Faculty of Medicine: Recent submissions
Now showing items 401-420 of 1973
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Effects of Maternal HIV Infection and Alcohol Use in Pregnancy on Birth Outcomes in Uganda
(AIDS and Behavior, 2023)Alcohol use and HIV infection are prevalent in sub-Saharan Africa (sSA), and both are associated with low birth weight. Yet, few studies have evaluated the combined effects of maternal HIV infection and alcohol use on birth ... -
Barriers and Facilitators to Utilization of Community Drug Distribution Points Among People Living with HIV in Bushenyi District, South-Western Uganda: A Qualitative Study
(HIV/AIDS-Research and Palliative Care, 2023)Introduction: People living with HIV (PLHIV) still have challenges in accessing HIV services in low- and middle-income countries (LMIC). In Uganda, community drug distribution points (CDDPs) are part of interventions to ... -
Use of symptom screening and sputum microscopy testing for active tuberculosis case detection among HIV-infected patients in real-world clinical practice in Uganda
(Journal of acquired immune deficiency syndromes, 2016)Background: The uptake of intensified active TB case finding among HIV-infected patients using symptom screening is not well understood. We evaluated the rate and completeness of each interim step in the TB “diagnostic ... -
Updating vital status by tracking in the community among patients with epidemic Kaposi sarcoma who are lost to follow-up in sub-Saharan Africa
(BMC cancer, 2017)Background: Throughout most of sub-Saharan Africa (and, indeed, most resource-limited areas), lack of death registries prohibits linkage of cancer diagnoses and precludes the most expeditious approach to determining cancer ... -
Factors associated with retention of health workers in remote public health centers in Northern Uganda: a cross‑sectional study
(Human Resources for Health, 2023)Background: Health worker retention in remote and hard-to-reach areas remains a threat in most low- and middle income countries, and this negatively impacts health service delivery. The health workforce inequity is ... -
Empiric Deworming and CD4 Count Recovery in HIVInfected Ugandans Initiating Antiretroviral Therapy
(PLoS neglected tropical diseases, 2014)Background: There is conflicting evidence on the immunologic benefit of treating helminth co-infections (‘‘deworming’’) in HIV-infected individuals. Several studies have documented reduced viral load and increased CD4 count ... -
Assessment of Bacterial Contamination and Antibiotic Susceptibility Patterns of Bacteria Isolated from Milk collected from Biharwe in Mbarara District: Cross-Sectional Study
(Journal of Veterinary Medicine and Surgery, 2022)Milk and dairy products are important source of vital nutrients for human beings. The unique composition and properties make milk an excellent medium for bacterial growth and source of bacterial infection. Milk borne ... -
The safety and utility of low-intensity pulsed ultrasound for effective blood–brain barrier penetration in the treatment of glioblastoma: a scoping review protocol
(Journal of Surgical Protocols and Research Methodologies, 2023)Glioblastoma(GBM) is one of the most aggressive central nervous system tumours with suboptimal treatment options and associated poor prognosis. A major impediment to Systemic treatment is the limitation of drug delivery ... -
Program Implementation of Option B– at a President’s Emergency Plan for AIDS Relief-Supported HIV Clinic Improves Clinical Indicators But Not Retention in Care in Mbarara, Uganda
(AIDS patient care and STDs, 2017)2013 WHO guidelines for prevention of mother to child transmission recommend combination antiretroviral therapy (ART) for all pregnant women, regardless of CD4 count (Option B/B+). We conducted a retrospective analysis of ... -
Validation of heart failure quality of life tool and usage to predict all-cause mortality in acute heart failure in Uganda: the Mbarara heart failure registry (MAHFER)
(BMC cardiovascular disorders, 2018)Background: The health-related quality of life (HRQoL) is an important treatment goal that could serve as low-cost prognostication tool in resource poor settings. We sought to validate the Kansas City Cardiomyopathy ... -
Factors Associated with 30-Day in-Hospital Mortality Among Patients Admitted with Severe Covid-19 in Mbarara Regional Referral Hospital
(Infection and drug resistance, 2022)Background: COVID-19 has created a burden on the healthcare system globally. Severe COVID-19 is linked with high hospital mortality. Data regarding 30-day in-hospital mortality and its factors has not been explored in ... -
Determination of the abortifacient activity of the aqueous extract of Phytolacca dodecandra (L’Her) leaf in Wistar rats
(African Journal of Pharmacy and Pharmacology, 2015)Throughout history women have tried to control their fertility using herbal remedies; traditionally Phytolacca dodecandra leaves have been used as an abortifacient. The objective of this study was to determine the ... -
Adherence to Antihypertensive Medication: An Interview Analysis of Southwest Ugandan Patients’ Perspectives
(Annals of Global Health., 2020)Background: Hypertension is a significant cardiovascular disease (CVD) and driver to CVD disorders in sub-Saharan Africa. It is a major independent risk factor for heart failure, stroke, and kidney failure. Per¬sons living ... -
Transitions from hospital to home: A mixed methods study to evaluate pediatric discharges in Uganda
(PLOS Global Public Health, 2023)The World Health Organization (WHO) Integrated Management of Childhood Illness (IMCI) guidelines recognize the importance of discharge planning to ensure continuation of care at home and appropriate follow-up. However, ... -
Going beyond the means: Exploring the role of bias from digital determinants of health in technologies
(PLOS Digital Health, 2023)Background: In light of recent retrospective studies revealing evidence of disparities in access to medical technology and of bias in measurements, this narrative review assesses digital determinants of health (DDoH) in ... -
Efficacy of midwife‑led role orientation of birth companions on maternal satisfaction and birth outcomes: a randomized control trial in Uganda
(BMC Pregnancy and Childbirth, 2023)Background: The World Health Organization recommends birth companionship for all women in labor. There is insufficient evidence on birth companionship in low-income settings and it is not clear if role orientation impacts ... -
Artemisia afra infusions clinical benefits as a complementary treatment to “WHO” approved drugs against tuberculosis
(Pharmacy & Pharmacology International Journal, 2022)In the past few years, the number of people infected with pulmonary tuberculosis has increased.1Today, it kills thousands in Africa alone, millions worldwide and the numbers keep on increasing due to COVID-19 (WHO, 2021). ... -
Molecular Detection of Cryptosporidium Species in Wildlife and Humans at the Wildlife-Human Interface around Queen Elizabeth National Park, Uganda
(Parasitologia, 2023)To date, information on Cryptosporidium spp. infection status among people and wild animals living at the wildlife-human interface such as Queen Elizabeth National Park (QENP) is scarce. The aim of this study is to document ... -
Effect of two counseling interventions on self-reported alcohol consumption, alcohol biomarker phosphatidylethanol (PEth), and viral suppression among persons living with HIV (PWH) with unhealthy alcohol use in Uganda: A randomized controlled trial
(Drug and alcohol dependence, 2023)Purpose: To test the efficacy of two interventions to reduce alcohol use and increase viral suppression compared to a control in persons with HIV (PWH). Methods: In a three-arm (1:1:1) randomized controlled trial (N = ... -
Retinopathy among women with hypertensive disorders of pregnancy attending hospitals in Mbarara city, south-western Uganda: a cross-sectional study
(BMJ open, 2023)Objective: Retinopathy is one of the complications occurring among women with hypertensive disorders of pregnancy. We sought to determine the prevalence and factors associated with retinopathy among women with hypertensive ...