Lab tests can be used to predict phosphatidylethanolmeasured high-risk alcohol use among people with HIV:

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dc.contributor.authorSilva,C. Espinosa da ,
dc.contributor.authorScheffler.A,
dc.contributor.authorFatch.R,
dc.contributor.authorMuyindike.W,
dc.contributor.authorEmenyonu N.I,
dc.contributor.authorJ. Adong .J,
dc.contributor.authorChamie .G
dc.contributor.authorNgabirano.G
dc.contributor.authorKekibiina.A,
dc.contributor.authorTumwegamire.A,
dc.contributor.authorMarson.K,
dc.contributor.authorBeesiga.B,
dc.contributor.authorKindoli.E,
dc.contributor.authorAllen I.E,
dc.contributor.authorHah J.A,
dc.date.accessioned2026-02-02T10:35:20Z
dc.date.issued2025-10-31
dc.description.abstractBackground: Unhealthy alcohol use is prevalent among persons with HIV (PWH) and is associated with adverse outcomes, but is underestimated partly due to use of self-reported measures prone to underreporting. Phosphatidyl ethanol (PEth) is a direct measure of past month alcohol consumption but is costly. We assessed whether lab and health data representing alcohol-associated physiologic changes could be leveraged with machine learning to predict PEth-measured high-risk alcohol use among PWH. Methods: We pooled baseline data from two studies among PWH in Uganda that measured PEth (N = 988), and classified PEth as no/low/moderate (Peth)
dc.description.sponsorshipThe National Institute on Alcohol Abuse and Alcoholism (grant number R01AA029962).
dc.identifier.citationEspinosa da Silva, C., Scheffler, A., Fatch, R., Muyindike, W., Emenyonu, N. I., Adong, J., ... & Drinkers’ Intervention to Prevent Tuberculosis (DIPT) Study and the Alcohol Drinkers’ Exposure to Preventive Therapy for TB (ADEPT-T) Study. (2026). Lab tests can be used to predict phosphatidylethanol-measured high-risk alcohol use among people with HIV: a proof-of-concept using machine learning. Alcohol and Alcoholism, 61(1), agaf078.
dc.identifier.urihttps://ir.must.ac.ug/handle/123456789/4206
dc.language.isoen
dc.publisherAlcohol and Alcoholism
dc.rightsAttribution-NonCommercial-NoDerivs 3.0 United Statesen
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/us/
dc.subjectscreening
dc.subjectdetection
dc.subjectalcohol biomarkers
dc.subjectprediction tool
dc.titleLab tests can be used to predict phosphatidylethanolmeasured high-risk alcohol use among people with HIV:
dc.title.alternativea proof-of-concept using machine learning
dc.typeArticle

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