Faculty of Medicine: Recent submissions
Now showing items 1401-1420 of 1992
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Phytochemical and Antidiabetic Evaluation of the Methanolic Stem Bark Extract of Spathodea campanulata (P. Beauv.) Bignoniaceae
(Pharmacognosy Journal, 2016-05)Background: Spathodea campanulata (P. Beauv.) Bignoniaceae extract (SCE) is one of many herbal medicines used widely in Ugandan traditional medicine for various ailments. Generally most of these herbal medicines are yet ... -
Physiological and psychosocial stressors among hemodialysis patients in the Buea Regional Hospital, Cameroon
(Pan African Medical Journal, 2018-05-18)Introduction: End Stage Renal Disease (ESRD) is an irreversible kidney condition and hemodialysis is the most frequent treatment option used for this condition. However, hemodialysis also has a detrimental impact on the ... -
Anxiety, Anger and Depression Amongst Low-Income Earners in Southwestern Uganda During the COVID-19 Total Lockdown
(Frontiers in Public Health, 2021-12)Background: Low-income earners are particularly vulnerable to mental health, consequence of the coronavirus disease 2019 (COVID-19) lockdown restrictions, due to a temporary or permanent loss of income and livelihood, ... -
Infections
(African Health Sciences, 2011-09)Background: Medicinal plants in Uganda and other developing countries have been scientifically demonstrated to have medicinal benefits but few or none have been translated to products for clinical use. Most herbal products ... -
Antisickling effect of crude flavonoids in the methanolic leaf extract of Persea americana Mill
(Revista Cubana de Plantas Medicinales, 2019-06)Introduction: Sickle-cell anemia, a difficult-to-treat genetic disease, causes synthesis of abnormal hemoglobin in which erythrocytes assume a sickle shape and become susceptible to hemolysis. Research about Persea americana ... -
Anticonvulsant and anxiolytic activity of the leaf aqueous and ethanolic extracts of Melanthera scandens in a rat model
(HHS Public Access, 2016)Modern drug therapy of epilepsy is complicated by the inability of drugs to control seizures in some patients and side effects that range in severity from minimal impairment of the central nervous system to death from ... -
Analgesic Appraisal of Bidens pilosa (Asteraceae) Leaf Extracts Used in Management of Oral Lesion Pain in HIV/AIDS Patients in Rodents
(Pharmacology & Pharmacy, 2018)Oral lesions, diarrhoea, Pneumocystis carinii pneumonia, tuberculosis and urinary tract infections are some of the opportunistic infections (OIs) which arise when the CD4 cells of the HIV/AIDS patient fall below 200 ... -
Aflatoxins metabolism, effects on epigenetic mechanisms and their role in carcinogenesis
(SciRes, 2013)Chronic consumption of aflatoxin-contaminated foods is a global problem in both developing and developed countries especially where there is poor regulation of their levels in foods. In the body, aflatoxins (AFBs) mainly ... -
An investigation into the number and nature of the urgent care consultations managed and referred by community pharmacists in South-East England
(Primary Health Care Research & Development, 2020)Background: Community pharmacies are recognised as an under-utilised, accessible resource that could support the urgent care agenda. This study aimed to provide a snapshot of the number and nature of urgent care requests ... -
An attitude survey and assessment of the feasibility, acceptability, and usability of a traumatic brain injury decision support tool in Uganda
(World Neurosurgery, 2020)Background Traumatic brain injury (TBI) prognostic models are potential solutions to severe human and technical shortages. Although numerous TBI prognostic models have been developed, none are widely used in clinical ... -
Aggregate Evaluable Organ Dysfunction Predicts In-Hospital Mortality from Sepsis in Uganda
(The American journal of tropical medicine and hygiene, 2011)We evaluated the association between severity of sepsis and in-hospital mortality in 150 patients with nonsurgical sepsis at a regional referral hospital in Uganda. In-hospital mortality occurred in 5 of 52 (9.6%) patients ... -
Aetiology and Treatment Outcome of Non-traumatic Small Bowel Perforations at Mbarara Hospital in South-Western Uganda
(COSECSA/ASEA Publication, 2012)Non-traumatic small bowel perforation (SBP) is the most common form of gastrointestinal perforation in sub-Saharan Africa. Although SBP is a surgical emergency associated with complications, information regarding its ... -
Adverse drug reaction reporting among health care workers at Mulago National Referral and Teaching hospital in Uganda
(African Health Sciences, 2015)Background: Adverse Drug Reactions (ADRs) are an important contributor to patient morbidity and hospitalisation in Uganda. Under-reporting of ADRs may increase medicine-induced morbidity and mortality among patients. This ... -
Access to Breast Cancer Diagnostic Devices in the East African Community: Moving the Needle
(Ascopubs, 2020)Globally, two million women develop breast cancer each year. Low-income countries bear a disproportionate burden as a result of systems strapped by limited resources. Inadequate access to diagnostic services is widely ... -
Abundance of megalin and Dab2 is reduced in syncytiotrophoblast during placental malaria, which may contribute to low birth weight
(Scientific Reports, 2016)Placental malaria caused by Plasmodium falciparum contributes to ~200,000 child deaths annually, mainly due to low birth weight (LBW). Parasitized erythrocyte sequestration and consequent inflammation in the placenta are ... -
A survey on deep learning in medical image reconstruction
(Elsevier B.V. on behalf of Chinese Medical Association., 2021)Medical image reconstruction aims to acquire high-quality medical images for clinical usage at minimal cost and risk to the patients. Deep learning and its applications in medical imaging, especially in image reconstruction ... -
A qualitative inquiry of access to and quality of primary healthcare in seven communities in East and West Africa (SevenCEWA): perspectives of stakeholders, healthcare providers and users
(Research Square, 2021)Background: Universal health coverage is one of the Sustainable Development Goal targets known to improve population health and reduce fi nancial burden. There is little qualitative data on access to and quality of primary ... -
A Pilot RCT Evaluating InThistoGether, an mHealth HIV Prevention Program for Ugandan Youth
(AIDS and Behavior, 2021)Despite data suggesting that older adolescence is an important period of risk for HIV acquisition in Uganda, tailored HIV prevention programming is lacking. To address this gap, we developed and tested nationally, ... -
Risk factors for postpartum intrauterine device expulsion among women delivering at a tertiary Hospital in Uganda: a prospective cohort study
(Contraception and Reproductive Medicine, 2021)Background: Postpartum intrauterine device (PPIUD) use refers to intrauterine device (IUD) insertion after delivery but within 48 h of birth. In Uganda, the general use of modern methods of contraception is low with < 1% ... -
Rifampicin and isoniazid drug resistance among patients diagnosed with pulmonary tuberculosis in southwestern Uganda
(PloS one, 2021)Multidrug-resistant tuberculosis (MDR-TB) has become a major threat to the control of tuberculosis globally. Uganda is among the countries with a relatively high prevalence of tuberculosis despite significant control ...