Research articles: Recent submissions
Now showing items 21-40 of 181
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An evaluation of obstetrical data collection at health institutions in Mbarara Region, Uganda and Benue State, Nigeria
(The Pan African Medical Journal, 2024)Obstetrical decision-making relies on comprehensive sources of accurate data. The breadth and completion rates of obstetrical data captured at health institutions in low-to-middle income countries (LMICs) are not well ... -
Prevalence of cervical intraepithelial lesions and associated factors among women attending a cervical cancer clinic in Western Uganda; results based on Pap smear cytology
(SAGE Open Medicine, 2024)Introduction: There are high incidence and mortality rates of cervical cancer among females in East Africa. This is exacerbated by limited up-to-date data on premalignant lesions and associated factors in this setting. In ... -
Distinct cytokine profiles in late pregnancy in Ugandan people with HIV
(Scientific Reports, 2024)During pregnancy, multiple immune regulatory mechanisms establish an immune‑tolerant environment for the allogeneic fetus, including cellular signals called cytokines that modify immune responses. However, the impact of ... -
Customization and acceptability of the WHO labor care guide to improve labor monitoring among health workers in Uganda. An iterative development, mixed method study
(PLOS Global Public Health, 2024)Cognisant of persistently high maternal and perinatal mortality rates, WHO called for adoption and evaluation of new adaptable and context-specific solutions to improve labor monitoring and health outcomes. We aimed at ... -
Association between HIV Serostatus and premalignant cervical lesions among women attending a cervical cancer screening clinic at a tertiary care facility in southwestern Uganda: a comparative cross-sectional study
(BMC Women's Health, 2024)Background: Uganda has approximately 1.2 million people aged 15–64 years living with human immunodeficiency virus (HIV). Previous studies have shown a higher prevalence of premalignant cervical lesions among HIV-positive ... -
High Rate of Loss to Follow-Up Among Patients Undergoing Treatment for Premalignant Cervical Lesions at Mbarara Regional Referral Hospital, Southwestern Uganda: A Retrospective Cohort Study
(Cureus, 2023)Background: For a cervical cancer control program to be effective in reducing the incidence of the disease, there should be high compliance to treatment and follow-up of women diagnosed with precursor lesions. Screening ... -
Labour Care Guide implementation as a decision- making tool for monitoring labour among healthcare providers in Uganda: protocol for a mixed- methods study
(BMJ Open, 2024)Introduction: The new WHO Labour Care Guide (LCG), also regarded as the ‘next- generation partograph’, is a core component of 2018 WHO consolidated guidelines on intrapartum care for positive childbirth experience. The ... -
Association between serum P16ink4A concentration and CIN and cervical cancer among women attending a cervical cancer clinic in western Uganda: A case control study
(ynecologic Oncology Reports, 2024)Introduction: Tissue expression of P16ink4A is correlated with cervical lesions. In this study we determined the association between serum P16ink4A concentrations and cervical lesions among women attending the cervical ... -
Prevalence and Risk Factors for Newborn Anemia in Southwestern Uganda: A Cross-Sectional Study
(Anemia, 2024)Introduction: The global prevalence of maternal anemia is about 42%, and in sub-Saharan Africa, the prevalence of newborn anemia ranges from 25% to 30%. Anemia in newborn babies may cause complications such as delayed brain ... -
Impact of the Mbarara University of Science and Technology residency training on increasing access to specialty care workforce
(PLOS Global Public Health, 2024)Graduate tracer studies provide an avenue for assessing the impact of residency training on the distribution and access to specialty care and exploring job and professional satisfaction of alumnus. This study examined how ... -
Knowledge, attitudes, and practices of health professions students on mentorship: a cross‑sectional study at a sub‑Saharan African medical school
(Discover Education, 2024-03-08)Background Mentoring involves the informal conveyance of knowledge, social capital, and support, as perceived by the recipient to be pertinent to aspects of work, career, and personal or professional development. Students ... -
Prevalence and Factors Associated with Hepatitis B Infection Among Outpatient Adults in South-Western Uganda
(Hepatic Medicine: Evidence and Research, 2022)Background: About 2 billion people in the world are exposed to hepatitis B virus. Africa contributes 25% of the global Hepatitis B burden and prevalence in Uganda is 4.3%. Routine testing to establish the burden, improve ... -
Induced abortion: a cross-sectional study on knowledge of and attitudes toward the new abortion law in Maputo and Quelimane cities, Mozambique
(BMC Women's Health, 2020)Background: Maternal mortality, of which 6.7% is attributable to abortion complications, remains high in Mozambique. The objective of this paper is to assess the level of induced abortion at the community, as well as to ... -
Incidence and predictors of acute kidney injury among women with severe preeclampsia at Mbarara Regional Referral Hospital
(BMC nephrology, 2022)Background: The presence of acute kidney injury (AKI) in pre-eclampsia complicates treatment including; increasing length of hospital stay and a need to access services like dialysis which are largely expensive in ... -
A practical tool for managing change: crosssectional psychometric assessment of the safe surgery organizational readiness tool
(International Journal of Surgery, 2024)Background: Strengthening health systems through planned safety and quality improvement initiatives is an imperative to achieve more equitable, resilient, and effective care. And yet, years of organizational behavior ... -
Magnitude and trends in cervical cancer at Mbarara Regional Referral Hospital in South Western Uganda: Retrospective analysis of data from 2017–2022
(PLOS Global Public Health, 2024)High-income countries have documented a significant decline in the incidence and mortality of cervical cancer over the past decade but such data from low and middle-income countries such as Uganda is limited to ascertain ... -
Serum Lipids, Insulin-Like Growth Factor Binding Protein-3 and Treatment Outcomes in Women with and without Cervical Lesions in South Western Uganda: A Cohort Study
(Pathology and Laboratory Medicine International, 2024)Purpose: There is a documented association between cervical cancer and metabolic syndrome. In this study, we determined the association between lipids, insulin-like growth factor binding protein-3 (IGFBP-3) and treatment ... -
Demand-Side Factors in Maternal Health Outcomes: Evidence from a Community Health Worker Programme in Uganda
(The Journal of Development Studies, 2023)While community health workers (CHWs) are a core feature of many low-resource healthcare systems, evidence on both their health impacts and the mechanisms behind these impacts remains limited. Using a difference-in-differences ... -
Maternal near miss as a predictor of adverse perinatal outcomes: findings from a prospective cohort study in southwestern Uganda
(BMC Pregnancy and Childbirth, 2024)Background: Despite efforts, Uganda has not met the World Health Organization target of < 12 newborn deaths per 1,000 live births. Severe maternal morbidity or ‘near miss’ is a major contributor to adverse perinatal outcomes, ... -
Impact of corona virus disease 2019 on antenatal care services in rural western Uganda; a retrospective study
(International Journal of Africa Nursing Sciences, 2023)Introduction: The Coronavirus 2019 (COVID-19) outbreak poses an important threat to public health but also unique challenges to healthcare workers. The pandemic has resulted into redirection of funds and attention by ...