dc.contributor.author | Nuwagira, Edwin | |
dc.contributor.author | Yekosani, Mitala | |
dc.contributor.author | Abraham, Birungi | |
dc.contributor.author | Atwine, Raymond | |
dc.contributor.author | Caleb, Tuhumwire | |
dc.contributor.author | Baluku, Joseph Baruch | |
dc.date.accessioned | 2022-02-11T09:19:48Z | |
dc.date.available | 2022-02-11T09:19:48Z | |
dc.date.issued | 2021 | |
dc.identifier.citation | Nuwagira, E., Yekosani, M., Abraham, B., Atwine, R., Caleb, T., & Baluku, J. B. (2021). Drug-Resistant Tuberculosis Presenting as a Testicular Mass: A Case Report. International medical case reports journal, 14, 145. | en_US |
dc.identifier.uri | http://ir.must.ac.ug/xmlui/handle/123456789/1463 | |
dc.description.abstract | Anti-microbial resistance is a growing threat to the effective treatment of various pathogens.1 In particular, drug-resistant tuberculosis (DR-TB) is the leading contributor to antimicrobial resistance-related death globally, with only a 55% treatment success rate reported globally.2 The global prevalence of multidrug-resistant tuberculosis (MDR-TB) continues to rise and is of public health concern. In 2019 alone, there were about half a million new cases of rifampicin-resistant tuberculosis (RR-TB), of which about 80% had MDR-TB.3
Extrapulmonary tuberculosis (EPTB), which is tuberculosis outside the lung parenchyma, constitutes 10–15% of all tuberculosis cases among HIV-negative adults and 60% in HIV-infected.4 Extrapulmonary drug-resistant tuberculosis is extremely rare and constitutes 5% of DR-TB.5 This is attributed to the low numbers of Mycobacterium tuberculosis present in the tissue and the inadequate diagnostics, especially in limited-resource settings.6 Genitourinary tuberculosis is one of the late manifestations of what was initially pulmonary tuberculosis infection. While cases of testicular and scrotal DR-TB have been described before, they are extremely rare, and there is no consensus on the appropriate management. One hospital-based cross-sectional in Uganda showed that approximately 10% (7 out of 73) of the patients presenting with testicular pain had tuberculous epididymo-orchitis.7 Here, we describe a case of a middle-aged HIV seronegative male with testicular RR-TB, who had no evidence of pulmonary involvement. | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | International Medical Case Reports Journal | en_US |
dc.subject | Drug-resistant tuberculosis | en_US |
dc.subject | Genitourinary tuberculosis | en_US |
dc.subject | Extrapulmonary tuberculosis | en_US |
dc.subject | Tuberculous orchitis | en_US |
dc.subject | Sub-Saharan Africa | en_US |
dc.subject | Uganda | en_US |
dc.title | Drug-Resistant Tuberculosis Presenting as a Testicular Mass: A Case Report | en_US |
dc.type | Article | en_US |