Browsing Research Articles by Title
Now showing items 1-20 of 103
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AmpC-BETA Lactamases among Enterobacteriaceae Isolated at a Tertiary Hospital, South Western Uganda
(British biotechnology journal, 2014)Aim—To characterize AmpC-beta lactamases among Enterobacteriaceae isolates from clinical samples at Mbarara Regional Referral Hospital. Study Design—Laboratory-based descriptive cross-sectional study Place and Duration ... -
Anti-Mycobacterial Activity of Medicinal Plant Extracts Used in the Treatment of Tuberculosis by Traditional Medicine Practitioners in Uganda
(Pharmacology & Pharmacy, 2023)Tuberculosis (TB) remains a public health challenge and one of the leading causes of death worldwide. TB is preventable and curable. However, treatment of tuberculosis has continued to be difficult as a result of rapid ... -
Antifungal Susceptibility Patterns of Vulvovaginal Candida species among Women Attending Antenatal Clinic at Mbarara Regional Referral Hospital, South Western Uganda
(British microbiology research journal, 2015)Aims—To identify the Candida species that cause vulvovaginal candidiasis and determine their antifungal susceptibility patterns. Study Design—This was a cross-sectional study. Place and Duration of Study—The study was ... -
Antimicrobial resistance at the human–animal interface in the Pastoralist Communities of Kasese District, South Western Uganda
(Scientific Reports, 2020-09-07)Intensive usage of antimicrobials in the management of animal diseases leads to selection for resistance among microorganisms. This study aimed to assess antimicrobial use and to describe factors associated with the ... -
Antimicrobial Resistance of Neisseria gonorrhoeae Isolated from Out Patients Presenting with Urethral and Vaginal Discharges at Mbarara Regional Referral Hospital
(Journal of Advances in Medicine and Medical Research, 2019-08-16)Background: Gonococcus is one of the most common sexually transmitted diseases in developing countries and it has become a global health burden, hence a need for effective treatment. However, there is growing trend of ... -
Antimicrobial Resistance Patterns and Molecular Characterization of Klebsiella pneumoniae in Clinical Isolates at Mbarara Regional Referral Hospital
(Advances in Infectious Diseases, 2019-08)Background: Klebsiella pneumoniae is one of the most frequent opportunistic pathogens causing a range of infections and being resistant for beta- lactamases (ESBL) and Carbapenemases. Aim: The aim of the present study ... -
Antimicrobial resistance profile among bacteria isolated from patients presenting with wounds at Kabale Regional Referral Hospital, South western Uganda
(Research square, 2020)Background: Bacterial Wound infection and antimicrobial resistance remains a public health challenge. The challenge remains worse due to nosocomial bacterial infection often characterized by multidrug resistance. Infected ... -
Assessing the knowledge, training and capacity of health workers in the diagnosis and management of soil-transmitted helminths and schistosomiasis in eastern Uganda
(Transactions of The Royal Society of Tropical Medicine and Hygiene, 2024)Background: Neglected tropical diseases (NTDs) affect millions of people in Africa, with Uganda bearing a significant burden. The World Health Organization (WHO) set a goal to reduce NTDs and improve access to diagnosis and ... -
Assessing the quality of drinking water from selected water sources in Mbarara city, Southwestern Uganda
(PLoS ONE, 2024)This study assessed the physical, chemical, and microbiological quality with emphasis on risk score, source apportionment, geochemistry, feacal coliforms and water quality index of drinking water from selected water sources. ... -
Assessment of Pathogenic Contamination and Antimicrobial Activity of Selected Herbal Medicinal Remedies in Mbarara City, South Western Uganda
(Research square, 2021)Background: Herbal formulations in Mbarara have been used in the treatment and management of several disease conditions extensively overtime due to low cost compared to empirical synthetic medicine, however evidenced that ... -
Bacterial Contamination of Blood and Blood Products at Mbarara Regional Blood Bank in Rural South Western Uganda
(Advances in Infectious Diseases, 2013-09)Background: Screening blood donors has practically eliminated viral and bacterial pathogens in blood used for trans- fusion. However, transfusion-associated bacterial sepsis remains an important health-care concern and the ... -
Bacteriological profile, antibiotic susceptibility and factors associated with neonatal Septicaemia at Kilembe mines hospital, Kasese District Western Uganda
(BMC microbiology, 2021)Introduction: Neonatal septicaemia is one of the most common leading causes of neonatal morbidity and mortality in developing countries. It is estimated to affect more than 30 million people worldwide annually, potentially ... -
Carbapenem‑resistant Enterobacteriaceae in the livestock, humans and environmental samples around the globe: a systematic review and meta‑analysis
(Scientific Reports, 2024)Carbapenem‑resistant Enterobacteriaceae (CRE) have diminished treatment options causing serious morbidities and mortalities. This systematic review and meta‑analysis assessed the prevalence and associated factors of ... -
Characterization of Antibiotic Resistance in Select Tertiary Hospitals in Uganda: An Evaluation of 2020 to 2023 Routine Surveillance Data
(Tropical Medicine and Infectious Disease, 2024)Antimicrobial resistance (AMR) is a public health concern in Uganda. We sought to conduct an extended profiling of AMR burden at selected Ugandan tertiary hospitals. We analyzed routine surveillance data collected between ... -
Characterization of Extended Spectrum Beta-lactamase Uropathogens Isolated from Refugees with Urinary Tract Infections in Nakivale Refugee Settlement Camp, Southwestern Uganda
(International STD Research & Reviews, 2024)The World Health Organization estimates one in four individuals has had at least one urinary tract infection (UTI) episode requiring treatment with an antimicrobial agent. At Nakivale refugee camp, the overwhelming number ... -
Chromatographic, Mass and Cytotoxicity analysis of Isolates from Eichhornia crassipes’ Roots and Leaves against HepG2 and MCF7 cell lines
(Cogent Biology, 2021-01-29)Cancers remain one of the leading causes of death in the world. However, known conventional cancer medicines remain scarce, expensive and out of reach to many patients. To provide an alternative for the expensive therapies, ... -
Clindamycin Resistance among Methicillin Resistant Staphylococcus aureus Isolated from Human and Respective Household Swine in Greater Kabale Region—South Western Uganda
(Advances in Infectious Diseases, 2019-12-12)Introduction: S. aureus is recognized as the common cause of nosocomial and community-acquired infections. Macrolide-Lincosamide-Streptogramin B (MLSB) is thought to be alternative therapies against MRSA infections. ... -
Clindamycin Resistance among Staphylococcus Aureus Isolated at Mbarara Regional Referral Hospital, in South Western Uganda
(2014-12)Aims—The study was conducted to determine the prevalence of Clindamycin (CL) resistance and antimicrobial susceptibility among clinical isolates of Staphylococcus aureus (S. aureus) from Mbarara Regional Referral Hospital ... -
Clinical Conditions of Hospitalized Older Adult Patients and Their Outcomes in a Regional Referral Hospital in Southwestern Uganda
(Journal of Aging Research, 2019-06-29)Background. Recent advances in medicine have caused positive impact on the life expectancy of most countries, resulting in increased older adult population. Aging comes with a number of health challenges. (is study ...