Faculty of Medicine: Recent submissions
Now showing items 561-580 of 1979
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Immunogenicity and safety of fractional doses of 17D-213 yellow fever vaccine in children (YEFE): a randomised, double-blind, non-inferiority substudy of a phase 4 trial
(The Lancet Infectious Diseases, 2023)Background: Current supply shortages constrain yellow fever vaccination activities, particularly outbreak response. Although fractional doses of all WHO-prequalified yellow fever vaccines have been shown to be safe and ... -
Neural stem cell research in Africa: current realities and future prospects
(Biology Open, 2022)Neural stem cells (NSCs) are immature progenitor cells that are found in developing and adult brains that have the potential of dividing actively and renewing themselves, with a complex form of gene expression. The generation ... -
Beyond undetectable: Modeling the clinical benefit of improved antiretroviral adherence in persons with HIV with virologic suppression
(In Open Forum Infectious Diseases, 2023)Background: Incomplete antiretroviral therapy (ART) adherence has been linked to deleterious immunologic, inflammatory, and clinical consequences, even among virally suppressed (<50 copies/mL) persons with HIV (PWH). The ... -
Absconding among admitted patients with bipolar affective disorder diagnosis in Uganda
(BMC Psychiatry, 2023)Background: Hospitalization is often necessary for individuals with Bipolar affective Disorder (BAD) during severe manic or depressive episodes, as well as for stabilizing treatment regimens. However, a significant proportion ... -
A giant choledochal cyst in a 17 year old female managed in a resource limited setting: A case report
(International Journal of Surgery Case Reports, 2023)Introduction and importance: Choledochal cysts are rare congenital bile duct anomalies that lead to cystic dilatations of the biliary tree. This condition is very rare in Africa. When these cysts exceed 10 cm in diameter, ... -
Comparison of patient length of stay in care between homebased care and hospitalized covid-19 patients in northern and West Nile regions, Uganda
(Research square, 2023)SARS-CoV-2-caused COVID-19 was first detected in Wuhan, China, in December 2019. Uganda reported her first COVID-19 case on March 21, 2020. The pandemic placed an enormous burden on health systems across the world. This ... -
24 h mortality and its predictors among road traffic accident victims in a resource limited setting; a multicenter cohort study
(BMC surgery, 2023)Introduction: The incidence of road traffic accidents (RTAs) is on the rise contributing to the global burden of mortality as a major global health threat. It has been estimated that 93% of RTAs and more than 90% of the ... -
Risk factors for postpartum maternal mortality and hospital readmission in lowand middle‑income countries: a systematic review
(BMC Pregnancy and Childbirth, 2023)Background: In low- and middle-income countries, approximately two thirds of maternal deaths occur in the postpartum period. Yet, care for women beyond 24 h after discharge is limited. The objective of this systematic ... -
Unfavorable treatment outcomes among patients with drugresistant TB in Uganda
(The International Journal of Tuberculosis and Lung Disease, 2023)Background: Drug-resistant TB (DR-TB) remains a significant public health burden and a threat to the progress made in TB control and prevention in sub- Saharan Africa. Objective: To determine the risk-predictors of poor ... -
Permethrin-treated baby wraps for the prevention of malaria in children: Protocol for a double-blind, randomized placebocontrolled controlled trial in western Uganda
(Plos one, 2023)This article details the study protocol for a double-blind, randomized placebo-controlled trial to determine the effectiveness of permethrin-treated baby wraps to prevent Plasmodium falciparum malaria infection in children ... -
Perceived norms about male circumcision and personal circumcision status: a crosssectional, population-based study in rural Uganda
(medRxiv, 2023)Introduction: Over the past decade, 15 high-priority countries in eastern and southern Africa have promoted voluntary medical male circucmsion for HIV and STI prevention. Despite male circumcision prevalence in Uganda ... -
Diagnosis and management of ureterovaginal fistula in a resource limited setting: a 12 years’ experience at four fistula surgery centers in Uganda
(Research square, 2023)Background: Ureterovaginal fistulae usually follow iatrogenic injury to the ureter during pelvic surgery. This manifests as urine incontinence and results in serious psychosocial effects to the women. Ureterovaginal fistulae ... -
Coinfection of COVID-19 and Tuberculosis in Uganda
(The American Journal of Tropical Medicine and Hygiene, 2023)The clinical features and outcomes of tuberculosis (TB) and COVID-19 coinfection are not well established. This short report describes 11 people with TB/COVID-19 coinfection in Uganda. The mean age was 46.9 6 14.5 years; ... -
Prevalence of Nasal Carriage of Methicillin Resistant Staphylococcus aureus among Patients, Health Care Workers and Patients’ Care Takers at Kabale Regional Referral Hospital, South Western Uganda
(Research square, 2023)Background: Methicillin Resistant Staphylococcus aureus (MRSA) is a type of Gram-positive bacterium that is genetically different from other strains of Staphylococcus aureus by virtue its capability to overcome the actions ... -
Leveraging tele-mentoring and remote learning to strengthen the emergency care capacity of health workers in Uganda
(African Journal of Emergency Medicine, 2023)Background: A robust emergency care system is a cost-effective method of reducing preventable death and dis- ability, especially in low-and middle-income countries. To scale emergency care expertise across the country, the ... -
Umbilical Stump Colonization and Antibiotic Susceptibility Patterns of Bacteria from Umbilical Stumps of Neonates Admitted at Holy Innocents Children’s Hospital, Mbarara, South Western Uganda
(Research square, 2023)Introduction: Every year a million deaths of neonates occur worldwide due to bacteria that has ascended through the umbilical stump leading to serious infection. An umbilical stump that has just separated is known to be ... -
“If you have light, your heart will be at peace”: A qualitative study of household lighting and social integration in southwestern Uganda
(Journal of Global Health, 2023)Background: Expanding electrification and access to other clean and affordable energy, such as solar energy, is a critical component of the Sustainable Development Goals, particularly in sub-Saharan Africa where 70% of ... -
High prevalence of risky sexual behaviour among key populations receiving antiretroviral therapy at a large HIV clinic in northern Uganda
(African Health Sciences, 2023)Background: Risky sexual behaviour (RSB) among key populations pose a significant risk of human immunodeficiency virus (HIV) infection but remains understudied. Objectives: We assessed the prevalence and factors associated ... -
Private sector antimalarial sales a decade after “test and treat”: A cross-sectional study of drug shop clients in rural Uganda
(Frontiers in Public Health, 2023)Background: The World Health Organization has promoted “test and treat” guidelines for malaria since 2010, recommending all suspected malaria cases be confirmed with a parasitological test, typically a rapid diagnostic ... -
Prevalence and factors associated with drug therapy problems among hypertensive patients at hypertension clinic of Mbarara Regional Referral Hospital, Uganda: a |cross-sectional study
(Therapeutic Advances in Cardiovascular Disease, 2023)Background: Despite the use of safe and effective conventional drugs, drug therapy problems (DTPs) pose a threat to the successful management of hypertension. DTPs are of a great concern in health care because of their ...