Research Articles: Recent submissions
Now showing items 361-380 of 440
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Effectiveness of nevirapine and zidovudine in a pilot program for the prevention of mother-to-child transmission of HIV-1 in Uganda
(African Health Sciences, 2004-12)Background: Single dose nevirapine and a short course of zidovudine (AZT) are now administered in most hospitals in Uganda to prevent mother-to-child transmission (MTCT) of HIV. The effectiveness of these antiretroviral ... -
Disinhibition in Risky Sexual Behavior in Men, but Not Women, during Four Years of Antiretroviral Therapy in Rural, Southwestern Uganda
(PLoS ONE, 2013-07-19)Background: In resource-rich areas, risky sexual behavior (RSB) largely diminishes after initiation of anti-retroviral therapy, with notable exceptions among some populations who perceive a protected benefit from anti-retroviral ... -
Comprehension and construct validity of the Visual Prostate Symptom Score (VPSS) by men with obstructive lower urinary tract symptoms in rural Africa
(Canadian Urological Association Journal, 2017-11-01)Introduction: The Visual Prostate Symptom Score (VPSS) is an image-based interpretation of the International Prostate Symptom Score (IPSS) intended to quantify frequency, nocturia, weak stream, and quality of life (QoL) ... -
Oral health status of school children in Mbarara, Uganda
(African health sciences, 2007)Background: Despite the need for oral health morbidity surveys to aid in reviewing of the oral health services, dental data of Ugandan children is scanty. Objectives: to describe the magnitude and distribution of selected ... -
Immunogenicity of Fractional Doses of Tetravalent A/C/Y/W135 Meningococcal Polysaccharide Vaccine: Results from a Randomized Non-Inferiority Controlled Trial in Uganda
(PLoS Negl Trop Dis, 2008)Background: Neisseria meningitidis serogroup A is the main causative pathogen of meningitis epidemics in sub-Saharan Africa. In recent years, serogroup W135 has also been the cause of epidemics. Mass vaccination campaigns ... -
Harnessing the Power of Light to Treat Staphylococcal Infections Focusing on MRSA
(Current pharmaceutical design, 2015)Methicillin-resistant Staphylococcus aureus (MRSA) has become the most important drug-resistant microbial pathogen in countries throughout the world. Morbidity and mortality due to MRSA infections continue to increase ... -
Comparison of Self-Reported Alcohol Consumption to Phosphatidylethanol Measurement among HIV-Infected Patients Initiating Antiretroviral Treatment in Southwestern Uganda
(PLoS ONE, 2014-12-01)Background: Alcohol consumption among HIV-infected patients may accelerate HIV disease progression or reduce antiretroviral therapy adherence. Self-reported alcohol use is frequently under-reported due to social desirability ... -
Effect of Village Health Team Home Visits and Mobile Phone Consultations on Maternal and Newborn Care Practices in Masindi and Kiryandongo, Uganda: A Community- Intervention Trial
(PLOS ONE, 2016)Introduction The World Health Organisation recommends home visits conducted by Community Health Workers (in Uganda known as Village Health Teams—VHTs) in order to improve maternal and newborn health. This study measured ... -
Comparative feasibility of implementing rapid diagnostic test and microscopy for parasitological diagnosis of malaria in Uganda
(Malaria Journal, 2011)Background: In Uganda, parasite-based diagnosis is recommended for every patient suspected to have malaria before prescribing anti-malarials. However, the majority of patients are still treated presumptively especially in ... -
Characterizing the Flow of Health Information in Rural Uganda: Is there a Role for Mobile Phones?
(Journal of Public Health in Developing Countries, 2015-07-01)Background: The United Nations’ post-2015 development agenda stresses need for a “data revolution.” In Uganda, capturing recent health data can be challenging. Capitalizing on the expansion of mobile phone access in ... -
Seroprevalence of Ebola virus infection in Bombali District, Sierra Leone
(Journal of public health in Africa, 2017)A serosurvey of anti-Ebola Zaire virus nucleoprotein IgG prevalence was carried out among Ebola virus disease survivors and their Community Contacts in Bombali District, Sierra Leone. Our data suggest that the specie of ... -
Pharyngeal carriage of Neisseria meningitidis in 2—19-year-old individuals in Uganda
(Transactions of the Royal Society of Tropical Medicine and Hygiene, 2006)In southern Uganda, only sporadic cases of serogroup A meningococcal disease have been reported since 2000. As part of an immunogenicity study of the tetravalent meningococcal polysaccharide vaccine, nasopharyngeal swab ... -
Burden of depressive symptoms and non-alcohol substance abuse; and their association with alcohol use and partner violence: a cross-sectional study in four sub-Saharan Africa countries
(Global Mental Health, 2018-10)In sub-Saharan Africa, there are limited data on burden of non-alcohol substance abuse (NAS) and depressive symptoms (DS), yet potential risk factors such as alcohol and intimate partner violence (IPV) are common and NAS ... -
Brain drain in sub-Saharan Africa: contributing factors, potential remedies and the role of academic medical centres
(Archives of Disease in Childhood, 2012-09-08)A double jeopardy exists in resource-limited settings (RLS) in sub-Saharan Africa (SSA): there are a disproportionately greater number of acutely ill patients, but a paucity of healthcare workers (HCW) to care for them. ... -
Birth plans and health facility based delivery in Rural Uganda
(East African Medical Journal, 2006-03-03)Objectives: To evaluate whether the completion of birth plans is associated with delivery in a health facility and the perceptual causes of birth plan completion and health facility based delivery were explored according ... -
Beyond HIV-serodiscordance: Partnership communication dynamics that affect engagement in safer conception care
(PLoS ONE, 2017-09-07)Introduction We explored acceptability and feasibility of safer conception methods among HIV-affected couples in Uganda. Methods We recruited HIV-positive men and women on antiretroviral therapy (ART) (`index') from ... -
Assessment of three new parasite lactate dehydrogenase (pan-pLDH) tests for diagnosis of uncomplicated malaria
(Transactions of the Royal Society of Tropical Medicine and Hygiene, 2008)A study to assess the diagnostic capabilities of three parasite lactate dehydrogenase (pan-pLDH) tests, Vistapan®, CarestartTM and Parabank®, was conducted in Uganda. An HRP2 test, Paracheck-Pf®, and a Giemsa-stained blood ... -
Are rapid diagnostic tests more accurate in diagnosis of plasmodium falciparum malaria compared to microscopy at rural health centres?
(Malaria Journal, 2010)Background: Prompt, accurate diagnosis and treatment with artemisinin combination therapy remains vital to current malaria control. Blood film microscopy the current standard test for diagnosis of malaria has several ... -
Barriers to the implementation of programs for the prevention of mother-to-child transmission of HIV: A cross-sectional survey in rural and urban Uganda
(AIDS Research and Therapy, 2005-10-28)Background: Implementation of programs for the prevention of mother-to-child transmission (PMTCT) of HIV faces a variety of barriers and challenges. The assessment of these challenges has generally been conducted in large ... -
Associations between the severity of obstructive lower urinary tract symptoms and care-seeking behavior in rural Africa: A crosssectional survey from Uganda
(PLoS ONE, 2017-03-16)Study type A cross sectional survey. Background Global estimates indicate that by 2018 2.3 billion individuals worldwide will suffer from lower urinary tract symptoms (LUTS), with 1.1 billion having LUTS related to ...