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dc.contributor.authorKayondo, Musa
dc.contributor.authorGeissbüehler, Verena
dc.contributor.authorMigisha, Richard
dc.contributor.authorKajabwangu, Rogers
dc.contributor.authorNjagi, Joseph
dc.contributor.authorKato, Paul Kalyebara
dc.contributor.authorFajardo, Yarine
dc.contributor.authorLugobe, Henry Mark
dc.contributor.authorKaye, Dan Kabonge
dc.date.accessioned2022-07-21T06:43:23Z
dc.date.available2022-07-21T06:43:23Z
dc.date.issued2021
dc.identifier.citationKayondo, M., Geissbüehler, V., Migisha, R., Kajabwangu, R., Njagi, J., Kato, P. K., ... & Kaye, D. K. (2021). Risk factors for recurrence of pelvic organ prolapse after vaginal surgery among Ugandan women: a prospective cohort study. International Urogynecology Journal, 1-7.en_US
dc.identifier.urihttp://ir.must.ac.ug/xmlui/handle/123456789/2259
dc.description.abstractIntroduction and hypothesis: This study was aimed at determining the recurrence rate and risk factors for the recurrence of pelvic organ prolapse (POP), at 1-year post-vaginal reconstructive surgery in a resource-limited setting. Methods: We enrolled women who underwent vaginal surgery for POP at the urogynecology unit of Mbarara Regional Referral Hospital (MRRH) in southwestern Uganda between December 2018 and February 2020. The surgeries that were performed include anterior colporrhaphy for cystocele, posterior colporrhaphy for rectocele, vaginal hysterectomy with vault suspension for uterine prolapse, and cervicopexy in those with uterine prolapse where uterine-sparing surgery was desired. The women were followed up for a period of 1 year after surgery. Pelvic examinations in lithotomy position under maximumstrain were carried out to assess for recurrence using the Pelvic Organ Quantification (POP-Q) system. Recurrence was defined as a prolapse of ≥POP-Q stage II. Descriptive analyses and multivariate log binomial regression were performed to determine risk factors for recurrence. Results: Of the 140 participants enrolled, 127 (90.7%) completed the follow-up at 1 year. The recurrence rate was 25.2% (32 out of 127). Most (56.3%) of the recurrences occurred in the anterior compartment and in the same site previously operated. Women aged <60 years (RR = 2.34; 95% CI: 1.16–4.72; p = 0.018) and those who had postoperative vaginal cuff infection (RR = 2.54; 95% CI: 1.5–4.3; p = 0.001) were at risk of recurrence. Conclusion: Recurrence of POP was common. Younger women, and those with postoperative vaginal cuff infection, were more likely to experience recurrent prolapse after vaginal repair.en_US
dc.description.sponsorshipElseKroner Fresenius Foundation (grant number: 2018_HA148)en_US
dc.language.isoen_USen_US
dc.publisherInternational Urogynecology Journalen_US
dc.subjectPelvic organ prolapseen_US
dc.subjectProlapse recurrenceen_US
dc.subjectRisk factorsen_US
dc.subjectSurgeryen_US
dc.titleRisk factors for recurrence of pelvic organ prolapse after vaginal surgery among Ugandan women: a prospective cohort studyen_US
dc.typeArticleen_US


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