Faculty of Medicine: Recent submissions
Now showing items 341-360 of 1970
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Using microbiological data to improve the use of antibiotics for respiratory tract infections: A protocol for an individual patient data metaanalysi
(Plos one, 2023)Background: Resistance to antibiotics is rising and threatens future antibiotic effectiveness. ‘Antibiotic targeting’ ensures patients who may benefit from antibiotics receive them, while being safely withheld from those ... -
Cost-effectiveness of community-based household tuberculosis contact management for children in Cameroon and Uganda: a modelling analysis of a cluster-randomised trial
(he Lancet Global Health, 2023)Background: WHO recommends household contact management (HCM) including contact screening and tuberculosis preventive treatment (TPT) for eligible children. The CONTACT trial found increased TPT initiation and completion ... -
Blood pressure variability and early neurological outcomes in acute and subacute stroke in Southwestern Ugand
(eNeurologicalSci, 2023)Background: Greater blood pressure variability has detrimental effects on clinical outcome after a stroke; its effects are controversial and have not been evaluated in Sub-Saharan Africa (SSA). Methods: We conducted a ... -
Standard of care in advanced HIV disease: review of HIV treatment guidelines in six sub-Saharan African countries
(AIDS Research and Therapy, 2023)Background: The World Health Organization (WHO) recommends an evidence-based package of care to reduce mortality and morbidity among people with advanced HIV disease (AHD). Adoption of these recommendations by national ... -
Gaps in vaccine management practices during vaccination outreach sessions in rural settings in southwestern Uganda
(BMC Infectious Diseases, 2023)Background: Outreach efforts were developed to bolster people’s access to and use of immunization services in underserved populations. However, there have been multiple outbreaks of diseases like measles in Uganda, prompting ... -
Ten Steps Toward Improving In-Hospital Cardiac Arrest Quality of Care and Outcomes
(Circulation: Cardiovascular Quality and Outcomes, 2023)Improving in-hospital cardiac arrest (IHCA) quality of care for adult and pediatric patients—not simply survival—requires a comprehensive set of programs and actions. Ideally, these should be embedded in a system of care ... -
Experiences and perceptions of urine sampling for tuberculosis testing among HIV patients: a multisite qualitative descriptive study
(BMJ Open, 2023)Objectives: Evidence on the acceptability of urine- based assays for tuberculosis (TB) diagnosis among patients remains limited. We sought to describe patients’ experiences and perceptions of urine sampling for TB testing ... -
Planning for Hospital Discharge for Older Adults in Uganda: A Qualitative Study Among Healthcare Providers Using the COM-B Framework
(Journal of Multidisciplinary Healthcare, 2023)Background: Proper discharge planning enhances continuity of patient care, reduces readmissions, and ensures safe and timely transition from health facility to home-based care. The current study aimed at exploring the ... -
Factors Associated with Chronic Obstructive Pulmonary Disease: A Hospital-Based Case–Control Study
(International Journal of Chronic Obstructive Pulmonary Disease, 2023)Purpose: Chronic obstructive pulmonary disease (COPD) is a leading cause of morbidity and mortality worldwide. In this paper, we determined risk factors for COPD among patients presenting to pulmonology and medical ... -
Prevalence of gestational diabetes mellitus and associated factors among women receiving antenatal care at a tertiary hospital in South-Western Uganda
(The Pan African Medical Journal, 2023)Introduction: gestational diabetes mellitus is one of the major causes of morbidity and mortality among pregnant women worldwide. We aimed to determine the prevalence and factors associated with gestational diabetes mellitus ... -
Firearm-related suicides, homicides, and homicide-suicides involving security officers in two East African Countries: a press media revie
(BMC psychiatry, 2023)Background: Firearm violence is a growing public health problem causing death globally. With easy accessibility to firearms, suicides, homicides, and homicide-suicides have increased among security officers, especially in ... -
Validating the Edinburgh Postnatal Depression Scale Against the Diagnostic and Statistical Manual of Mental Disorders, 5th Edition for Use in Ugand
(International Journal of Women's Health, 2023)Background: The Edinburgh Postnatal Depression Scale (EPDS) is a widely acknowledged screening tool for postpartum depression (PPD) globally, but its validation in Uganda has been lacking. This study aimed to assess the ... -
Anemia in HIV Patients Attending Highly Active Antiretroviral Therapy Clinic at Hoima Regional Referral Hospital: Prevalence, Morphological Classification, and Associated Factor
(HIV/AIDS - Research and Palliative Care, 2023)Purpose: To determine the prevalence of anemia, the morphological classification and to assess the factors associated with anemia among HIV patients attending Highly Active Antiretroviral Therapy (HAART) clinic at Hoima ... -
Evaluation of catechin, lupeol, and betulinic acid as markers for the chromatographic quality Control of Albizia coriaria raw materials; an experimental study
(Journal of Medicinal Plants Research, 2023)Albizia coriaria stembark is among the most common raw materials used to manufacture herbal products in Uganda. While the plant material is sourced from the wild, there are neither monographs nor chemical analytical methods ... -
Higher Levels of Alcohol Use Are Associated With Latent Tuberculosis Infection in Adults Living With Human Immunodeficiency Virus
(Clinical Infectious Diseases, 2021)We assessed associations between hazardous alcohol use and latent tuberculosis infection (LTBI) among adults living with human immunodeficiency virus (HIV) in Uganda. We compared tuberculin skin test positivity across ... -
Verbal Autopsy to Assess Postdischarge Mortality in Children With Suspected Sepsis in Uganda
(Pediatrics, 2023)Background: Reducing child mortality in low-income countries is constrained by a lack of vital statistics. In the absence of such data, verbal autopsies provide an acceptable method to determining attributable causes of ... -
Evaluation of the modified colorimetric resazurin microtiter plate-based antibacterial assay for rapid and reliable tuberculosis drug susceptibility testing
(BMC microbiology, 2014)Background: The resazurin microtiter assay (classic REMA), a colorimetric liquid culture-based drug susceptibility assay for Mycobacterium tuberculosis (MTB), has been endorsed by the World Health Organization. The assay ... -
Biomarker Testing to Estimate Under-Reported Heavy Alcohol Consumption by Persons with HIV Initiating ART in Uganda
(AIDS and Behavior, 2010)Alcohol affects the transmission and treatment of HIV, yet may be under-reported in resource-limited settings. We compared self-reported alcohol consumption with levels of plasma carbohydrate-deficient transferrin (%CDT), ... -
Bacterial isolates and antibiotic susceptibility among women with abnormal vaginal discharge attending the gynecology clinic at a tertiary hospital in southwestern Uganda: a cross‑sectional study
(BMC Women’s Health, 2023)Background: Abnormal vaginal discharge is a common complaint among women of reproductive age, affecting about one- third of all women. In resource-limited settings where access to laboratory services is limited, treatment ... -
Real-time electronic adherence monitoring plus follow-up improves adherence compared with standard electronic adherence monitoring
(Aids, 2017)The impact of real-time electronic monitoring on antiretroviral therapy adherence warrants further study. We conducted an analysis of cohort participants that initially involved standard electronic adherence monitoring ...