Research Articles: Recent submissions
Now showing items 41-52 of 52
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Effects of Herbal Medicine Use on Adherence to Conventional Anticancer Drugs
(European Journal of Medicinal Plants, 2020)Background: Use of herbal medicines alongside conventional anticancer drugs is common among cancer patients. This may potentially cause reduced adherence to conventional anti-cancer drugs, unpredictable side effects and ... -
Evaluation of Sub-acute and Sub Chronic Toxicity Profile of the Aqueous Leaf Crude Extract of Melanthera Scandens (Schumach & Thonn) in Wistar Rats
(Journal of Complementary and Alternative Medical Research, 2019)Aims: Although Melanthera scandens is a plant widely used in traditional medicine for the management of seizures, stomach ulcers and sores, dysmenorrhea, diabetes and malaria, there was scanty information about its safety. ... -
Chronic khat (Catha edulis) and alcohol marginally alter complete blood counts, clinical chemistry, and testosterone in male rats
(Journal of Experimental Pharmacology, 2013)Introduction: Khat (Catha edulis) is a recreational psychoactive drug with psychostimulant properties. While the use of this drug is widespread in eastern Africa, including the Horn of Africa, surveys and anecdotal data ... -
Anti-fertility activity of aqueous root bark extracts of Asparagus africanus Lam and Annona senegalensis Pers combination on female Sprague Dawley rats
(African Journal of Pharmacy and Pharmacology, 2019)Many rural and poor women have now resorted to use of potential medicinal plants as a means of fertility control. Asparagus africanus Lam and Annona senegalensis Pers are some of the plants used for this purpose. The ... -
Acute and sub-acute toxicity of Echinops kebericho decoction in rats
(BMC Complementary Medicine and Therapies, 2020)Background: Echinops kebericho is widely used for treatment of a variety of diseases including infectious, noninfectious disease and fumigation during child birth. Antibacterial, antimalarial, anti-leshimania, anti-diarrheal ... -
Antibacterial Activities of Echinops kebericho Mesfin Tuber Extracts and Isolation of the Most Active Compound, Dehydrocostus Lactone
(Frontiers in Pharmacology, 2021-01-25)Echinops kebericho Mesfin is traditionally used for the treatment of various infectious diseases. This study investigated antibacterial activity of the essential oil (EO) and the different fractions of ethanol extract. The ... -
Chemical constituents and evidence-based pharmacological properties of Physalis peruviana L.: An overview
(Journal of Herbmed Pharmacology, 2021-01-21)Physalis peruviana L. is among plant species possessing evident nutritional, nutraceutical, and commercial interests. This review highlights the complexity of the chemical composition supporting the multiple pharmacotherapeutic ... -
Suboptimal Antiretroviral Drug Levels and Virologic Failures among PLHIV at a Rural Referral Hospital in South Western Uganda: A Descriptive Crosssectional Study.
(Research square, 2020)Background: Achieving favorable HIV treatment outcomes is a major challenge, particularly due to non-adherence and consequent sub-therapeutic plasma antiretroviral drug levels. This is often complicated by the development ... -
Projection neurons in the cortex and hippocampus: differential effects of chronic khat and ethanol exposure in adult male rats
(Journal of Experimental Pharmacology, 2016)Background: Recent evidence suggests that many individuals who chew khat recreationally also drink ethanol to offset the stimulating effect of khat. The objective of this study was to describe the separate and interactive ... -
Essential oils as topical anti-infective agents: A systematic review and meta-analysis
(Complementary therapies in medicine, 2019)Objective: This study summarized evidence on efficacy and safety of essential oils (EOs) in the treatment of topical infections. Design and Setting: Systematic review of clinical trials conducted and reported in accordance ... -
The availability of six tracer medicines in private medicine outlets in Uganda
(Journal of Pharmaceutical Policy and Practice, 2014)Objectives: Many low income countries struggle to provide safe and effective medicines due to poor public health care infrastructure, budgetary constraints, and lack of human resource capacity. Private sector pharmacies ... -
The Analgesic and Antiplasmodial Activities and Toxicology of Vernonia amygdalina
(Journal of medicinal food, 2008)Vernonia amygdalina possesses several bioactive compounds and is used in traditional medicines of southwestern Uganda, along with other regions. Its analgesic potential has not been investigated thus far. The present study ...