Faculty of Medicine
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The benefits of care: treated HIV infection and health-related quality of life among older-aged people in Uganda
(Aging & Mental Health, 2023)Objectives: The objective of this study is to explore how HIV care affects health-related quality of life (HRQoL) among older people in Uganda. Methods: We enrolled older-aged (≥49 years) people with HIV receiving HIV ... -
Poor Seizure Control Among Children Attending a Tertiary 8 Hospital in South Western Uganda – A Retrospective Study [Response to Letter]
(International Journal of General Medicine, 2023)The authors thank Selvi A. Mangundap for the keen interest in our study. The author notes that data obtained using medical records, it is difficult for researchers to determine matters related to the seizure onset, nature, ... -
Determinants of health-related quality of life in people with Human Immunodeficiency Virus, failing first-line treatment in Africa
(Health and Quality of Life Outcomes, 2023)Background: Antiretroviral treatment improves health related quality of life (HRQoL) of people with human immunodeficiency virus (PWH). However, one third initiating first-line treatment experience virological failure and ... -
Patient’s Perceptions of Anti-Cancer Chemotherapy Side Effects and Adherence on Treatment at Mbarara Regional Referral Hospital
(Student's Journal of Health Research Africa, 2023)Background: Chemotherapy is one of the most common treatment modalities for cancer. However, despite the benefits of indicated chemotherapy, the side effects and toxicities of the treatment frequently affect the patient’s ... -
Outcomes and Their Predictors in Post- Intensive Care Patients Admitted With Traumatic Brain Injury at Mbarara Regional Referral Hospital, Southwestern Uganda: A Retrospective Study
(Journal of Health, Medicine and Nursing, 2023)Purpose: Traumatic brain injury (TBI) is a leading cause of morbidity and mortality worldwide. TBIs are increasing in Uganda, but little is known about outcomes and their predictors in post-ICU patients. This study assessed ... -
The opioid crisis fuelled by health systems: how will future physicians fare?
(BJPsych International, 2023)The opioid crisis continues to affect many areas worldwide, raising questions regarding prescribing indications. There is no consensus on negotiating the need for pain relief and the potential for medically prescribed ... -
Physico-Chemical and Microbiological Safety of Water Utilized in the Medical Cell, Mbarara City, Southwestern Uganda, a Cross-Sectional Study
(Student's Journal of Health Research Africa, 2023)Introduction: Safe and readily available water is very vital for public health functions whether it is used for drink- ing, food production, washings, or recreation purposes. This study assessed the physical properties ... -
Outcomes of WHO defined severe respiratory distress without shock in adults in sub- Saharan Africa
(American Journal of Respiratory and Critical Care Medicine, 2023)Sepsis is the leading cause of global mortality, and is most often attributed to lower respiratory tract infections and subsequent acute respiratory distress syndrome (ARDS) (1). The greatest burden of sepsis rests on ... -
Implementation of Hepatitis B Screening Into Routine Antenatal Care to Prevent Mother-to-Child Transmission in Rural Western Uganda
(In Open Forum Infectious Diseases, 2023)In rural Uganda where birth dose vaccination for hepatitis B is not routine, we implemented a pilot program for preventing mother-to-child transmission that effectively identified women with high-risk hepatitis B virus ... -
Health System Responsiveness for Persons with HIV and Disability in South Western Uganda
(HIV/AIDS-Research and Palliative Care, 2023)Background: Inequitable access to Human Immunodeficiency Virus/Acquired Immune Syndrome (HIV/AIDS) Treatment and Care Services (HATCS) for People with Disabilities (PWD) is a hurdle to ending the pandemic by 2030. The aim ... -
Four-Month High-Dose Rifampicin Regimens for Pulmonary Tuberculosis
(NEJM Evidence, 2023)Background: Shorter but effective tuberculosis treatment regimens would be of value to the tuberculosis treatment community. High-dose rifampicin has been associated with more rapid and secure lung sterilization and may ... -
Depression in Ugandan caregivers of cancer patients: The role of coping strategies and social support
(Psycho‐Oncology, 2023)Background: Palliative care services involve the psychological care of the caregivers of cancer patients. Psychological conditions, especially depression among caregivers, distort caregiving roles; thus, it can increase a ... -
Enablers and Barriers to Hand Hygiene among Health Workers at Mbarara Regional Referral Hospital
(Journal of Health, Medicine and Nursing, 2023)Purpose: Hospital acquired infections (HAIs) are a public health problem that is more prevalent in developing countries than in developed countries. Hand hygiene is a prime preventive measure for HAIs. This study assessed ... -
Development and Validation of the Soweto Coping Scale: A Mixed-Methods, Population-Based Study of Adults Living in Soweto, South Africa
(Journal of Affective Disorders, 2022)Mental health disorders are among the leading contributors to the burden of disease and need to be prioritised in policy making and program implementation. In the absence of mental healthcare, people often navigate their ... -
Association between HIV and Prevalent Hypertension and Diabetes Mellitus in South Africa: analysis of a nationally representative cross-sectional survey
(International Journal of Infectious Diseases, 2022)Objectives: Cardiovascular diseases (CVD) burden is rising among persons living with HIV (PLWH) in sub-Saharan Africa. It is unclear whether this reflects absolute increase in HIV-related CVD risk or unmasking by improved ... -
Linkage to HIV Care Following HIV Self‑testing Among Men: Systematic Review of Quantitative and Qualitative Studies from Six Countries in Sub‑Saharan Africa
(AIDS and Behavior, 2023)Gender disparities are pervasive throughout the HIV care continuum in sub-Saharan Africa, with men testing, receiving treatment, and achieving viral suppression at lower rates, and experiencing mortality at higher rates, ... -
Prevalence of dementia and its association with central nervous system infections among older persons in northern Uganda: crosssectional community-based study
(BMC geriatrics, 2023-09)Background: Dementia is a condition in which there is deterioration in cognitive function beyond what might be expected from the usual consequence of biological aging. Few studies have been conducted on the prevalence of ... -
The role of emergency medicine interest groups in the development of emergency medicine: A case of Mbarara University of Science and Technology—Emergency Medicine Interest Group (MUST-EMIG) in Uganda
(African Journal of Emergency Medicine, 2023)Introduction: Emergency medicine (EM) is a new specialty in Uganda. There is no current formal EM undergraduate curriculum. The Mbarara University of Science and Technology Emergency Medicine Interest Group (MUST-EMIG) was ... -
Suberosin Alleviates Thiazolidinedione‑Induced Cardiomyopathy in Diabetic Rats by Inhibiting Ferroptosis via Modulation of ACSL4‑LPCAT3 and PI3K‑AKT Signaling Pathways
(Cardiovascular Toxicology, 2023)Thiazolidinediones are useful antidiabetic medications. However, their use is associated with adverse side effects like edema, heart failure and bone fractures. In this study, we investigated the anti-ferroptosis effects ... -
Systematic Review of mHealth Interventions for Adolescent and Young Adult HIV Prevention and the Adolescent HIV Continuum of Care in Low to Middle Income Countries
(AIDS and Behavior, 2023)Adolescents and young adults (AYA) in low to middle income countries (LMIC) have poorer outcomes along each step in the HIV continuum of prevention and care compared to younger children or older adults. The use of mHealth ...
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