Research Articles
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Active tuberculosis disease among people living with HIV on ART whocompleted tuberculosis preventive therapy at three public hospitals in Uganda
(PloS one, 2024)Tuberculosis (TB) preventive therapy (TPT) reduces the incidence of TB among people living with the human immunodeficiency virus (PLHIV). However, despite an increase in TPT uptake, TB/HIV coinfection remains stagnant in ... -
Antibiotic resistance of E. coli isolates from different water sources in Mbarara, Uganda
(Journal of Water and Health, 2024)Escherichia coli is widely used as an indicator of recent faecal pollution of water. Most E. coli strains are commensals; however, isolates in water samples have been shown to carry antibiotic resistance determinants. In ... -
Incidence of Acute Kidney Injury and Associated Mortality among Individuals with Drug-Susceptible Tuberculosis in Uganda
(Kidney360, 2024)Background: Although tuberculosis (TB) is associated with significant mortality and morbidity, its impact on kidney function is not well understood and is often attributed to anti-TB drugs. We aimed to assess the incidence ... -
Utilisation of ChatGPT and other Artificial Intelligence tools among medical faculty in Uganda: a cross-sectional study
(MedEdPublish, 2024)Background: ChatGPT is an open-source large language model that uses deep learning techniques to generate human-like texts. ChatGPT has the potential to revolutionize medical education as it acts as an interactive virtual ... -
Performance and acceptability of the STREAM Disinfectant Generator for infection prevention and control practices in primary health care facilities in Uganda
(Antimicrobial Resistance & Infection Control, 2024)Background: Effective infection prevention and control programs can positively influence quality of care, increase patient safety, and protect health care providers. Chlorine, a widely used and effective chemical disinfectant, ... -
Adverse events associated with AstraZeneca COVID-19 vaccine among adults in Greater Kampala, Uganda: a cross-sectional study
(African Health Sciences, 2024)Background: Uganda started AstraZeneca COVID-19 vaccination in March 2021 but information about adverse events is limited. We assessed adverse events following AstraZeneca vaccination among adults in Greater Kampala, Uganda. ... -
Effect of missed clinic visits on treatment outcomes among people with tuberculosis: a quasi-experimental study utilizing instrumental variable analysis
(IJID Regions, 2024)Objectives: Missed clinic visits disrupt the continuity of care and potentially impact tuberculosis (TB) treatment outcomes negatively. We evaluated the effect of missed clinic visits on mortality and treatment success among ... -
Effectiveness and durability of insecticide mixtures for pyrethroid resistance in sub-Saharan Africa
(The Lancet Infectious Diseases, 2024)Pyrethroid (PY) resistance is now rampant in most malaria-endemic countries, threatening to lower the effectiveness of standard long-lasting insecticide nets (LLINs) treated with PY only. Of the 88 countries that reported ... -
Joint regression modeling of blood pressure and associated factors among adults in Uganda: Implications for clinical practice
(PLOS Global Public Health, 2024)Blood pressure (BP) is a repeated measurement data as multiple measurements of both systolic blood pressure (SBP) and diastolic blood pressure (DBP) are simultaneously obtained on a patient to determine a raised blood ... -
Visa Relaxation Policies and Potential Implications on Public Health in Africa
(Journal of Travel Medicine, 2024)In November 2023, Rwanda adopted visa-free travel for all Africans. Kenya also began visa-free entry in January 2024. Between 2016 and 2023, the landscape of international travel in Africa remarkably changed due to policy ... -
Correlates of Sleep Health among Older-Age People with and without HIV in Uganda
(AIDS and Behavior, 2024)There is a growing population of older people with HIV (PWH) in Uganda. Sleep problems disproportionately affect older people and PWH. This study aimed to estimate correlates of sleep health among older Ugandans (aged ≥ ... -
Quality of care and post-discharge morbidity among children diagnosed with severe malaria in rural Uganda: A prospective cohort study
(PLOS Glob Public Health, 2024)Pediatric severe malaria is a significant contributor of morbidity and mortality in Uganda. Most information is derived from tertiary referral centers and urban centers. Little is known about routine care or post-discharge ... -
Assessment of the readiness of health facilities in urban areas to deliver geriatric-friendly care services: a cross-sectional study in Kampala City, Uganda
(BMC geriatrics, 2024)Background: With the global rise in the elderly population, ensuring geriatric-friendly healthcare services is paramount. This study aimed to assess the current readiness of health facilities in Kampala City, Uganda, to ... -
Prescription patterns of antibiotics and associated factors among outpatients diagnosed with respiratory tract infections in Jinja city, Uganda, June 2022–May 2023
(BMC Pulmonary Medicine, 2024)Background: Most respiratory tract infections (RTIs) are viral and do not require antibiotics, yet their inappropriate prescription is common in low-income settings due to factors like inadequate diagnostic facilities. ... -
“If you find that I am HIV positive, don’t tell me”: Exploring the barriers and recommendations for HIV prevention services utilization among youth in rural southwestern Uganda
(PLOS Global Public Health, 2024)Globally, the majority of new HIV infections are recorded in Eastern and Southern Africa, with the youth being disproportionately affected. HIV prevention is the cornerstone of controlling the spread of HIV and ending this ... -
Barriers and facilitators of retention in care after cervical cancer screening: patients’ and healthcare providers’ perspectives
(BMC Women's Health, 2024)Background: Cervical cancer continues to threaten women’s health, especially in low-resource settings. Regular follow-up after screening and treatment is an effective strategy for monitoring treatment outcomes. Consequently, ... -
Malnutrition is a risk factor for tuberculosis disease among household contacts: A case-control study in Uganda
(IJID regions, 2024)Objective: Household contacts (HHCs) of persons with tuberculosis (TB) including rifampicin-resistant or multi drug-resistant TB (RR/MDR-TB) are at risk for TB infection. We investigated whether index patient-level clinical ... -
Impact of supportive supervision visits on the availability of World Health Organization infection prevention and control core components in health facilities in Southwestern Uganda
(Infection Prevention in Practice, 2024)Background: In sub-Saharan Africa, the provision of infection prevention and control (IPC) measures are often limited by resource constraints. Aim: To determine the association of supportive supervision activities with the ... -
Malnutrition and unsuccessful tuberculosis treatment among people with multi-drug resistant tuberculosis in Uganda: A retrospective analysis
(Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2024)Rationale: Multi-drug-resistant tuberculosis (MDR-TB) poses a significant public health challenge to the control and successful eradication of TB globally. Suboptimal treatment outcomes are common among persons with ... -
Evolution of Spatial Risk of Malaria Infection After a Pragmatic Chemoprevention Program in Response to Severe Flooding in Rural Western Uganda
(The Journal of Infectious Diseases, 2024)Background: Malaria epidemics result from extreme precipitation and flooding, which are increasing with global climate change. Local adaptation and mitigation strategies will be essential to prevent excess morbidity and ...
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