Research articles
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Effectiveness of preoperative bath using chloroxylenol antiseptic soap on the incidence of post emergency cesarean section surgical site infection at Mbarara Regional Referral hospital, Uganda: a randomized controlled trial
(Pan African Medical Journal, 2022)Introduction: Surgical Site Infections (SSIs) constitute 15%-45% of hospital acquired infections in sub-Saharan Africa. Cesarean section (CS) increases the risk of developing sepsis by 5-20 times and is highest when the ... -
Iatrogenic Female Genitourinary Fistula in Uganda: Etiology, Twelve-Year Trends, and Risk Factors for Development Following Cesarean Section
(International Journal of Women's Health, 2024)Purpose: To describe the magnitude and trend of the iatrogenic genitourinary fistula in Uganda, and the risk factors for development following the Cesarean Section (CS). Methods: A retrospective review of charts of women ... -
Determinants of quality antenatal care use in Kenya: Insights from the 2022 Kenya Demographic and Health Survey
(PLOS Global Public Health, 2024)Provision of quality antenatal care (ANC) is important to reduce maternal and newborn fatalities worldwide. However, the use of quality ANC by women of reproductive age and associated factors remain unclear in many developing ... -
Optimizing Vital Sign Monitoring in Resource-Constrained Maternal Care: AnRL-Based Restless Bandit Approach
(arXiv, 2024)Maternal mortality remains a significant global public health challenge. One promising approach to reducing maternal deaths occurring during facility-based childbirth is through early warning systems, which require the ... -
Amniotic Fluid Bacterial Colonization, Antibiotic Susceptibility, and Associated Factors Among Women With Premature Rupture of Membranes at Mbarara Regional Referral Hospital, Southwestern Uganda
(Cureus, 2024)Background: Amniotic fluid bacterial colonization in premature rupture of membranes (PROM) is known to initiate labor and lead to postpartum endometritis and early-onset neonatal sepsis. We determined the prevalence and ... -
Associations Between Non-communicable Diseases and Obstetric Complications: A Retrospective Records Review at a Tertiary Referral Hospital in Uganda
(Cureus, 2024)Objective: Non-communicable diseases (NCDs) increasingly contribute to maternal morbidity and mortality. We determined the association between NCDs and obstetric complications at Mbarara Regional Referral Hospital (MRRH) ... -
Prevalence and Factors Associated With Abnormal Cerebroplacental Ratio Among Women With Hypertensive Disorders of Pregnancy at a Tertiary Referral Hospital in Southwestern Uganda
(Journal of Pregnancy, 2024)Background: Hypertensive disorders of pregnancy (HDP) are associated with placental insufficiency and adverse perinatal outcomes—over half (58.9%) of women with HDP at Mbarara Regional Referral Hospital (MRRH) have adverse ... -
HELLP syndrome and associated factors among pregnant women with preeclampsia/ eclampsia at a referral hospital in southwestern Uganda: a cross-sectional study
(BMC Pregnancy and Childbirth, 2024)Background: Hemolysis Elevated Liver Enzymes Low Platelets (HELLP) syndrome, a complication of preeclampsia/ eclampsia, is associated with severe maternal morbidity and mortality. In resource-limited settings, such as ... -
Prevalence and factors associated with severe anaemia post-caesarean section at a tertiary Hospital in Southwestern Uganda
(BMC Pregnancy and Childbirth, 2021)Background: Severe anaemia after caesarean section adversely affects the woman and the new-born. While prenatal anaemia is extensively studied, the literature on post-caesarean section anaemia is limited and characteristics ... -
Adverse Perinatal Outcomes Among Teenage Mothers Delivering at a Tertiary Referral Hospital in Southwestern Uganda: Prevalence and Associated Factor
(Cureus, 2024)Introduction: Each year, millions of teenagers in low-resource areas experience unintended pregnancies, many of which result in childbirth. These pregnancies often carry an increased risk of negative perinatal outcomes. ... -
The silent threat: investigating the incidence and clinical characteristics of pre-eclampsia and eclampsia in women from tertiary care hospitals of the Democratic Republic of Congo
(Annals of Medicine and Surgery, 2024)Background: Pre-eclampsia and eclampsia are medical conditions that can cause severe complications, such as maternal and foetal morbidity and mortality. This study aimed to assess the incidence and characteristics of ... -
FOXP3serum concentration; a likely predictor of CIN and cervical cancer: Secondary analysis from a case control study at a clinic in South western Uganda
(Gynecologic Oncology Reports, 2024)Biomarkers including Forkhead/ winged-helix transcription factor boxP3 have been proposed in immune-histochemical techniques to diagnose cervical lesions, but can be objectively quantified and measured in blood using methods ... -
Outcomes of a honey and olive oil-based dressing material on wounds of women that have had a caesarean section in south-western Uganda
(International Wound Journal, 2024)Postpartum sepsis following caesarean sections among women in Uganda remains a risk. However, erratic supplies of standard dressing material make the risk a reality. Alternative wound dressing materials, therefore, remain ... -
Impact of postpartum maternal fever or hypothermia on newborn and early infant illness and death in Southwestern Uganda
(BMC Pregnancy and Childbirth, 2024)Background: Deaths occurring during the neonatal period contribute close to half of under-five mortality rate (U5MR); over 80% of these deaths occur in low- and middle-income countries (LMICs). Poor maternal antepartum and ... -
Prevalence of and Factors Associated with Adverse Maternal Obstetrical Events Among Teenage Mothers Delivering in a Tertiary Referral Hospital in Southwestern Uganda
(Cureus, 2024)Introduction: Many female teenagers in low-resource settings conceive, of which half are unplanned and end in many deaths in sub-Saharan Africa, accounting for the majority of the cases. Teenage pregnancy is associated ... -
Association between metabolic syndrome and cervical cancer among women in Southwestern Uganda: A case-control study
(Gynecologic Oncology Reports, 2024)Objective: To determine the association between MetS and its components with cervical cancer among women in South-western Uganda. Methods: We conducted an unmatched case-control study on470 participants in a1:2case-to-control ... -
Transition to Motherhood and Lived Experiences of Teenage Mothers Delivering in Kasese and Bundibugyo Districts, Western Uganda
(Cureus, 2024)Introduction: A large number of teenagers in low-resource settings experience pregnancy, with a significant number of these cases happening in sub-Saharan Africa. Teenage pregnancy is associated with unique physical and ... -
The epidemiology and risk factors for postnatal complications among postpartum women and newborns in southwestern Uganda: A prospective cohort study
(PLOS Global Public Health, 2024)Sub-Saharan Africa accounts for two-thirds of the global burden of maternal and newborn deaths. Adverse outcomes among postpartum women and newborns occurring in the first six weeks of life are often related, though data ... -
Providers and women’s perspectives on opportunities, challenges and recommendations to improve cervical cancer screening in women living with HIV at Mbarara Regional Referral Hospital: a qualitative study
(BMC Women's Health, 2024)Background: Cervical cancer screening uptake remains low despite being a critical prevention method for adult women living with HIV(WLHIV). These women experience greater incidence and persistence of high-risk human ... -
Maternal HIV infection drives altered placental Mtb-specific antibody transfer
(Frontiers in Microbiology, 2023)Introduction: Placental transfer of maternal antibodies is essential for neonatal immunity over the first months of life. In the setting of maternal HIV infection, HIV-exposed uninfected (HEU) infants are at higher risk ...
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