Increasing use of interferon gamma release assays among children ≥2 years of age in a setting with low tuberculosis prevalence

Abstract

US guidelines recommend interferon gamma release assays (IGRAs) for diagnosis of tuberculosis infection in children. In this retrospective cohort study, IGRA use in children 2–17 years of age increased substantially between 2015–2021. Testing in inpatient/subspecialty settings (vs primary care), public (vs private) insurance, lower age, and non-English preferred language were associated with increased odds of receiving an IGRA