Faculty of Medicine: Recent submissions
Now showing items 201-220 of 2030
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Impact of rapid diagnostic tests for the diagnosis and treatment of malaria at a peripheral health facility in Western Uganda: an interrupted time series analysis
(Malaria journal, 2015)Background: The World Health Organization recommends that all suspected malaria cases receive a parasitological diagnosis prior to treatment with artemisinin-based combination therapy. A recent meta-analysis of clinical ... -
Participant perspectives on incentives for TB preventative therapy adherence and reduced alcohol use: A qualitative study
(PLOS Global Public Health, 2024)Economic incentives to promote health behavior change are highly efficacious for substance use disorders as well as increased medication adherence. Knowledge about participants’ experiences with and perceptions of incentives ... -
High Rate of Loss to Follow-Up Among Patients Undergoing Treatment for Premalignant Cervical Lesions at Mbarara Regional Referral Hospital, Southwestern Uganda: A Retrospective Cohort Study
(Cureus, 2023)Background: For a cervical cancer control program to be effective in reducing the incidence of the disease, there should be high compliance to treatment and follow-up of women diagnosed with precursor lesions. Screening ... -
Exploring the burden of postpartum depression in urban Bangladesh: Prevalence and its associations with pregnancyrelated factors from a cross‐sectional study
(Health Science Reports, 2024)Background and Aims: Postpartum depression (PPD) is a globally recognized public health concern, yet research focusing on women in urban areas of Bangladesh remains unexplored. This study aimed to address this research gap ... -
An exploratory study on becoming a traditional spiritual healer among Baganda in Central Uganda
(PLOS Global Public Health, 2024)Traditional medicinal knowledge and healing practices of indigenous spiritual healers play important roles in health care, and contribute towards achieving Universal Health Care. Traditional spiritual healers (TSHs) are ... -
The utility of resting pulse rate in defining high blood pressure among adolescents in Mbarara municipality, Uganda
(ournal of Human Hypertension, 2021)High resting pulse rate (RPR) is associated with adverse cardiovascular events and could be used as a marker of cardiovascular health. We determined the correlation between RPR and blood pressure (BP); and its accuracy in ... -
Alcohol Consumption in Ugandan HIV-Infected Household-Brewers Versus Non-Brewers
(AIDS and Behavior, 2016)The brewing of alcohol in Ugandan households is common, yet little is known about its relationship with alcohol consumption in HIV-infected individuals. We performed a cross-sectional analysis to assess the association ... -
Validation of the Intracerebral Hemorrhage Score in Uganda A Prospective Cohort Study
(Stroke, 2018)Background and Purpose: Rates of intracerebral hemorrhage (ICH) are estimated to be highest globally in sub-Saharan Africa. However, outcomes of ICH are poorly described and standard prognostic markers for ICH have not ... -
Alcohol Use and Food Insecurity Among People Living with HIV in Mbarara, Uganda and St. Petersburg, Russia
(AIDS and Behavior, 2017)Food insecurity (FI) is a documented problem associated with adverse health outcomes among HIV-infected populations. Little is known about the relationship between alcohol use and FI. We assessed whether heavy alcohol use ... -
Agreement Between Measures of Adherence to Isoniazid Preventive Therapy Among People With HIV in Uganda
(In Open forum infectious diseases, 2022)Background: Isoniazid (INH) preventative therapy is recommended for people with HIV (PWH) in resource-constrained settings. Valid measures are needed to assess adherence. We aimed to examine agreement between measures ... -
Social Desirability Bias Impacts Self-Reported Alcohol Use Among Persons With HIV in Uganda
(Alcoholism: Clinical and Experimental Research, 2019)Background: Self-report is widely used to assess alcohol use in research and clinical practice, but may be subject to social desirability bias. We aimed to determine if social desirability impacts self-reported alcohol ... -
Unhealthy Alcohol Use Is Associated With Suboptimal Adherence to Isoniazid Preventive Therapy in Persons With HIV in Southwestern Ugand
(JAIDS Journal of Acquired Immune Deficiency Syndromes, 2022)Background: Unhealthy alcohol use is associated with increased progression to tuberculosis (TB) disease, but its effect on adherence to isoniazid (INH) preventive therapy is not known. Methods: This was a prospective ... -
Unhealthy Alcohol Use is Associated with Monocyte Activation Prior to Starting Antiretroviral Therapy
(Clinical and Experimental Research, 2015)Background: Alcohol use may accelerate HIV disease progression, but the plausible biological mechanisms have not been clearly elucidated. Methods: HIV-positive persons who were not on antiretroviral therapy (ART) completed ... -
Alcohol Use and HIV Disease Progression in an Antiretroviral Naive Cohort
(JAIDS Journal of Acquired Immune Deficiency Syndromes, 2018)Background: Alcohol use has been shown to accelerate disease progression in experimental studies of simian immunodeficiency virus in macaques, but the results in observational studies of HIV have been conflicting. Methods: ... -
Alcohol Consumption and Tryptophan Metabolism Among People with HIV Prior to Antiretroviral Therapy Initiation: The Uganda ARCH Cohort Study
(Alcohol and Alcoholism, 2022)Aims: Alcohol is hypothesized to have effects on the kynurenine pathway of tryptophan catabolism, a potential mechanism for alcohol-induced depression and aggression. A biomarker of this pathway, the plasma kynurenine to ... -
The Relationship Between Spirituality/Religiousness and Unhealthy Alcohol Use Among HIV-Infected Adults in Southwestern Ugand
(AIDS and Behavior, 2018)HIV and alcohol use are two serious and coexisting problems in sub-Saharan Africa. We examined the relationship between spirituality and/or religiousness (SR) and unhealthy alcohol use among treatment-naıve HIV-infected ... -
Assessing the interaction between depressive symptoms and alcohol use prior to antiretroviral therapy on viral suppression among people living with HIV in Rural Uganda
(AIDS care, 2020)Although there is evidence of individual associations between depressive symptoms and hazardous alcohol use with suboptimal antiretroviral therapy (ART) adherence among people living with HIV (PLWH), few studies have ... -
Financial incentives for reduced alcohol use and increased isoniazid adherence during tuberculosis preventive therapy among people with HIV in Uganda: an open-label, factorial randomised controlled trial
(The Lancet Global Health, 2023)Background: Alcohol use is common among people with HIV and is a risk factor for tuberculosis disease and non-adherence to isoniazid preventive therapy (IPT). Few interventions exist to reduce alcohol use and increase IPT ... -
A Review of Breast Cancer Treatment Modalities in Uganda- an Appraisal of the Breast Cancer Diagnostic Process, Regulatory Approval and Supply System of Standardized Anti-Breast Cancer Medicines
( International Journal of Advanced Research, 2020)Breast cancer is the leading cause of cancer death among women and the third incident cancer in the world, contributing 1.7 million of the 17.2 million annual incident cancer cases. For Uganda, breast cancer is the third ... -
Labour Care Guide implementation as a decision- making tool for monitoring labour among healthcare providers in Uganda: protocol for a mixed- methods study
(BMJ Open, 2024)Introduction: The new WHO Labour Care Guide (LCG), also regarded as the ‘next- generation partograph’, is a core component of 2018 WHO consolidated guidelines on intrapartum care for positive childbirth experience. The ...