Browsing Department of Ophthalmology by Author "Arunga, Simon"

Now showing items 1-20 of 30

    • Bilateral Candida keratitis in an HIV patient with asymptomatic genitourinary candidiasis in Uganda 

      Arunga, Simon; Kwaga, Teddy; Leck, Astrid; Hu, Victor H.; Burton, Matthew J. (Medical Mycology Case Reports, 2018-07-17)
      A 35-year-old male presented with Candida keratitis in the left eye. He was HIV positive with a CD4 of 352 cells/ μL. The eye quickly deteriorated, despite intensive antifungal treatment and was eviscerated. Five months ...

    • Changing ophthalmic practice during the COVID-19 pandemic in Uganda 

      Kanji, Raheel Rizwan; Arunga, Simon (Community Eye Health, 2020)

    • Chlorhexidine gluconate 0.2% as a treatment for recalcitrant fungal keratitis in Uganda: a pilot study 

      Arunga, Simon; Mbarak, Tumu; Ebong, Abel; Mwesigye, James; Kuguminkiriza, Dan; Ahmed, Abeer H A Mohamed; Hoffman, Jeremy John; Leck, Astrid; Hu, Victor; Burton, Matthew (Arunga, S., Mbarak, T., Ebong, A., Mwesigye, J., Kuguminkiriza, D., Mohamed, A., ... & Burton, M. (2021). Chlorhexidine gluconate 0.2% as a treatment for recalcitrant fungal keratitis in Uganda: a pilot study. BMJ open ophthalmology, 6(1), e000698., 2021-07-05)
      Objective: Fungal keratitis is a major ophthalmic public health problem, particularly in low-income and middle-income countries. The options for treating fungal keratitis are limited. Our study aimed to describe the ...

    • Delay Along the Care Seeking Journey of Patients with Microbial Keratitis in Uganda 

      Arunga, Simon; Kintoki, Guyguy M.; Gichuhi, Stephen; Onyango, John; Newton, Rob; Leck, Astrid; Macleod, David; Hu, Victor H.; Burton, Matthew J. (Ophthalmic epidemiology, 2019)
      Purpose: To describe the care seeking journey and causes of delay among patients with Microbial Keratitis in Uganda. Methods: A prospective cohort of patients presenting with microbial keratitis at the two main eye units ...

    • Delay in accessing definitive care for patients with microbial keratitis in Nepal 

      Hoffman, Jeremy J.; Yadav, Reena; Sanyam, Sandip Das; Chaudhary, Pankaj; Roshan, Abhishek; Singh, Sanjay K.; Mishra, Sailesh K.; Arunga, Simon; Hu, Victor H.; Macleod, David; Leck, Astrid; Burton, Matthew J. (Frontiers in medicine, 2022)
      Background: The aim of this study was to describe the health-seeking journey for patients with microbial keratitis (MK) in Nepal and identify factors associated with delay. Methods: Prospective cohort study where MK ...

    • Diagnosis of Fungal Keratitis in Low-Income Countries: Evaluation of Smear Microscopy, Culture, and In Vivo Confocal Microscopy in Nepal 

      Hoffman, Jeremy J.; Yadav, Reena; Sanyam, Sandip Das; Chaudhary, Pankaj; Roshan, Abhishek; Singh, Sanjay Kumar; Arunga, Simon; Hu, Victor H.; Macleod, David; Leck, Astrid; Burton, Matthew J. (Journal of Fungi, 2022)
      Clinically diagnosing fungal keratitis (FK) is challenging; diagnosis can be assisted by investigations including in vivo confocal microscopy (IVCM), smear microscopy, and culture. The aim of this study was to estimate the ...

    • Emergency management: microbial keratitis 

      Arunga, Simon; Burton, Matthew; Arinda, Gilbert (Community eye health, 2018)

    • Epidemiology of Microbial Keratitis in Uganda: A Cohort Study 

      Arunga, Simon; Kintoki, Guyguy M.; Mwesigye, James; Ayebazibwe, Bosco; Onyango, John; Bazira, Joel; Newton, Rob; Gichuhi, Stephen; Lecka, Astrid; Macleod, David; Hua, Victor H.; Burton, Matthew J. (Ophthalmic epidemiology, 2020)
      Purpose: To describe the epidemiology of Microbial Keratitis (MK) in Uganda. Methods: We prospectively recruited patients presenting with MK at two main eye units in Southern Uganda between December 2016 and March 2018. ...

    • Experiences and Perceptions of Ophthalmic Simulation-Based Surgical Education in Sub-Saharan Africa 

      Annoh, Roxanne; Banks, Lena Morgon; Gichuhi, Stephen; Buchan, John; Makupa, William; Otiti, Juliet; Arunga, Simon; Burton, Matthew J.; Dean, William H. (. Journal of surgical education, 2021)
      BACKGROUND: Simulation-based surgical education (SBSE) can positively impact trainee surgical competence. However, a detailed qualitative study of the role of simulation in ophthalmic surgical education has not previously ...

