Faculty of Medicine: Recent submissions
Now showing items 1021-1040 of 1992
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Health‑related quality of life among patients with bipolar disorder in rural southwestern Uganda: a hospital based cross sectional study
(Health Quality Life Outcomes, 2021)Background: Bipolar disorder is a psychiatric disorder that alters mood and affects over 55 million people globally with an estimated lifetime prevalence of approximately 0.8–1.1%. In Africa, the lifetime prevalence of the ... -
Caregivers’ Attitudes towards HIV Testing and Disclosure of HIV Status to At-Risk Children in Rural Uganda
(PLoS ONE, 2016-02-16)Caregivers of HIV-positive children were interviewed in the Mbarara and Isingiro districts of Uganda to identify current trends in practices related to HIV testing and the disclosure of HIV status to the child. A total of ... -
Barriers to Uptake of Postpartum Long-Acting Reversible Contraception: Qualitative Study of the Perspectives of Ugandan HealthWorkers and Potential Clients
(Studies in family planning, 2019)Health workers have received training on delivering postpartum long-acting reversible contraceptives (LARCs) through several projects in Uganda, yet uptake still remains poor. To understand the reasons, and to gather ... -
Addressing WHO Resolution 60.22: A Pilot Project to Create Access to Acute Care Services in Uganda
(Annals of Emergency Medicine, 2014)The World Health Organization’s (WHO’s) 2007 Resolution 60.22 tasked the global health community to address the lack of emergency care in low- and middle-income countries. Little progress has yet been made in integrating ... -
HIV-1 seroprevalence and risk factors for HIV infection among first-time psychiatric admissions in Uganda
(AIDS Care, 2011-02)This study investigated HIV seroprevalence and its correlates among patients with first-time psychiatric admissions to two national referral hospitals in urban Kampala, Uganda. A structured standardised evaluation was used ... -
Pioneering work in mental health outreaches in rural, southwestern Uganda
(Intervention, 2008)In Uganda, the rates of mental illness are high due to poverty, high prevalence of HIV/AIDS and long term exposure to civil wars and armed rebellion. The cost of mental health services in urban hospitals remain prohibitive ... -
Barriers and strategies needed to improve maternal health services among pregnant adolescents in Uganda: a qualitative study
(Global Health Action, 2022)Background: In Uganda, the uptake of maternal health services is very low, with only 41.1% of pregnant adolescent girls attending the eight antenatal visits that are recommended by the World Health Organisation. Uptake ... -
Prevalence of Ethanol Use Among Pregnant Women in Southwestern Uganda
(Maternal and child health journal, 2016)Introduction: The prevalence of ethanol use in many Sub-Saharan African countries is high, but little research exists on use during pregnancy. The objective of this study was to assess the prevalence and predictors of ... -
Early empiric anti-Mycobacterium tuberculosis therapy for sepsis in sub-Saharan Africa: a protocol of a randomised clinical trial
(BMJ Open, 2022)Introduction: Sub-Saharan Africa shoulders the highest burden of global sepsis and associated mortality. In high HIV and tuberculosis (TB) prevalent settings such as sub-Saharan Africa, TB is the leading cause of sepsis. ... -
Super learner analysis of real-time electronically monitored adherence to antiretroviral therapy under constrained optimization and comparison to non-differentiated care approaches for persons living with HIV in rural Uganda
(Journal of the International AIDS Society, 2020)Introduction: Real-time electronic adherence monitoring (EAM) systems could inform on-going risk assessment for HIV viraemia and be used to personalize viral load testing schedules. We evaluated the potential of real-time ... -
Reversal of the Kynurenine Pathway of Tryptophan Catabolism May Improve Depression in ART-treated HIV-infected Ugandans
(Journal of acquired immune deficiency syndromes, 2014-04)Background: Major depressive disorder is highly prevalent among HIV-infected persons, and depression symptom severity improves during the course of HIV antiretroviral therapy (ART). The potential biologic pathways explaining ... -
Real-time electronic adherence monitoring plus follow-up improves adherence compared to standard electronic adherence monitoring
(AIDS, 2017-01)The impact of real-time electronic monitoring on antiretroviral therapy adherence warrants further study. We conducted an analysis of cohort participants that initially involved standard electronic adherence monitoring ... -
Real-time Adherence Monitoring of Antiretroviral Therapy Among HIV-infected Adults and Children in Rural Uganda
(AIDS, 2013-08)A real-time wireless electronic adherence monitor(EAM) and weekly self-report of missed doses via interactive voice response (IVR) and short message service (SMS) queries were used to measure ART adherence in 49 adults and ... -
Prevalence and Virologic Consequences of Transmitted HIV-1 Drug Resistance in Uganda
(AIDS research and human retroviruses, 2014)Few reports have examined the impact of HIV-1 transmitted drug resistance (TDR) in resource-limited settings where there are fewer regimen choices and limited pretherapy/posttherapy resistance testing. In this study, we ... -
Prevalence and Clinical Impacts of HIV-1 Intersubtype Recombinants in Uganda Revealed by Near-Full-Genome Population and Deep Sequencing Approaches
(Lee, G. Q., Bangsberg, D. R., Mo, T., Lachowski, C., Brumme, C. J., Zhang, W., ... & Harrigan, P. R. (2017). Prevalence and clinical impacts of HIV-1 intersubtype recombinants in Uganda revealed by near-full-genome population and deep sequencing approaches. AIDS (London, England), 31(17), 2345., 2017)Objectives: To estimate prevalence, examine time trends, and test for clinical correlates and outcomes associated with HIV-1 intersubtype recombination under a full-genome sequencing context in a rural community in Mbarara, ... -
Pre-treatment integrase inhibitor resistance is uncommon in ART-naïve individuals with HIV-1 subtype A1 and D infections in Uganda
(AIDS, 2020)Objective: Dolutegravir (DTG) is now a preferred component of first-line antiretroviral therapy (ART). However, prevalence data on natural resistance to integrase inhibitors (INSTIs) in circulating non-subtype B HIV-1 in ... -
Predictors of Medication-Related Emergency Department Admissions Among Patients with Cardiovascular Diseases at Mbarara Regional Referral Hospital, South-Western Uganda
(Open Access Emergency Medicine, 2021)Background: Medication-related emergency department admissions impose a huge and unnecessary burden on the healthcare system. We sought to determine the prevalence and predictors of medication-related emergency department ... -
Positive deviance for dual-method promotion among women in Uganda: study protocol for a cluster randomized controlled trial
(Trials, 2020)Background: Dual-method use is known as the most reliable protection against unintended pregnancies and sexually transmitted infections, including HIV. However, it is not commonly used in sub-Sharan Africa, especially among ... -
Positive Deviance for Dual-Method Promotion among Women in Uganda: A Qualitative Study
(International journal of environmental research and public health, 2020-07-12)Dual-method use is the most reliable form of protection against unintended pregnancies and human immunodeficiency virus/sexually transmitted infections (HIV/STIs). Although dual-method use remains uncommon among women in ... -
Upper gastrointestinal diseases in patients for endoscopy in South-Western Uganda
(African Health Sciences, 2015)Background: There is a paucity of published data regarding upper gastrointestinal diseases in Ugandans with upper gastrointestinal symptoms referred for endoscopy. Objectives: To study the presenting complaints, pathology ...