Department of Microbiology: Recent submissions
Now showing items 61-80 of 103
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Prevalence and correlates of carotid plaque in a mixed HIV-serostatus cohort in Uganda
(Springer Nature, 2021-12-07)Background: The extent to which the risk of atherosclerotic cardiovascular disease (ACVD) is increased among people living with HIV (PLWH) in sub-Saharan Africa remains unknown. Setting: Cross-sectional analysis nested ... -
Prevalence and antimicrobial susceptibility patterns of Neisseria gonorrhea among the symptomatic patients attending outpatient department in Lyatonde district hospital southwestern Uganda
(International Journal of Scientific Reports, 2019-02)Background: Neisseria gonorrhea is one of the neglected diseases of public health importance causing symptomatic, suppurative discharge in males and being asymptomatic in females. This cross-sectional study was aimed at ... -
Prevalence and antibiotic susceptibility patterns of clinical isolates of methicillin- resistant staphylococcus aureus in a tertiary care hospital in western Uganda
(British Microbiology Research Journal, 2014-06-30)Aim: To determine the prevalence and antibiotic susceptibility patterns of clinical isolates of methicillin resistant Staphylococcus aureus isolated at Mbarara Regional Referral Hospital. Method: A total of 400 S. aureus ... -
Antimicrobial Resistance Patterns and Molecular Characterization of Klebsiella pneumoniae in Clinical Isolates at Mbarara Regional Referral Hospital
(Advances in Infectious Diseases, 2019-08)Background: Klebsiella pneumoniae is one of the most frequent opportunistic pathogens causing a range of infections and being resistant for beta- lactamases (ESBL) and Carbapenemases. Aim: The aim of the present study ... -
Rifampicin and isoniazid drug resistance among patients diagnosed with pulmonary tuberculosis in southwestern Uganda
(PloS one, 2021)Multidrug-resistant tuberculosis (MDR-TB) has become a major threat to the control of tuberculosis globally. Uganda is among the countries with a relatively high prevalence of tuberculosis despite significant control ... -
Phylogenetic analysis of multidrug resistant E. coli isolates from the urinary tract in Bushenyi district, Uganda using the new Clermont phylotyping method
(African Journal of Microbiology Research, 2020)Due to the increasing rates of multidrug resistance (MDR) among the Enterobacteriaceae that cause urinary tractinfections (UTIs), selection of antimicrobial agents for empirical therapy is becoming a major challenge. This ... -
Status of pulmonary fungal infections among individuals with clinical signs of pulmonary tuberculosis at a University Teaching Hospital in Southwestern Uganda
(Research square, 2021)Background: Pulmonary mycoses are very important diseases of the respiratory tract and are responsible for significant morbidity and mortality rates worldwide. However, less attention has been paid to them. In this study ... -
Status of pulmonary fungal pathogens among individuals with clinical features of pulmonary tuberculosis at Mbarara University Teaching Hospital in Southwestern Uganda
(Therapeutic advances in infectious disease, 2021)Background: Pulmonary mycoses are important diseases of the respiratory tract caused by pulmonary fungal pathogens. These pathogens are responsible for significant morbidity and mortality rates worldwide; however, less ... -
Mycobacterium tuberculosis spoligotypes and drug susceptibility pattern of isolates from tuberculosis patients in South-Western Uganda
(BMC Infectious Diseases, 2011-03-31)Background: Determination of the prevalence and drug susceptibility of the M. tuberculosis strains is important in tuberculosis control. We determined the genetic diversity and susceptibility profiles of mycobacteria ... -
Multidrug resistance among Escherichia coli and Klebsiella pneumoniae carried in the gut of out-patients from pastoralist communities of Kasese district, Uganda
(PLoS ONE, 2018-07-17)Introduction: Antimicrobial resistance is a worldwide public health emergency that requires urgent attention. Most of the effort to prevent this coming catastrophe is occurring in high income countries and we do not know ... -
Molecular Characterization of Salmonella from Human and Animal Origins in Uganda
(International Journal of Bacteriology, 2017-05-28)Sporadic Salmonella outbreaks with varying clinical presentations have been on the rise in various parts of Uganda. The sources of outbreaks and factors underlying the different clinical manifestation are curtailed by ... -
Methicillin-Resistant Staphylococcus aureus Nasal Colonization among Healthcare Workers at Kampala International University Teaching Hospital, Southwestern Uganda
(Canadian Journal of Infectious Diseases and Medical Microbiology, 2019-03-10)Whereas Staphylococcus aureus is a pathogen, it colonizes healthy people as normal flora without causing any symptoms or illness. Probably because of greater exposure, healthcare workers (HCWs) are more colonized, serving ... -
Low Resistance to First and Second Line Anti- Tuberculosis Drugs among Treatment Naive Pulmonary Tuberculosis Patients in Southwestern Uganda
(PLoS ONE, 2015-02-06)Background: There are limited data on region-specific drug susceptibility of tuberculosis (TB) in Uganda. We performed resistance testing on specimens collected from treatment-naive patients with to provide data to guide ... -
Malaria is an uncommon cause of adult sepsis in south-western Uganda
(Malaria Journal, 2013-05-01)Background: Malaria is often considered a cause of adult sepsis in malaria endemic areas. However, diagnostic limitations can make distinction between malaria and other infections challenging. Therefore, the objective of ... -
Isolation and Antibiotic Susceptibility Testing of Haemophilus influenzae from Nasopharynx of Children under Five Years Attending Maternal and Child Health Clinic in Mbarara Regional Referral Hospital
(Canadian Journal of Infectious Diseases and Medical Microbiology, 2019-03-03)Background: H. influenzae remains an organism of a major public health challenge worldwide despite the availability of the Hib vaccine, particularly among children under 5 years. Information on the current carriage status ... -
Prevalence of Methicillin Resistant Staphylococcus aureus among Isolates from Wounds in Surgical Wards at Kabale Regional Referral Hospital, South Western Uganda
(British Microbiology Research Journal, 2016)Background: Methicillin resistant S. aureus (MRSA) is a multidrug resistant organism that threatens the continued effectiveness of antibiotics worldwide and causes a threat almost exclusively in hospitals and long-term ... -
Implementation of the World Health Organization Global Antimicrobial Resistance Surveillance System in Uganda, 2015-2020: Mixed-Methods Study Using National Surveillance Data
(JMIR public health and surveillance, 2021)Background: Antimicrobial resistance (AMR) is an emerging public health crisis in Uganda. The World Health Organization (WHO) Global Action Plan recommends that countries should develop and implement National Action Plans ... -
Whole genome sequences of multi-drug resistant Escherichia coli isolated in a Pastoralist Community of Western Uganda: Phylogenomic changes, virulence and resistant genes
(PLoS ONE, 2020-05-29)Background: The crisis of antimicrobial resistance is already here with us, affecting both humans and animals alike and very soon, small cuts and surgeries will become life threatening. This study aimed at determine the ... -
Detection of Plasmodium Species by High-Resolution Melt Analysis of DNA from Blood Smears Acquired in Southwestern Uganda
(Journal of Clinical Microbiology, 2017-10-02)Microscopic diagnosis of malaria using Giemsa-stained blood smears is the standard of care in resource-limited settings. These smears represent a potential source of DNA for PCR testing to confirm Plasmodium infections or ...
