Faculty of Medicine: Recent submissions
Now showing items 61-80 of 2024
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Preclinical immunomodulatory activity of COVIDEX® herbal product developed for supportive treatment of COVID-19 in Uganda
(African Journal of Pharmacy and Pharmacology, 2024)The outbreak of the COVID-19 pandemic due to the SARSCoV-2 virus caused international lockdown with devastating effects on global health. In Africa, most people resorted to the use of herbal products for the prevention and ... -
Impact of Artemisia annua and Moringa oleifera on Viral Load, T Cell Activation, and Exhaustion in Ugandan People Living with HIV/AIDS (PLWH)
(African Journal of Pharmacy and Pharmacology, 2024)Highly active antiretroviral therapy (HAART) effectively controls HIV replication in HIV-positive individuals, but chronic immune activation persists, leading to increased virus replication, T cell depletion, and exhaustion, ... -
Corrigendum to “The global burden of suicidal behavior among people experiencing food insecurity: A systematic review and meta-analysis”.
(Journal of affective disorders, 2024)The strength of the relationships: “There was a positive relationship between experiencing food insecurity and (i) suicide ideation (aOR=1.078 [95% CI: 1.075-1.082; I2=99.5%, p<0.001, k=30]), (ii) suicide plans (aOR=1.496 ... -
PD-L1 Expression and Its Association With p16 in Head and Neck Squamous Cell Carcinoma in Southwestern Uganda
(Pathology and Laboratory Medicine International, 2024)Purpose: Head and Neck squamous cell carcinoma (HNSCC) is the seventh most common cancer in the world. The prognosis of patients with HNSCC remains unsatisfactory, with a 5-years survival rate of only approximately 50%. ... -
Association between fetal hemoglobin, lactate dehydrogenase, and disease severity in patients with sickle cell disease at Bugando Medical Centre, Mwanza, Tanzania
(Plos one, 2024)Introduction: There is a wide range of clinical manifestations in sickle cell disease (SCD). Despite having the same condition, each person’s response to disease complications differs greatly. Individuals can be categorized ... -
Differences in mental illness stigma by disorder and gender: Population-based vignette randomized experiment in rural Uganda
(PLOS Mental Health, 2024)Understanding and eliminating mental illness stigma is crucial for improving population mental health. In many settings, this stigma is gendered, from the perspectives of both the stigmatized and the stigmatizers. We aimed ... -
Population Effectiveness of Dolutegravir Implementation in Uganda: A Prospective Observational Cohort Study (DISCO), 48-Week Results
(The Journal of Infectious Diseases, 2024)Background: Tenofovir/lamivudine/dolutegravir (TLD) is the preferred first-line antiretroviral therapy (ART) regimen for people with HIV (PWH), including those who were previously virologically suppressed on nonnucleoside ... -
The 2024 Pediatric Sepsis Challenge: Predicting In-Hospital Mortality in Children With Suspected Sepsis in Uganda
(Pediatric Critical Care Medicine, 2024)The aim of this “Technical Note” is to inform the pediatric critical care data research community about the “2024 Pediatric Sepsis Data Challenge.” This competition aims to facilitate the development of open-source algorithms ... -
Psychometric evaluation of the affiliate stigma scale for caregivers of people with mental illness in Uganda
(BMC psychology, 2024)Background: Affiliate stigma is common among caregivers of people with mental illness and impacts negatively on the caregivers’ quality of life and their ability to care for the patients. Although there is evidence of ... -
Prevention and management of anaemia in pregnancy: Community perceptions and facility readiness in Ghana and Uganda
(PLOS Global Public Health, 2024)Anaemia is one of the most common conditions in low- and middle-income countries, with prevalence increasing during pregnancy. The highest burden is in Sub-Saharan Africa and South Asia, where the prevalence of anaemia in ... -
Outcomes of a honey and olive oil-based dressing material on wounds of women that have had a caesarean section in south-western Uganda
(International Wound Journal, 2024)Postpartum sepsis following caesarean sections among women in Uganda remains a risk. However, erratic supplies of standard dressing material make the risk a reality. Alternative wound dressing materials, therefore, remain ... -
Impact of postpartum maternal fever or hypothermia on newborn and early infant illness and death in Southwestern Uganda
(BMC Pregnancy and Childbirth, 2024)Background: Deaths occurring during the neonatal period contribute close to half of under-five mortality rate (U5MR); over 80% of these deaths occur in low- and middle-income countries (LMICs). Poor maternal antepartum and ... -
Prevalence of and Factors Associated with Adverse Maternal Obstetrical Events Among Teenage Mothers Delivering in a Tertiary Referral Hospital in Southwestern Uganda
(Cureus, 2024)Introduction: Many female teenagers in low-resource settings conceive, of which half are unplanned and end in many deaths in sub-Saharan Africa, accounting for the majority of the cases. Teenage pregnancy is associated ... -
Clinical profiles, incidence and predictors of early neonatal mortality at Mbarara Regional Referral Hospital, south-western Uganda
(BMC pediatrics, 2024)Background: The current neonatal mortality rate in Uganda is high at 22 deaths per 1000 live births, while it had been stagnant at 27 deaths per 1000 live births in the past decade. This is still more than double the World ... -
Anticancer potential of delphinidin and its derivatives: therapeutic and mechanistic insights
(Medicinal Chemistry Research, 2024)Anthocyanins are water-soluble naturally occurring flavonoids present in fruits, flowers, leaves, and roots of fruit plants and vegetables. One of the important anthocyanidin components of red wine and berries is delphinidin ... -
Association between metabolic syndrome and cervical cancer among women in Southwestern Uganda: A case-control study
(Gynecologic Oncology Reports, 2024)Objective: To determine the association between MetS and its components with cervical cancer among women in South-western Uganda. Methods: We conducted an unmatched case-control study on470 participants in a1:2case-to-control ... -
Pathology in Southwest Uganda: Teaching, Mentoring, and Capacity Building
(Critical Values, 2016)MUST, which began 26 years ago as the second medical faculty in Uganda, hosts the Massachusetts General Hospital (MGH) Global Health Collaborative, through which Seed Global Health volunteers come to train and work with ... -
Experiences and lessons learned from a global research administration capacity building project to support and expand HIV/AIDS research in southwestern Uganda
(Discover Health Systems, 2024)International collaborative research projects conducted at academic research institutions, including complex basic science, clinical, and translational HIV/AIDS research, require intensive communication, coordination, and ... -
Otolaryngology Training in Uganda: The Mbarara University of Science and Technology Experience
(OTO open, 2023)Sub-Saharan Africa has a high otolaryngologic disease burden exacerbated by an inadequate number of otolaryngologists. The Otolaryngology department at Mbarara University of Science & Technology in Uganda is addressing ... -
Prevalence and Factors Associated with Refractive Errors among University Students at Mbarara University of Science and Technology, Uganda
(Open Journal of Ophthalmology, 2024)Introduction: WHO estimated that uncorrected refractive errors are the leading cause of visual impairment and second leading cause of blindness globally. University students are prone to developing refractive errors due ...