Browsing Research Articles by Title
Now showing items 1-20 of 40
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Aflatoxin Susceptible Food Consumption Frequency, Prevalence, and Levels in Household Foodstuffs in Southwestern Uganda
(Journal of Food Quality, 2023)Contamination of household foodstu1s by a2atoxins has been associated with many illnesses, especially hepatocellular cancer and malnutrition. A2atoxins are toxins produced by fungi, especially Aspergillus 1avus and Aspergillus ... -
Antibiotic use among patients with febrile illness in a low malaria endemicity setting in Uganda.
(BioMed Central Ltd, 2011)Uganda embraced the World Health Organization guidelines that recommend a universal ‘test and treat’ strategy for malaria, mainly by use of rapid diagnostic test (RDT) and microscopy. However, little is known how increased ... -
Bioremedial potential of bacteria isolated from soil in automobile garages and fuel stations in Mbarara City, Southwestern Uganda
(Bioremediation Journal, 2024)The use of bacteria to clean up oil-contaminated soils is widely considered the most desirable bioremediation strategy. The majority of research has focused on contaminated soils in large oil-producing countries. However, ... -
CD4-T-Lymphocyte Reference Ranges in Uganda and Its Influencing Factors
(Laboratory Medicine, 2011)Background: Given the importance of CD4-T-lymphocyte monitoring in HIV/ART management, we established CD4/CD8 reference ranges in Uganda and studied factors associated with CD4/CD8 in a normal population. Methods: Blood ... -
Combating Lassa Fever in West African Sub-Region: Progress, Challenges, and Future Perspectives
(Viruses, 2023)Lassa fever (LF) is a rodent-borne disease that threatens human health in the sub-region of West Africa where the zoonotic host of Lassa virus (LASV) is predominant. Currently, treatment options for LF are limited and since ... -
Comparison of the Nutritional Status of Swiss Albino Mice Fed on Either a Purified or Cereal-Based Diet for 15 weeks
(Biochemistry Research International, 2023)Background: Laboratory animals are commonly fed on cereal-based diets (CBDs) whose nutrient composition is unknown and may confound the metabolic response to study interventions. Puri2ed diets such as AIN-93M are therefore ... -
Coping strategies for HIV and mental illness comorbidities among adult patients in southwestern Uganda
(Research square, 2022)Background: HIV and mental illness comorbidity remain one of the healthcare challenges with limited information and medical care attention. The co-existence of the two, result in poor coping thereby increasing vulnerability ... -
Corrigendum: TDP-43 and NEAT long non-coding RNA: Roles in neurodegenerative disease
(Frontiers in Cellular Neuroscience, 2022)“Understanding and ameliorating neurodegenerative diseases represents a key challenge for supporting the health span of the aging population. Diverse protein aggregates have been implicated in such neurodegenerative ... -
Cost-effectiveness of malaria microscopy and rapid diagnostic tests versus presumptive diagnosis: implications for malaria control in Uganda
(BioMed Central Ltd, 2011)Current Uganda National Malaria treatment guidelines recommend parasitological confirmation either by microscopy or rapid diagnostic test (RDT) before treatment with artemether-lumefantrine (AL). However, the cost-effectiveness ... -
CRISPR/Cas9 and next generation sequencing in the personalized treatment of Cancer
(Molecular Cancer, 2022)Background: Cancer is caused by a combination of genetic and epigenetic abnormalities. Current cancer therapies are limited due to the complexity of their mechanism, underlining the need for alternative therapeutic approaches. ... -
Cucumeropsis mannii seed oil (CMSO) ameliorates adipokines dysfunction and dyslipidemia in male Wistar rats exposed to Bisphenol-A
(BioRxiv, 2022)Bisphenol-A (BPA) and its analog are extensively utilized in the production of plastics which are rather ubiquitous in our environment. At high temperatures, BPA is leached into water and food packed in plastic containers. ... -
Cucumeropsis mannii seed oil ameliorates Bisphenol-A- induced adipokines dysfunctions and dyslipidemia
(Food Science & Nutrition, 2023)This study demonstrated the therapeutic potentials of Cucumeropsis mannii seed oil (CMSO) capable of alleviating BPA-induced dyslipidemia and adipokine dysfunction. In this study, we evaluated the effects of CMSO on adipokine ... -
Cucumeropsis mannii seed oil protects against bisphenol A-induced hepatotoxicity by mitigating inflammation and oxidative stress in rats
(RPS Pharmacy and Pharmacology Reports, 2024)Objectives: This study looked at how Cucumeropsis mannii seed oil (CMSO) affected male Wistar albino rats’ liver damage caused by bisphenol A (BPA). Methods: The standard HPLC method was used to assess the CMSO’s ... -
Dynamics of Plasmodium falciparum alleles in children with normal haemoglobin and with sickle cell trait in western Uganda
(El s e v i e r, 2008-07-31)We describe the diversity of Plasmodium falciparum populations in western Uganda and assess the role that asymptomatic malaria carriers with sickle cell trait (HbAS) may be playing on the Plasmodium population structure. ... -
Effect of Extraction Period on Total Phenolics, Total Flavonoids, and Antioxidant Capacity of Ugandan Camellia sinensis (L) Kuntze, Black Primary Grades and Green Tea
(Journal of Food Quality, 2023)Introduction: Globally, the consumption and production of tea are on the rise because of its beneficial constituents. Scarce literature exists on the e1ects of extraction periods on the contents of the biologically important ... -
Effect of Spice form and Extraction Period on Total Phenolic Content of Selected Ugandan Spices
(European Journal of Medicinal Plants, 2022-04-08)Introduction: Spice consumption is one of the globally recognized healthy nutritional practices. Most spices contain phenolic compounds that may prevent or prolong the onset of noncommunicable diseases. The harvesting, ... -
Effects of season and agro-ecological zone on the microbial quality of raw milk along the various levels of the value chain in Uganda
(Tropical Animal Health and Production, 2008-11-19)Dairy production in Uganda is pasture based and traditional Ankole cattle make up 80% of the cattle herd, reared in both pastoral and agropastoral ecological zones. Regardless of the zone, milk quality is lowest in production ... -
Elucidation of chemical profiles and molecular targets of Mondia whitei leave fractions bioactive as novel therapeutics: an in vitro and in silico assay
(Journal of Genetic Engineering and Biotechnology, 2022)Background: Mondia whitei root is often used in Africa as a local therapeutic agent for libido enhancement. The fractions of the M. whitei leaves (MWL) lack chemical characterization of their bioactive components and ... -
Genetic diversity in Plasmodium falciparum merozoite surface protein 1 and 2 coding genes and its implications in malaria epidemiology: a review of published studies from 1997–2007
(Journal of Vector Borne Diseases, 2009-04)A major characteristic of human malaria parasites is their genetic diversity and an increasing number of studies have been reported on the epidemiology of Plasmodium falciparum, mainly focusing on the polymorphism of ... -
In vitro antimycobacterial activity of medicinal plants Lantana camara, Cryptolepis sanguinolenta, and Zanthoxylum leprieurii
(Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2022)Background: Imperative need exists to search for new anti-TB drugs that are safer, and more effective against drug-resistant strains. Medicinal plants have been the source of active ingredients for drug development. However, ...
