Department of Pharmacology: Recent submissions
Now showing items 1-20 of 57
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Antimicrobial Stewardship Programmes: Healthcare Providers’ Perspectives on Adopted Hospital Policies That Combat Antibacterial Resistance in Selected Health Facilities in Uganda
(Antibiotics, 2024)Background: This study aimed to determine healthcare providers’ perspectives on adopted hospital policies that support establishing antimicrobial stewardship programmes (ASPs) in selected health facilities in Uganda. ... -
Engaging healthcare students in innovative approaches for antimicrobial resistance containment
(Journal of Public Health in Africa, 2024)Antimicrobial resistance (AMR) occurs when organisms change over time and no longer respond to medicines making infections harder to treat.1 Antimicrobial resistance continues to impact global populations, increasing ... -
Prevalence and factors associated with surgical site infections among mothers after cesarean section at Mbarara Regional Referral Hospital, Uganda: an observational retrospective study
(Therapeutic advances in infectious disease, 2024-10-09)Background: The risk of infection following cesarean delivery is 5–20 times higher than that following normal delivery, contributing to 10% of pregnancy-related mortality. In 2019, Mbarara Regional Referral Hospital (MRRH) ... -
Antimicrobial Bioactivity and GC-MS Analysis of Different Extracts of Corchorus olitorius L Leaves
(e Scientific World Journal, 2022-09-20)Plants have been used for the treatment of infectious diseases among various communities worldwide with undeniable success. Corchorus olitorius L is used to treat various ailments including infections. However, there are ... -
Neurochemistry and Pharmacology of Addictions: An African Perspective
(2019)Neurochemistry deals with the chemistry of nervous system molecules such as neurotransmitters, autacoids, hormones and neuropeptides that direct functions of neurons. These chemicals modulate the central and peripheral ... -
Structural and In Silico Characterization of Small Molecules Isolated from Eichhornia crassipes
(Evidence-Based Complementary and Alternative Medicine, 2020)Eichhornia crassipes has been reported to have various medicinal properties including anticancer activities. The plant was collected from the Shire river in Malawi, and two cytotoxic compounds, benzene-1,4-diol and nonanedioic ... -
Khat (Catha edulis) and ethanol co-dependence modulate seizure expression in a pentylenetetrazol seizure model
(Journal of Ethnopharmacology, 2011)Ethnopharmacological relevance: Khat is a plant with psychostimulant properties whose parts, mainly leaves and twigs, are chewed for its euphoriant effects. Khat use and ethanol abuse are increasingly becoming global health ... -
Evaluation of the Mutagenic Potential of Artavol® Using the Ame’s Test
(European Journal of Medicinal Plants, 2024)Background: The worldwide increase in the use of herbal medicinal - products calls for their safety testing to protect the public from unintended hazardous effects. However, most are not tested, putting the public at risk. ... -
A Review of Breast Cancer Treatment Modalities in Uganda- an Appraisal of the Breast Cancer Diagnostic Process, Regulatory Approval and Supply System of Standardized Anti-Breast Cancer Medicines
( International Journal of Advanced Research, 2020)Breast cancer is the leading cause of cancer death among women and the third incident cancer in the world, contributing 1.7 million of the 17.2 million annual incident cancer cases. For Uganda, breast cancer is the third ... -
The effect of prescription patterns on the performance of the pharmacy department of a Regional Referral Hospital, Uganda
(Journal of Pharmaceutical Policy and Practice, 2024)Background: Poor drug prescription patterns (PP) result in irrational medicine use, avoidable stock outs and drug expiries. Objective: This study primarily assessed the effects of PP on the performance of the pharmacy ... -
Immuno-Kachiks formula immunomodulates and ameliorates hepatic damage induced by monosodium glutamate in rats
(Heliyon, 2024)The immune system plays a vital role in controlling liver fibrosis and enhancing the pathogenesis of liver inflammation. Monosodium glutamate is a common flavor-enhancement food additive. This study evaluated the ... -
From Toxins to Drugs: Chemistry and Pharmacology of Animal Venom and other Secretions
(Online Journal of Complementary & Alternative Medicine, 2019)Animal secretions are currently proving more than before to be one of the best sources of drugs for current and future health complications. Well managed and optimized, their chemical compounds can as well be used to prevent ... -
African Progress in Drug Development Chemistry; a 100 Years Update
(2018)Africa is currently very active in the search for drugs particularly with focus on the preclinical phases of drug discovery. This work aimed at determining the extent to which Africa has gone with research and studies in ... -
Frogs and Lizards as Potential Drug Sources- a Mini Review
(Current Trends in Complementary and Alternative Medicine, 2018)Today, the world is heavily weighed down by emerging health complications which are exacerbated by the emergency of Multi Drug Resistant (MDR) microorganisms. This is happening despite the search for new and better drugs ... -
Toxicity Protocols for Natural Products in the Drug Development Process
(Poisonous Plants and Phytochemicals in Drug Discovery, 2020)Natural products are less toxic than synthetic compounds because of the adaption of humans and animals through exposure over time, which has enabled them to develop detoxification mechanisms [1]. Phytochemicals are extracted ... -
Chemical and Pharmacological Mechanisms of Plant-Derived Neurotoxins
(Poisonous Plants and Phytochemicals in Drug Discovery, 2020)The nervous system (NS) comprises the central and peripheral divisions. While the central nervous system (CNS) consists mainly of the brain and spinal cord, the peripheral nervous system (PNS) is subdivided into the somatic ... -
A cross-sectional assessment of the effects of select training modalities on vaccine cold chain management
(Journal of Pharmaceutical Policy and Practice, 2024)Background: Vaccines offer arguably the most cost-effective public health intervention. Vaccine supply chain management which is a critical building block faces many Human resources challenges mainly due to the special ... -
Postgraduate medical trainees at a Ugandan university perceive their clinical learning environment positively but differentially despite challenging circumstances: a cross-sectional stud
(BMC Medical Education, 2023)Purpose: The clinical learning environment is an essential component in health professions’ education. Data are scant on how postgraduate trainees in sub‑Saharan Africa perceive their medical school learning environments, ... -
Assessment of Bacterial Contamination and Antibiotic Susceptibility Patterns of Bacteria Isolated from Milk collected from Biharwe in Mbarara District: Cross-Sectional Study
(Journal of Veterinary Medicine and Surgery, 2022)Milk and dairy products are important source of vital nutrients for human beings. The unique composition and properties make milk an excellent medium for bacterial growth and source of bacterial infection. Milk borne ... -
Physicochemical, phytochemical and pharmacognostical parameters of a herbal plant Dracaena steudneri Engl.
(Journal of Pharmacognosy and Phytotherapy, 2023)Dracaena steudneri Engl. (family Dracaenaceae) has been used in managing various health conditions. This study evaluated its pharmacognostic, physicochemical and phytochemical parameters. The physicochemical analysis was ...
