dc.contributor.author | Namagga, Jane Kasozi | |
dc.contributor.author | Rukundo, Godfrey Zari | |
dc.contributor.author | Niyonzima, Vallence | |
dc.contributor.author | Voss, Joachim | |
dc.date.accessioned | 2022-02-01T13:48:00Z | |
dc.date.available | 2022-02-01T13:48:00Z | |
dc.date.issued | 2021-07 | |
dc.identifier.citation | Namagga, J. K., Rukundo, G. Z., Niyonzima, V., & Voss, J. (2021). Depression and HIV associated neurocognitive disorders among HIV infected adults in rural southwestern Uganda: a cross-sectional quantitative study. BMC psychiatry, 21(1), 1-8. | en_US |
dc.identifier.uri | http://ir.must.ac.ug/xmlui/handle/123456789/1339 | |
dc.description.abstract | Background: HIV-Associated Neurocognitive Disorder (HAND remains a pronounced consequence of HIV/AIDS despite improved life expectancies. This is often associated with several dysfunctions such as decrease of attention, mood alterations and psychomotor disturbances. Many factors, including age, gender, employment status, and psychiatric disorders, have been associated with HAND. Among the associated psychiatric disorders, depression is often more prevalent. It can influence not only quality of life, relationships and employment but also adherence to medical care. We assessed the prevalence of depression and its association with HAND among people living with
HIV in rural Southwestern Uganda.
Methods: This was a cross-sectional study that used Beck Depression Inventory-1 and International HIV Dementia
Scale to assess depression and HAND respectively. We defined depression with a score of > 10 and HAND with a cutoff score of ≤10. We conducted data analysis using STATA version 12, and Pearson Chi-square test and logistic regression to determine associations between depression and HAND. The level of statistical significance was set at p ≤ 0.05. Ethical approval and administrative clearance were obtained from relevant bodies.
Results: Of the 393 participants assessed for depression and HAND, 27% had depression and 58.3% screened positive for HAND. All levels of depression were more prevalent among female participants. We found a significant association between depression and HIV associated neurocognitive disorders (χ2 (3) = 9.0538 p = 0.029).
Conclusion: Our findings confirmed a high prevalence of depression in individuals with HAND which is a major component of the disease burden. | en_US |
dc.description.sponsorship | Fogarty International Center, the Office of the Director of the National Institutes of Health, the National Institute of Mental Health, and the National Institute of Neurological Disorders and Stroke under Award Number D43 TW010128. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | BMC Psychiatry | en_US |
dc.subject | Beck depression inventory | en_US |
dc.subject | Depression | en_US |
dc.subject | HIV-associated neurocognitive disorder | en_US |
dc.subject | International HIV dementia scale | en_US |
dc.title | Depression and HIV associated neurocognitive disorders among HIV infected adults in rural southwestern Uganda: a cross-sectional quantitative study | en_US |
dc.type | Article | en_US |