Mbarara University of Science and Technology Institutional Repository: Recent submissions
Now showing items 381-400 of 3211
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Retention in Care among HIV-Infected Patients in Resource-Limited Settings: Emerging Insights and New Directions
(Current Hiv/aids Reports, 2010)In resource-limited settings—where a massive scale up of HIV services has occurred in the last 5 years— both understanding the extent of and improving retention in care presents special challenges. First, retention in care ... -
Estimation of mortality among HIV-infected people on antiretroviral treatment in east Africa: a sampling based approach in an observational, multisite, cohort study
(The lancet HIV, 2015)Background: Mortality in HIV-infected people after initiation of antiretroviral treatment (ART) in resource-limited settings is an important measure of the effectiveness and comparative effectiveness of the global public ... -
Digital Health Screening in People With HIV in Uganda to Increase Alcohol Use Reporting: Qualitative Study on the Development and Testing of the Self-administered Digital Screener for Health
(JMIR formative research, 2022)Background: Alcohol consumption is a critical driver of the HIV epidemic worldwide, particularly in sub-Saharan Africa, where unhealthy alcohol use and HIV are prevalent. Brief alcohol interventions are effective in ... -
Diagnosing Kaposi’s Sarcoma (KS) in East Africa: how accurate are clinicians and pathologists?
(Infectious Agents and Cancer, 2012)HIV-associated KS is the most common reported malignancy in sub-Saharan Africa, and appropriate therapy of KS requires accurate diagnosis. In much of the region, however, KS diagnosis is limited to clinical suspicion without ... -
Contraceptive Use and Associated Factors among Women Enrolling into HIV Care in Southwestern Uganda
(Infectious diseases in obstetrics and gynecology, 2012)Background: Preventing unintended pregnancies among women living with HIV is an important component of prevention of mother-to-child HIV transmission (PMTCT), yet few data exist on contraceptive use among women entering ... -
Comparative analyses of published cost effectiveness models highlight critical considerations which are useful to inform development of new models
(Journal of medical economics, 2020)Background: Comparative analyses of published cost effectiveness models provide useful insights into critical issues to inform the development of new cost effectiveness models in the same disease area. Objective: The ... -
Cell Phone Availability and Usage for mHealth and Intervention Delivery to Persons Living With HIV in a Low-Resource Setting: Cross-sectional Study
(JMIR Formative Research, 2022)Background: HIV/AIDS is now a manageable chronic illness owing to effective antiretroviral therapy (ART), which involves routine follow-up care, including regular physical visits to the clinic. In the recent past, and in ... -
Task Shifting and Skin Punch for the Histologic Diagnosis of Kaposi’s Sarcoma in Sub-Saharan Africa: A Public Health Solution to a Public Health Problem
(Oncology, 2015)Fueled by HIV, sub-Saharan Africa has the highest incidence of Kaposi’s sarcoma (KS) in the world. Despite this, KS diagnosis in the region is based mostly on clinical grounds. Where biopsy is available, it has traditionally ... -
A qualitative analysis of self-management needs of adolescents and young adults living with perinatally acquired HIV in rural, southwestern Uganda
(PLOS Glob Public Health, 2024)The number of adolescents living with HIV remains high in sub-Saharan Africa with poorer HIV treatment outcomes among adolescents and young adults compared to individuals in other age groups. For adolescents and young ... -
Adding Fuel to the Fire: Alcohol’s Effect on the HIV Epidemic in Sub-Saharan Africa
(Current HIV/AIDS Reports, 2011)Alcohol consumption adds fuel to the HIV epidemic in sub-Saharan Africa (SSA). SSA has the highest prevalence of HIV infection and heavy episodic drinking in the world. Alcohol consumption is associated with behaviors such ... -
Tracking a sample of patients lost to follow-up has a major impact on understanding determinants of survival in HIV-infected patients on antiretroviral therapy in Africa
(Tropical Medicine & International Health, 2010)Objective: To date, data regarding the determinants of mortality in HIV-infected patients starting antiretroviral therapy (ART) in Africa have been primarily derived from routine clinical care settings practicing the public ... -
Feasibility and acceptability of using the novel urine-based FujiLAM test to detect tuberculosis: A multi-country mixed-methods study
(Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2022)Background: The novel urine-based FujiLAM test identifies tuberculosis in HIV-positive patients but may be challenging to use at point-of-care (POC). Objectives: We assessed the feasibility and acceptability of using the ... -
Unravelling patient pathways in the context of antibacterial resistance in East Africa
(BMC Infectious Diseases, 2023)Background: A key factor driving the development and maintenance of antibacterial resistance (ABR) is individuals’ use of antibiotics (ABs) to treat illness. To better understand motivations and context for antibiotic use ... -
Integration of HIV Testing in a Community Intervention for Tuberculosis Screening Among Household Contacts of Patients with Tuberculosis in Cameroon and Uganda
(JAIDS Journal of Acquired Immune Deficiency Syndromes, 2024)Introduction: People living with HIV are considered at higher risk of developing severe forms of tuberculosis (TB) disease. Providing HIV testing to TB-exposed people is therefore critical. We present the results of ... -
Prevalence of anti-leptospiral IgM and detection of pathogenic Leptospira species DNA in neonates presenting with clinical sepsis in Southwestern Uganda
(European Journal of Medical Research, 2022)Background: Leptospirosis is an emerging neglected zoonotic disease that presents with nonspecific signs/symptoms and it can be mistaken for other diseases. Owing to limited diagnostic capacity and unawareness, the data ... -
The effect of prescription patterns on the performance of the pharmacy department of a Regional Referral Hospital, Uganda
(Journal of Pharmaceutical Policy and Practice, 2024)Background: Poor drug prescription patterns (PP) result in irrational medicine use, avoidable stock outs and drug expiries. Objective: This study primarily assessed the effects of PP on the performance of the pharmacy ... -
Immuno-Kachiks formula immunomodulates and ameliorates hepatic damage induced by monosodium glutamate in rats
(Heliyon, 2024)The immune system plays a vital role in controlling liver fibrosis and enhancing the pathogenesis of liver inflammation. Monosodium glutamate is a common flavor-enhancement food additive. This study evaluated the ... -
Mental Health Challenges Among Children and Adolescents Associated With HIV Status Disclosure: A Systematic Review and Meta-Analysis Protocol
(Qeios, 2024)Background: Prenatally acquired HIV is highly prevalent among children and adolescents globally. HIV status disclosure to children is recommended to start from 8 years and older and has shown several benefits. However, HIV ... -
A ‘hidden problem’: Nature, prevalence and factors associated with sexual dysfunction in persons living with HIV/AIDS in Uganda
(Plos one, 2024)Background: We conducted a clinic-based cross-sectional survey among 710 people living with HIV/ AIDS in stable ‘sexual’ relationships in central and southwestern Uganda. Although sexual function is rarely discussed due ... -
Mycobacterium tuberculosis mixed infections and drug resistance in sub-Saharan Africa: a systematic review
(African Health Sciences,, 2022)Background: Sub-Saharan Africa, is a region that records high rates of TB infection. Mycobacterium tuberculosis mixed strain infection, especially when the strains involved are of different susceptibilities, is an area of ...