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Effects of Physalis peruviana L. (leaf crude extracts) on blood glucose and functional biomarkers in streptozotocin-nicotinamide-induced diabetic rats
(Die Pharmazie-An International Journal of Pharmaceutical Sciences, 2024)Promoting antidiabetic phytomedicines necessitates evidence-based preclinical investigations, particularly in animal models. The present study investigated the validity of using the streptozotocin-nicotinamide-induced type ... -
Virological Non-Suppression, Non-Adherence and the Associated Factors Among People Living with HIV on Dolutegravir-Based Regimens: A Retrospective Cohort Study
(HIV/AIDS - Research and Palliative Care, 2024)Background: HIV is one of the leading causes of morbidity and mortality, with 39.0 million people living with HIV worldwide, 25.6 million of whom reside in the African region. Highly active anti-retroviral therapy (HAART) ... -
Total polyphenols and antihyperglycemic activity of aqueous fruits extract of Abelmoschus esculentus: Modeling and optimization of extraction conditions
(PloS one, 2021)Aqueous fruits extract of Abelmoschus esculentus (L.) Moench (Malvaceae) has been used traditionally in several communities to alleviate elevated blood glucose levels. However, optimized extraction conditions have not been ... -
Preliminary phytochemical investigation on Mama powder — an approved herbal antimalarial in Nigeria
(Am J Ethnomed, 2018)Malaria is an endemic disease in Africa where one out of four mortalities is reported regularly. Despite the discovery of artemisinin-combination therapy (ACT), high mortality rate persists due to chloroquine-resistant ... -
Effect of Ethanol Leaf Extract of Khat (Catha edulis forsk) on Prefrontal Cortex Oxidative Markers and Hematological Profile of Wistar Rats
(Journal of Scientific Research & Reports, 2021)Aim: This study evaluated the effect of ethanol leaf extract of Catha edulis on the prefrontal cortex oxidative markers and hematological profile of Wistar rats. Study Design: The study design was experimental. Place ... -
A review for selecting medicinal plants commonly used for malaria in Uganda
(African Journal of Pharmacy and Pharmacology, 2020)The menace of current cases of parasite resistance to antimalarial drugs, non- availability and accessibility, and the high costs of pharmaceutical products contribute to the high rate of medicinal plants consumption in ... -
Human Health Risk Assessment of Heavy Metals in Kampala (Uganda) Drinking Water
(Journal of Food Research, 2022)Levels of aluminium, arsenic, cadmium, chromium, copper, iron, mercury, manganese, nickel, lead and zinc in tap water, groundwater-fed protected spring and bottled water were determined. The cancer and non-cancer risks ... -
Provisional Classification of Wild Edible Fruits Based on their Nutrient Profiles
(Acta Scientific NUTRITIONAL HEALTH, 2023)Nutritional analyses of food have mainly focused on determining the nutritional composition. Few concentrate on their nutritional value. This study provisionally classified ten wild edible fruits (WEF) growing in the Teso ... -
Confronting the complexities of antimicrobial management for Staphyloccous aureus causing bovine mastitis: an innovative paradigm
(Irish Veterinary Journal, 2024)Globally, Mastitis is a disease commonly affecting dairy cattle which leads to the use of antimicrobials. The majority of mastitis etiological agents are bacterial pathogens and Staphylococcus aureus is the predominant ... -
Drug-related problems and associated factors among patients with kidney dysfunction at a tertiary hospital in southwestern Uganda: a prospective observational study
(BMC nephrology, 2023)Background: Kidney dysfunction is a common, progressive condition that is increasingly becoming a global public health issue. Because the kidneys are the major route for drug excretion, impaired renal function can change ... -
Development and Validation of ‘Prediction of Adverse Drug Reactions in Older Inpatients (PADROI)’ Risk Assessment Tool
(Clinical Interventions in Aging, 2022)Background: Adverse drug reactions (ADR) detection and prediction methods in hospitalized older adults remain imprecise. The identification of the risk factors for ADRs in this group of patients is crucial to develop ... -
Prevalence and factors associated with adverse drug reactions among heart failure patients hospitalized at Mbarara Regional Referral Hospital, Ugand
(BMC Cardiovascular Disorders, 2022)Background: Adverse drug reaction (ADR) of medications remains an obstacle to achieving optimal disease outcomes. This study aimed to assess the prevalence and associated factors of ADR among Heart failure (HF) patients ... -
An Ethics-based Approach to Global Health Research Part 2: Strategies for Overcoming Logistic and Implementation Challenges
(Research in Social and Administrative Pharmacy, 2020)With the growth of global pharmacy partnerships and collaborative research, particularly between high-income countries and low- or middle-income countries, it is necessary to establish best practices for fair and ethical ... -
Effects of Commercial Boifertilizers on Growth and Yield of Antimalarial Compounds of Artemi sia Annua
(International Journal of Plant & Soil Science, 2023)Introduction: Artemisia annua is a medicinal plant grown by Ugandan farmers in Kabale and Kabarole. It is particularly used in preparation of antimalarial herbal teas used to control and prevent malaria. The content of ... -
Laboratory and simulated semi-field larvicidal efficacy of Aframomum angustifolium (Sonn.) K. Schum and Tagetes patula essential oils against Anopheles gambiae
(Journal of Natural Pesticide Research, 2024)Introduction: Malaria is a vector-borne, important public health problem spread by mosquitoes in tropical regions. The use of synthetic insecticides for mosquito control has been linked to insecticide resistance and ... -
Mitigating the burden of adverse drug reactions in older inpatients: short commentary
(Aging Communications, 2022)Studies have consistently identified older age as a predictor of adverse drug reaction (ADR) and the related adverse. The safety data collected during the premarketing phase is lacking due to the omission of distinctive ... -
COVID-19 vaccine hesitancy: assessing the prevalence, predictors, and effectiveness of a community pharmacy based counseling interventio
(BMC Public Health, 2024)Background: Coronavirus disease (COVID-19) vaccine hesitancy is a global challenge. In low- and middle-income countries (LMICs), the problem has persisted despite vaccine availability and decreasing infections. In Uganda, ... -
Comparative Evaluation of the Anti-Inflammatory Properties of Methanol and Aqueous Crude Extracts of Apical leaves of Sida cuneifolia: An Ethnomedicinal Plan
(Journal of Complementary and Alternative Medical Research, 2023)Aims: This study aimed to assess and compare the yield, phytochemical compositions, and anti inflammatory properties of methanol and aqueous crude extracts derived from the Apical leaves of Sida cuneifolia. Study Design: ... -
Prevalence and factors associated with potential drug-drug interactions in prescriptions presented at private pharmacies in Mbarara city, southwestern Uganda
(BMC Pharmacology and Toxicology, 2023)Background: Drug-drug interactions (DDIs) influence the effectiveness of medication and thus determine the treatment outcomes of diseases managed with pharmacotherapy. This study aimed to determine the prevalence, severity, ... -
Self-harming behaviors and forensic systemrelated factors: an analysis of the Ontario review board database
(BMC psychiatry, 2023)Background: In Canada, ensuring public safety, and the safety and well-being of accused individuals under the jurisdiction of the provincial review board are very important. While previous studies have reported a significant ...