Research articles
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The Neuroprotective Efficiency of Cysteinyl Leukotriene Receptor Antagonist (Montelukast) in TBI; A Systematic Review and Meta-Analysis Protocol
(Annals of Surgery Protocols, 2024)Background: Traumatic Brain Injury (TBI) is one of the leading causes of morbidity, disability, and mortality across all ages, with a global annual incidence between 27 to 69 million. The pathophysiology of TBI involves ... -
Perceived Public Participation and Health Delivery in Local Government Districts in Uganda
(International Journal of Environmental Research and Public Health, 2024)Citizen participation is a crucial aspect of the national health system, empowering individuals to contribute to improving local health services through Health Committees (HCs). HCs promote the participation of citizens ... -
The feasibility, appropriateness, and usability of mobile neuro clinics in addressing the neurosurgical and neurological demand in Uganda
(Plos one, 2024)Introduction: Uganda has a high demand for neurosurgical and neurological care. 78% of the over 50 million population reside in rural and remote communities where access to neurosurgical and neurological services is lacking. ... -
Models to predict expansive intracranial hematomas occurrence for adult traumatic brain injury patients presenting at Accident and Emergency Department at Mulago National referral Hospital in Uganda
(Journal of Global Neurosurgery, 2024)Background: A timely and accurate surgical decision regarding expansive intracranial hematomas (EIH) is crucial in clinical practice and patient outcomes, particularly in resource-limited settings. Although several predictive ... -
Association between clinical and sonographic patterns of major peripheral arterial occlusion among patients presenting with lower limb dry gangrene at a single center in Western Uganda
(Tungs' Medical Journal, 2024-05-13)Background: Dry gangrene occurs due to a reduced blood supply in body parts, resulting in gradual necrosis. It is among the leading indications for lower limb amputation; however, in situations where timely access of ... -
Surgical Management of a Thalamic Arteriovenous Malformation in a Young Male in a Low Resource Setting: An Illustrative Case Repor
(Journal of Surgery & Anesthesia Research, 2024)Introduction: The natural history of patients with arteriovenous malformations (AVMs) suggests that 10-17% die due to hemorrhage and 40-50% experience serious physical deterioration of their working capacity in their ... -
The Impact of the Gut Microbiome, Environment, and Diet in Early-Onset Colorectal Cancer Development
(Cancers, 2024)Traditionally considered a disease common in the older population, colorectal cancer is increasing in incidence among younger demographics. Evidence suggests that population land generational-level shifts in the composition ... -
Diabetic Foot Ulcers: Surgical Characteristics, Treatment Modalities and Short-Term Treatment Outcomes at a Tertiary Hospital in South-Western Uganda
(Open Access Surgery, 2022)Background: Diabetic foot ulcers (DFUs) are a prevalent and serious consequence of poorly controlled diabetes. Hospitalizations are frequent among DFU patients, and these patients are at risk of lower extremity amputations ... -
Colonisation and its aftermath: reimagining global surgery
(BMJ Global Health, 2024)Coloniality in global health manifests as systemic inequalities, not based on merit, that benefit one group at the expense of another. Global surgery seeks to advance equity by inserting surgery into the global health ... -
CNS Cryptococcoma in an Immunocompetent Adult from a Low Resource Setting: An Illustrative Case Report
(Journal of Health, Medicine and Nursing, 2023)Purpose: Cryptococcal infection in the Central Nervous System (CNS) is frequently seen in human immunodeficiency virus (HIV) patients and others with low immunity. CNS cryptococcoma in immunocompetent patients is rare. We ... -
The safety and utility of low-intensity pulsed ultrasound for effective blood–brain barrier penetration in the treatment of glioblastoma: a scoping review protocol
(Journal of Surgical Protocols and Research Methodologies, 2023)Glioblastoma(GBM) is one of the most aggressive central nervous system tumours with suboptimal treatment options and associated poor prognosis. A major impediment to Systemic treatment is the limitation of drug delivery ... -
Assessing the neuroprotective efficacy of atorvastatin in traumatic brain injury : a systematic review protocol
(Journal of Surgical Protocols and Research Methodologies, 2023)Traumatic brain injury (TBI) is a significant public health threat, with an estimated 5.3million people in the United States alone living with a disability related to TBI (1). The most common therapies for individuals with ... -
Estimating cancer incidence in Uganda: a feasibility study for periodic cancer surveillance research in resource limited settings
(BMC cancer, 2023)Background Population based cancer registries (PBCRs) are accepted as the gold standard for estimating cancer incidence in any population. However, only 15% of the world’s population is covered by high quality cancer ... -
Prevalence, correlates and treatment needs of dental caries in patients attending a diabetic clinic in rural southwestern Uganda: a cross-sectional study
(BMC Oral Health, 2023)Background: Diabetes mellitus is a complex heterogeneous metabolic disorder known to lead to several pathogenic disorders, and has a bidirectional relationship with oral health conditions. This study aimed at estimating ... -
Quality of Life of Children After Completion of Surgical Treatment for Anorectal Malformation: A Single-Centre Cross-Sectional Study in South- Western Uganda
(Research square, 2023)Background: Anorectal malformations (ARMs) range from minor abnormalities such as imperforate anus to complex forms such as cloaca, and are often associated with other anomalies and residual functional stooling problems. ... -
A giant choledochal cyst in a 17 year old female managed in a resource limited setting: A case report
(International Journal of Surgery Case Reports, 2023)Introduction and importance: Choledochal cysts are rare congenital bile duct anomalies that lead to cystic dilatations of the biliary tree. This condition is very rare in Africa. When these cysts exceed 10 cm in diameter, ... -
24 h mortality and its predictors among road traffic accident victims in a resource limited setting; a multicenter cohort study
(BMC surgery, 2023)Introduction: The incidence of road traffic accidents (RTAs) is on the rise contributing to the global burden of mortality as a major global health threat. It has been estimated that 93% of RTAs and more than 90% of the ... -
A case report of an asymptomatic necrotic Meckel's diverticulum in an inguinal hernia during elective surgery in a resource limited setting: Littre's hernia
(International Journal of Surgery Case Reports, 2023)Introduction and importance: Although the common complications of Meckel's diverticulum (MD) are well known, that these congenital intestinal outpouchings may become involved as the content of abdominal hernia sacs is not ... -
Clinical Practices Following Train-The-Trainer Trauma Course Completion in Uganda: A Parallel-Convergent Mixed-Methods Study
(World Journal of Surgery, 2023)Background: Despite the growth of trauma training courses worldwide, evidence for their impact on clinical practice in low- and middle-income countries (LMICs) is sparse. We investigated trauma practices by trained providers ... -
Otolaryngology Training in Uganda: The Mbarara University of Science and Technology Experience
(OTO Open, 2023)Sub-Saharan Africa has a high otolaryngologic disease burden exacerbated by an inadequate number of otolaryngologists. The Otolaryngology department at Mbarara University of Science & Technology in Uganda is addressing ...
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