dc.contributor.author | Odongo, Leo | |
dc.contributor.author | Mulyowa, Grace | |
dc.contributor.author | Goebeler, Matthias | |
dc.contributor.author | Trautmann, Axel | |
dc.date.accessioned | 2022-04-09T10:41:38Z | |
dc.date.available | 2022-04-09T10:41:38Z | |
dc.date.issued | 2015 | |
dc.identifier.citation | Odongo, L., Mulyowa, G., Goebeler, M., & Trautmann, A. (2015). Bet v 1-and Bet v 2-Associated Plant Food Sensitization in Uganda and Germany: differences and similarities. International Archives of Allergy and Immunology, 167(4), 264-269. | en_US |
dc.identifier.uri | http://ir.must.ac.ug/xmlui/handle/123456789/1734 | |
dc.description.abstract | Abstract
Background: Birch pollen allergy and concomitant plant food sensitization are well documented in Europe. However, there are currently no data available on pollen-associated plant food sensitization or even pollen allergy in tropical Af rica. Our study aimed to investigate Bet v 1- and Bet v 2-as sociated plant food sensitization in atopic patients from Uganda and compare it with sensitization rates in German patients. Methods: Sera from 83 Ugandan and 97 German atopic patients were analysed using UniCAP100 TM for aller gen-specific IgE against the birch tree pollen allergens Bet v 1 and Bet v 2 as well as the plant foods hazelnut, apple, kiwi, pea, peach, cherry, litchi, peanut, and soy. Results: As ex pected, sensitization to Bet v 1 and cross-reactive plant food allergens was more common in German atopic patients. In contrast, the prevalence of sensitization against Bet v 2 was remarkably similar in Ugandan and German patients. Inter estingly, in Ugandan patients we found IgE-mediated sensitization against plant foods such as hazelnut, pea, peach, cherry, and litchi that are neither cultivated nor consumed in
Uganda. Conclusions: For Ugandan atopic patients, sensitization against the Bet v 2 allergen (a plant profilin) may explain cross-reactivity to several plant foods which are not consumed in Uganda. Additionally, it is probable that sensitization of Ugandan atopics to alder pollen ( Alnus acuminata , plant family Betulaceae) caused serological cross-reactivity with Betula verrucosa -related allergens. | en_US |
dc.description.sponsorship | German Academic Exchange Service (Deutscher Akademischer Austausch dienst, DAAD) | en_US |
dc.language.iso | en_US | en_US |
dc.publisher | Int Arch Allergy Immunology | en_US |
dc.subject | Africa | en_US |
dc.subject | Alder pollen | en_US |
dc.subject | Atopy | en_US |
dc.subject | Birch pollen | en_US |
dc.subject | Food allergy | en_US |
dc.title | Bet v 1- and Bet v 2-Associated Plant Food Sensitization in Uganda and Germany: Differences and Similarities | en_US |
dc.type | Article | en_US |