptococcal meningitis (CM) is a leading cause of death in individuals infected with human immunodeficiency virus (HIV). Identifying factors associated with mortality informs strategies to improve outcomes. Methods. ... -
Science-based health innovation in Rwanda:unlocking the potential of a late bloomer
(BMC, 2010-12-13)This paper describes and analyses Rwanda’s science-based health product‘innovation system’,highlighting examples of indigenous innovation and good practice. We use an innovation systems framework,which takes into account ...
