Research articles: Recent submissions
Now showing items 81-100 of 181
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Prevalence and Factors Associated with Non-Adherence to Antidiabetic Medication Among Patients at Mbarara Regional Referral Hospital, Mbarara, Uganda
(Patient Preference and Adherence, 2022-02-22)Background: Non-adherence is a major concern in the treatment of diabetes mellitus and undermines the goals of treatment. The objective of this study was to determine the magnitude of non-adherence and its contributing ... -
Maternal mortality at a referral hospital in south western uganda: a 5 year descriptive analysis
(American Journal of Obstetrics & Gynecology, 2021)Objective: To determine trends in the rates and causes of maternal mortality and describe clinical features among maternal deaths at the Mbarara Regional Referral Hospital (MRRH) in South-Western, Uganda. Study design: ... -
Does screening, treatment and prevention for infectious diseases by attending 4 antenatal care visits decrease the risk of stillbirth and poor birth outcomes in rural uganda?
(American Journal of Obstetrics & Gynecology, 2017-12)OBJECTIVES: Infectious causes of stillbirth, including syphilis and malaria, are prevalent in resource-limited settings. Infection screening, treatment, and prevention are pillars of antenatal care (ANC). Data are lacking ... -
Bridging the data gap in global health: an electronic surgical outcomes database at Mbarara Regional Referral Hospital, Uganda
(The Lancet Global Health, 2018-03-15)Background: Annually, an estimated 17 million lives are lost from conditions requiring surgical care and at least 77・2 million disability-adjusted life-years could be averted through provision of basic surgical services. ... -
Prevalence, clinical presentation and factors associated with Uterine fibroids among women attending the Gynecology Outpatient Department at a large Referral Hospital in Southwestern Uganda
(East African Science, 2022)Background: Uterine fibroids are the most common benign female gynecologic tumors. There are multiple risk factors, including age and reduced fertility. There is however a paucity of data on disease burden and risk factors ... -
Minor gynecologic surgery: A review of the training experience and skill building opportunities for providers in low and middle income countries
(Open Journal of Obstetrics and Gynecology, 2014)Purpose: Minor gynecologic surgery is the cornerstone of gynecologic evaluation and intervention in countries with a well-established medical infrastructure. Surgical training and exposure to minor procedures are not ... -
Post-discharge infections and healthcare contact in ugandan women hospitalized for delivery
(American Journal of Obstetrics & Gynecology, 2017)Objectives: Postpartum infection is a common cause of pregnancy related morbidity. Data are lacking from resource-limited settings on post-discharge febrile morbidity and healthcare contact in women with in-hospital ... -
Surgical, Obstetric, and Anesthetic Mortality Measurement at a Ugandan Secondary Referral Hospital
(Anesthesia & Analgesia, 2021)Background: The health care systems of low-income countries have severely limited capacity to treat surgical diseases and conditions. There is limited information about which hospital mortality outcomes are suitable metrics ... -
Effect of early tranexamic acid administration on mortality, hysterectomy, and other morbidities in women with post-partum haemorrhage (WOMAN): an international, randomised, double-blind, placebo-controlled trial
(Lancet, 2017-04-26)Background: Post-partum haemorrhage is the leading cause of maternal death worldwide. Early administration of tranexamic acid reduces deaths due to bleeding in trauma patients. We aimed to assess the effects of early ... -
Risk factors for postpartum intrauterine device expulsion among women delivering at a tertiary Hospital in Uganda: a prospective cohort study
(Contraception and Reproductive Medicine, 2021)Background: Postpartum intrauterine device (PPIUD) use refers to intrauterine device (IUD) insertion after delivery but within 48 h of birth. In Uganda, the general use of modern methods of contraception is low with < 1% ... -
Placental decidual arteriopathy and vascular endothelial growth factor A (VEGF-A) expression among women with and without HIV
(The Journal of Infectious Diseases, 2021)Background: Women with HIV (WHIV) are at higher risk of adverse birth outcomes. Proposed mechanisms for the increased risk include placental arteriopathy (vasculopathy) and maternal vascular malperfusion (MVM) due to ... -
Implementing community-based human papillomavirus self-sampling with SMS text follow-up for cervical cancer screening in rural, southwestern Uganda
(Journal of Global Health, 2021)Background Self-collected HPV screening may improve cervical cancer screen¬ing coverage in low resource countries, yet data guiding implementation and fol¬low-up of abnormal results are sparse. Methods This is a prospective ... -
Cesarean delivery in low- and middle-income countries: A review of quality of care metrics and targets for improvement
(Seminars in Fetal and Neonatal Medicine, 2021)Improving quality of care in low-and middle-income countries (LMICs) is a global priority, specifically around maternal and newborn care, where mortality and morbidity remain unacceptably high. Cesarean delivery is the ... -
Antenatal couples’ counselling in Uganda (ACCU): study protocol for a randomised controlled feasibility trial
(Pilot and Feasibility Studies, 2022)Background: Common avoidable factors leading to maternal, perinatal and neonatal deaths include lack of birth planning (and delivery in an inappropriate place) and unmet need for contraception. Progress has been slow because ... -
Altered Maternal Antibody Profiles in Women With Human Immunodeficiency Virus Drive Changes in Transplacental Antibody Transfer
(Clinical Infectious Diseases, 2022)Background: Human immunodeficiency virus (HIV)–exposed, uninfected (HEU) children have a higher risk of severe infection, but the causes are poorly understood. Emerging data point to altered antibody transfer in women with ... -
Post-discharge infections and healthcare contact in ugandan women hospitalized for delivery
(American Journal of Obstetrics & Gynecology, 2017)Objectives: Postpartum infection is a common cause of pregnancy related morbidity. Data are lacking from resource-limited settings on post-discharge febrile morbidity and healthcare contact in women with in-hospital ... -
Maternal anemia is associated with adverse obstetric, neonatal and placental outcomes in Mbarara, Uganda
(American Journal of Obstetrics & Gynecology, 2020)Objective: Maternal anemia is a significant risk factor for maternal morbidity and mortality, affecting 42% of pregnant women globally. In addition to increased risk of death from peripartum hemorrhage, anemic pregnant ... -
HIV Infection and risk of postpartum infection, complications and mortality in rural Uganda
(AIDS Care, 2018)HIV infection may increase risk of postpartum infection and infection-related mortality. We hypothesized that postpartum infection incidence and attributable mortality in Mbarara, Uganda would be higher in HIV-infected ... -
Cesarean delivery variation across facilities in Uganda
(American Journal of Obstetrics & Gynecolog, 2021-02)Objective: To describe caesarean delivery (CD) rates and their variability across health facilities and regions in Uganda. Study design: Using the 2018-2019 Ugandan Annual Health Sector Report, we extracted data on facility ... -
Inadequate Knowledge of Neonatal Danger Signs among Recently Delivered Women in Southwestern Rural Uganda: A Community Survey
(PLOS ONE, 2014-05-13)Background: Early detection of neonatal illness is an important step towards improving newborn survival. Every year an estimated 3.07 million children die during their first month of life and about one-third of these deaths ...