Faculty of Medicine: Recent submissions
Now showing items 81-100 of 2024
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Prevalence and risk factors of chemotherapy- induced oral mucositis among adult cancer patients at the cancer unit of Mbarara Regional Referral Hospital
(Asia‐Pacific Journal of Clinical Oncology, 2024)Background: Chemotherapy is a common treatment for cancer, but it is associated with adverse drug reactions like oral mucositis. This condition destroys basal cells in the oral mucosal layer, causing inflammation and ... -
Water Treatment Practices and MisperceivedSocial Norms among WomenLiving with Young Children in Rural Uganda
(The American journal of tropical medicine and hygiene, 2024)Access to water safe for consumption is critical for health and well-being, yet substantial structural barriers often necessitate household action to make water safer. Social norms about water treatment practices are ... -
Transition to Motherhood and Lived Experiences of Teenage Mothers Delivering in Kasese and Bundibugyo Districts, Western Uganda
(Cureus, 2024)Introduction: A large number of teenagers in low-resource settings experience pregnancy, with a significant number of these cases happening in sub-Saharan Africa. Teenage pregnancy is associated with unique physical and ... -
Traditional healer support to improve HIV viral suppression in rural Uganda (Omuyambi): study protocol for a cluster randomized hybrid effectiveness-implementation trial
(Trials, 2024)Background: Rural African people living with HIV face significant challenges in entering and remaining in HIV care. In rural Uganda, for example, there is a threefold higher prevalence of HIV compared to the national average ... -
The feasibility, appropriateness, and usability of mobile neuro clinics in addressing the neurosurgical and neurological demand in Uganda
(Plos one, 2024)Introduction: Uganda has a high demand for neurosurgical and neurological care. 78% of the over 50 million population reside in rural and remote communities where access to neurosurgical and neurological services is lacking. ... -
The epidemiology and risk factors for postnatal complications among postpartum women and newborns in southwestern Uganda: A prospective cohort study
(PLOS Global Public Health, 2024)Sub-Saharan Africa accounts for two-thirds of the global burden of maternal and newborn deaths. Adverse outcomes among postpartum women and newborns occurring in the first six weeks of life are often related, though data ... -
The diagnostic accuracy of serum and plasma microRNAs in detection of cervical intraepithelial neoplasia and cervical cancer: A systematic review and meta-analysis
(Gynecologic Oncology Reports, 2024)Studies suggest a need for new diagnostic approaches for cervical cancer including microRNA technology. In this review, we assessed the diagnostic accuracy of microRNAs in detecting cervical cancer and Cervical Intraepithelial ... -
Role of microRNAs in skin aging and its potential therapeutic interventions
(Aging Pathobiology and Therapeutics, 2024)The skin, the largest and most important organ of the body, serves diverse functions such as protection from the outside, temperature regulation, etc. It is composed of 3 layers: hypodermis, dermis, and epidermis. As the ... -
Antimicrobial Bioactivity and GC-MS Analysis of Different Extracts of Corchorus olitorius L Leaves
(e Scientific World Journal, 2022-09-20)Plants have been used for the treatment of infectious diseases among various communities worldwide with undeniable success. Corchorus olitorius L is used to treat various ailments including infections. However, there are ... -
Neurochemistry and Pharmacology of Addictions: An African Perspective
(2019)Neurochemistry deals with the chemistry of nervous system molecules such as neurotransmitters, autacoids, hormones and neuropeptides that direct functions of neurons. These chemicals modulate the central and peripheral ... -
Comparison of Antibacterial Activities of Fermented with those of Unfermented Annona muricata (L) Fruit Extracts
(International Journal for Microbiology and Applied sciences, 2015)Fermentation is known to enhance antibacterial activities of some plant products. The research aimed to compare the antibacterial activities of the fermented with those of unfermented fruits of Annona muricata, obtained ... -
Structural and In Silico Characterization of Small Molecules Isolated from Eichhornia crassipes
(Evidence-Based Complementary and Alternative Medicine, 2020)Eichhornia crassipes has been reported to have various medicinal properties including anticancer activities. The plant was collected from the Shire river in Malawi, and two cytotoxic compounds, benzene-1,4-diol and nonanedioic ... -
Combination Activity of Standard Antituberculosis Drugs and Extracts of Medicinal Plants Commonly Used in Traditional Treatment of Tuberculosis in Uganda
(Advances in Infectious Diseases, 2024)Introduction: Resistance to antituberculosis drugs and adverse drug reactions remain the leading causes of tuberculosis therapeutic failure globally. Despite the increasing acceptance of medicinal plant use in combination ... -
Providers and women’s perspectives on opportunities, challenges and recommendations to improve cervical cancer screening in women living with HIV at Mbarara Regional Referral Hospital: a qualitative study
(BMC Women's Health, 2024)Background: Cervical cancer screening uptake remains low despite being a critical prevention method for adult women living with HIV(WLHIV). These women experience greater incidence and persistence of high-risk human ... -
Psychological distress among healthcare professionals in Mbarara, following the 2022 Ebola Virus Disease outbreak in Uganda: a mixed methods study
(BMC psychiatry, 2024)Background: The 2022 Ebola Virus Disease (EVD) outbreak occurred at a time when Uganda was still battling the social and psychological challenges of the COVID-19 pandemic; placing health care professionals (HCPs) at a much ... -
Mid–Upper Arm Circumference Is a Strong Predictor of Mortality Among Ugandan Adults With HIV-Associated Cryptococcal Meningitis: A Prospective Cohort Study
(Open Forum Infectious Diseases, 2024)Background: Mortality among adults diagnosed with HIV-associated cryptococcal meningitis remains high (24%–40%). We hypothesized that nutritional state, as measured by mid–upper arm circumference (MUAC), is a potentially ... -
Maternal HIV infection drives altered placental Mtb-specific antibody transfer
(Frontiers in Microbiology, 2023)Introduction: Placental transfer of maternal antibodies is essential for neonatal immunity over the first months of life. In the setting of maternal HIV infection, HIV-exposed uninfected (HEU) infants are at higher risk ... -
Level of Satisfaction with the Learning Environment and Transition to Employment among Health Professions Graduates at a Ugandan Medical School
(Advances in Public Health, 2024)Background: To ensure training quality, medical training institutions must provide an adequate learning environment and prepare trainees for work but there is research paucity on the subject. We determined the level of ... -
Late Stage at Diagnosis of Cervical Cancer and Its Correlates at a Large Regional Referral Hospital in Uganda: A Cross-Sectional Study
(Cureus, 2024)Background: The stage of disease at diagnosis is one of the major determinants of survival in women with cervical cancer. Most women with cervical cancer in low- and middle-income countries (LMICs) present to hospitals ... -
The Impact on Public Health and Economy Using Lockdown as a Tool against COVID-19 Pandemic in Africa: A Perspective
(Journal of Epidemiology and Public Health Reviews, 2020)Background: Since the spread of Corona Virus Disease 19 (COVID-19) most African countries have embarked on a system of either total or partial lockdown and have used it as a tool for curbing the spread of COVID-19. This ...