    • Eye care where there are no ophthalmologists: the Uganda experience 

      Magyezi, Joseph; Arunga, Simon (Community Eye Health, 2020)

    • HIV and the eye 

      Gichuhi, Stephen; Arunga, Simon (Community eye health, 2020)

    • How to make fluorescein strips 

      Arinda, Gilbert; Arunga, Simon (Community Eye Health Journal, 2018)
      Fluorescein strips are an essential diagnostic tool in eye care. They are useful for performing a number of procedures, such as measuring intraocular pressure, assessing dry eye and detecting corneal abrasions. Unfortunately, ...

    • The impact of microbial keratitis on quality of life in Uganda 

      Arunga, Simon; Wiafe, Geoffrey; Habtamu, Esmael; Onyango, John; Gichuhi, Stephen; Leck, Astrid; Macleod, David; Hu, Victor; Burton, Matthew (BMJ Open Ophthalmology, 2019-12-23)
      Background: Microbial keratitis (MK) is a frequent cause of sight loss in sub-Saharan Africa. However, no studies have formally measured its impact on quality of life (QoL) in this context. Methods: As part of a nested ...

    • The impact of simulation-based trabeculectomy training on resident core surgical skill competenc 

      Annoh, Roxanne; Buchan, John; Gichuhi, Stephen; Philippin, Heiko; Arunga, Simon; Mukome, Agrippa; Admassu, Fisseha; Lewis, Karinya; Makupa, William; Otiti-Sengeri, Juliet; Kim, Min; MacLeod, David; Burton, Matthew J.; Dean, William H. (Journal of glaucoma, 2023)
      Purpose: To measure the impact of trabeculectomy surgical simulation training on core surgical skill competency in resident ophthalmologists. Methods: This is a post-hoc analysis of the GLAucoma Simulated Surgery (GLASS) ...

    • Intense Simulation-Based Surgical Education for Manual Small-Incision Cataract Surgery 

      Dean, William H.; Gichuhi, Stephen; Buchan, John C.; Makupa, William; Mukome, Agrippa; Otiti-Sengeri, Juliet; Arunga, Simon; Mukherjee, Subhashis; Kim, Min J.; Harrison-Williams, Lloyd; MacLeod, David; Cook, Colin; Burton, Matthew J. (JAMA Ophthalmology, 2020-11-05)
      Importance: Cataracts account for 40% of cases of blindness globally, with surgery the only treatment. Objective: To determine whether adding simulation-based cataract surgical training to conventional training results ...

    • The Lancet Global Health Commission on Global Eye Health: vision beyond 2020 

      Burton, Matthew J; Ramke, Jacqueline; Marques, Ana Patricia; Bourne, Rupert R A; Congdon, Nathan; Arunga, Simon (The Lancet Global Health Commission, 2021)
      Eye health and vision have widespread and profound implications for many aspects of life, health, sustainable development, and the economy. Yet nowadays, many people, families, and populations continue to suffer the ...

    • Local Ugandan Production of Stable 0.2% Chlorhexidine Eye Drops 

      Picken, Christina A. R.; Brocchini, Steve; Burton, Matthew J.; Blundell-Hunter, George; Kuguminkiriza, Dan; Kaur, Harparkash; Hoffman, Jeremy J.; Arunga, Simon; Mohamed-Ahmed, Abeer H. A. (Translational Vision Science & Technology, 2023)
      Purpose: The purpose of this study was to develop a protocol to prepare buffered chlorhexidine (CHX) eye drops (0.2% w/v) in the United Kingdom that can be reproduced at a production facility in Uganda. Buffered CHX eye ...

    • Management of Filamentous Fungal Keratitis: A Pragmatic Approach 

      Hoffman, Jeremy J.; Arunga, Simon; Ahmed, Abeer H. A. Mohamed; Hu, Victor H.; Burton, Matthew J. (Journal of Fungi, 2022)
      Filamentous fungal infections of the cornea known as filamentous fungal keratitis (FK) are challenging to treat. Topical natamycin 5% is usually first-line treatment following the results of several landmark clinical trials. ...

    • The management of microbial keratitis within Uganda’s primary health system: a situational analysis [version 1; peer review: 3 approved] 

      Arunga, Simon; Kyomugasho, Naome; Kwaga, Teddy; Onyango, John; Leck, Astrid; Macleod, David; Hu, Victor; Burton, Matthew (Wellcome Open Research, 2019-09-24)
      Background: Microbial keratitis (MK) frequently leads to sight-loss, especially when the infection is severe and/or appropriate treatment is delayed. The primary health system as an entry point plays a central role in ...

    • Microbial Keratitis in Nepal: Predicting the Microbial Aetiology from Clinical Features 

      Hoffman, Jeremy J.; Yadav, Reena; Sanyam, Sandip Das; Chaudhary, Pankaj; Roshan, Abhishek; Sing, Sanjay Kumar; Arunga, Simon; Hu, Victor H.; Macleod, David; Leck, Astrid; Burton, Matthew J. (Journal of Fungi, 2022)
      Fungal corneal infection (keratitis) is a common clinical problem in South Asia. However, it is often challenging to distinguish this from other aetiologies, such as bacteria or acanthamoeba. In this prospective study, we ...