| dc.contributor.author | Gumbi, Bhekumuzi P. | |
| dc.contributor.author | Moodley, Brenda | |
| dc.contributor.author | Birungi, Grace | |
| dc.contributor.author | Ndungu, Patrick G. | |
| dc.date.accessioned | 2021-04-26T13:43:00Z | |
| dc.date.available | 2021-04-26T13:43:00Z | |
| dc.date.issued | 2016-10-26 | |
| dc.identifier.citation | Gumbi, B. P., Moodley, B., Birungi, G., & Ndungu, P. G. (2017). Detection and quantification of acidic drug residues in South African surface water using gas chromatography-mass spectrometry. Chemosphere, 168, 1042-1050. | en_US |
| dc.identifier.uri | http://ir.must.ac.ug/xmlui/handle/123456789/641 | |
| dc.description.abstract | A method was optimized for derivation, separation, detection and quantification of salicylic acid, acetylsalicylic acid, nalidixic acid, ibuprofen, phenacetin, naproxen, ketoprofen, meclofenamic acid and diclofenac in surface water using gas chromatography-mass spectrometry. For most of the acidic drugs, recovery was in the range 60e110% and the percent standard deviation was below 15% for the entire method, with limits of detection ranging from 0.041 to 1.614 mg L_1. The developed method was applied in the analysis of acidic drugs in Umgeni River system, KwaZulu-Natal South Africa. All of the selected acidic drugs were detected and quantified, their concentration in Umgeni River system ranged from 0.0200 to 68.14 mg L_1. | en_US |
| dc.description.sponsorship | Water Research Commission of South Africa. BP Gumbi acknowledges the NRF. | en_US |
| dc.language.iso | en_US | en_US |
| dc.publisher | Chemosphere | en_US |
| dc.subject | Acidic drugs | en_US |
| dc.subject | Method validation | en_US |
| dc.subject | Derivatization | en_US |
| dc.subject | GC-MS | en_US |
| dc.subject | Surface water | en_US |
| dc.subject | Umgeni River | en_US |
| dc.title | Detection and quantification of acidic drug residues in South African surface water using gas chromatography-mass spectrometry | en_US |
| dc.type | Article | en_US |
