Research Articles: Recent submissions
Now showing items 241-260 of 440
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Drugs for some but not all: inequity within community health worker teams during introduction of integrated community case management
(BMC health services research, 2014)Background: The Ugandan health system now supports integrated community case management (iCCM) by community health workers (CHWs) to treat young children ill with fever, presumed pneumonia, and diarrhea. During an iCCM ... -
Lung function and atherosclerosis: a cross‑sectional study of multimorbidity in rural Uganda
(BMC Pulmonary Medicine, 2022)Background: Chronic obstructive pulmonary disease (COPD) is a leading cause of global mortality. In high-income settings, the presence of cardiovascular disease among people with COPD increases mortality and complicates ... -
Longitudinal assessment of associations between food insecurity, antiretroviral adherence and HIV treatment outcomes in rural Uganda
(AIDS, 2015-11-02)Introduction: Food insecurity is a potentially important barrier to the success of antiretroviral treatment (ART) programs in resource-limited settings. We undertook a longitudinal study in rural Uganda to estimate the ... -
Lessons Learned From and Future Opportunities for Global Health Endeavors by 2 Academic Gastroenterology Units
(Gastroenterology, 2019-11-01) -
Diminishing Availability of Publicly Funded Slots for Antiretroviral Initiation among HIV-Infected ART-Eligible Patients in Uganda
(PLoS ONE, 2010-11)Background: The impact of flat-line funding in the global scale up of antiretroviral therapy (ART) for HIV-infected patients in Africa has not yet been well described. Methods: We evaluated ART-eligible patients and ... -
Knowledge of obstetric danger signs and birth preparedness practices among women in rural Uganda
(Reproductive Health, 2011-11-06)Background: Improving knowledge of obstetric danger signs and promoting birth preparedness practices are strategies aimed at enhancing utilization of skilled care in low-income countries. The aim of the study was to explore ... -
Introduction of mobile phones for use by volunteer community health workers in support of integrated community case management in Bushenyi District, Uganda: development and implementation process
(BMC Health Services Research, 2014-05-12)Background: A substantial literature suggests that mobile phones have great potential to improve management and survival of acutely ill children in rural Africa. The national strategy of the Ugandan Ministry of Health calls ... -
Real-time Adherence Monitoring of Antiretroviral Therapy Among HIV-infected Adults and Children in Rural Uganda
(AIDS, 2013)A real-time wireless electronic adherence monitor(EAM) and weekly self-report of missed doses via interactive voice response (IVR) and short message service (SMS) queries were used to measure ART adherence in 49 adults and ... -
Intimate partner violence, spouse extramarital affairs, and depression among women in rural Uganda
(Research square, 2021-04-12)Background: Depression is highly prevalent among women compared to men. Women in rural areas are more at risk of depression compared to their peers in urban areas. Some of the factors associated with depression among married ... -
Diagnostic accuracy of Xpert MTB/RIF Ultra for tuberculous meningitis in HIV-infected adults: a prospective cohort study
(The Lancet Infectious Diseases, 2017-09-14)Background: WHO recommends Xpert MTB/RIF as initial diagnostic testing for tuberculous meningitis. However, diagnosis remains difficult, with Xpert sensitivity of about 50–70% and culture sensitivity of about 60%. We ... -
Internalized Stigma, Social Distance, and Disclosure of HIV Seropositivity in Rural Uganda
(Annals of Behavioral Medicine, 2013-05-21)Background: HIV is highly stigmatized, compromising both treatment and prevention in resource-limited settings. Purpose: We sought to study the relationship between internalized HIV-related stigma and serostatus disclosure ... -
Individual and health facility factors and the risk for obstructed labour and its adverse outcomes in south-western Uganda
(BMC pregnancy and childbirth, 2011)Background: Obstructed labour is still a major cause of maternal morbidity and mortality and of adverse outcome for newborns in low-income countries. The aim of this study was to investigate the role of individual and ... -
Increased Systemic Inflammation and Gut Permeability Among Women With Treated HIV Infection in Rural Uganda
(The Journal of Infectious Diseases, 2018-04-28)In a cohort of human immunodeficiency virus (HIV)–infected individuals and age- and sex-matched HIV-uninfected comparators, we assessed soluble CD14 (sCD14), sCD163, interleukin 6, intestinal fatty acid binding protein ... -
HIV-Associated Cryptococcal Meningitis Occurring at Relatively Higher CD4 Counts
(The Journal of infectious diseases, 2019)Background. Cryptococcal meningitis can occur in persons with less-apparent immunosuppression. We evaluated clinical characteristics and outcomes of persons with HIV-related Cryptococcus presenting with higher CD4 ... -
HIV Infection, Pulmonary Tuberculosis, and COPD in Rural Uganda: A Cross-Sectional Study
(Lung, 2018)Purpose HIV is associated with chronic obstructive pulmonary disease (COPD) in high resource settings. Similar relationships are less understood in low resource settings. We aimed to estimate the association between HIV ... -
Exploring drivers and barriers to the utilization of community client-led ART delivery model in South-Western Uganda: patients’ and health workers’ experiences
(BMC health services research, 2021)Background: In an effort to accommodate the growing number of HIV clients, improve retention in care and reduce health care burden, the differentiated service delivery (DSD) models were introduced in 2014. One such model, ... -
Impact of CD8+ T Cell Activation on CD4+ T Cell Recovery and Mortality in HIV-infected Ugandans Initiating Antiretroviral Therapy
(AIDS, 2011)Objectives—To assess whether T cell activation independently predicts the extent of CD4+ T cell recovery and mortality in HIV-infected Ugandans initiating antiretroviral therapy (ART). Design—Prospective cohort ... -
Incidence and Predictors of Hypertension in Adults with HIV Initiating Antiretroviral Therapy in Southwestern Uganda
(Journal of hypertension, 2016-10-01) -
Determinants of two-year mortality among HIV positive patients with Cryptococcal meningitis initiating standard antifungal treatment with or without adjunctive dexamethasone in Uganda
(PLOS NEGLECTED TROPICAL DISEASES, 2020-11-30)Globally, early initiation of antiretroviral therapy for HIV led to a reduction in the estimated mortality from cryptococcal meningitis (CCM) from 624,700 in 2009 to 181,100 in 2014. However, CCM remains one of the leading ... -
Determinants of Mortality in a Combined Cohort of 501 PatientsWith HIV-Associated Cryptococcal Meningitis: Implications for Improving Outcomes
(Clinical Infectious Diseases, 2013-12-06)Background: Cryptococcal meningitis (CM) is a leading cause of death in individuals infected with human immunodeficiency virus (HIV). Identifying factors associated with mortality informs strategies to improve outcomes. Methods: ...