Clinical efficacy of chloroquine or sulfadoxine-pyrimethamine in children under five from south- western Uganda with uncomplicated falciparum malaria

Abstract

We conducted a 14-day study (during March- May 1998) to assess the efficacy of chloroquine and sulfadoxine-pyrimethamine (SP) for treating uncomplicated Plasmodium falciparum malaria in Uganda. Overall treatment failure rates were 43 (8 1.1%) of 53 chloroquine recipients and 16 (250%) of 64 SP patients. Strategies to improve the life-span of standard and affordable anti- malarial drugs are needed.

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Legros, D., Johnson, K., Houpikian, P., Makanga, M., Kabakyenga, J. K., Talisuna, A. O., & Taylor, W. R. J. (2002). Clinical efficacy of chloroquine or sulfadoxine-pyrimethamine in children under five from south-western Uganda with uncomplicated falciparum malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene, 96(2), 199-201.

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